Evidence that Hsc70 negatively modulates the activation of the heme‐regulated eIF‐2α kinase in rabbit reticulocyte lysate

Interaction of Hsp 70 with Newly Synthesized Proteins: Implications for Protein Folding and Assembly

1990 • 1,293 citations

TRANSLATIONAL CONTROL IN MAMMALIAN CELLS

1991 • 1,041 citations

Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones

1994 • 651 citations

Hsp70 Prevents Activation of Stress Kinases

1997 • 516 citations

An enzyme that removes clathrin coats: purification of an uncoating ATPase.

1984 • 449 citations

A hitchhiker's guide to the human Hsp70 family

1996 • 378 citations

ATP-induced protein Hsp70 complex dissociation requires K+ but not ATP hydrolysis

1993 • 366 citations

Regulation of protein synthesis by heme-regulated eIF-2α kinase

1995 • 297 citations

Heat shock-induced translational alterations in HeLa cells. Initiation factor modifications and the inhibition of translation.

1984 • 282 citations

Control of globin synthesis: The role of heme

1972 • 257 citations

Protein synthesis and protein phosphorylation during heat stress, recovery, and adaptation.

1989 • 203 citations

Techniques in protein modification

1995 • 173 citations

ATP-dependent chaperoning activity of reticulocyte lysate

1994 • 143 citations

Activation of the Double-stranded RNA-regulated Protein Kinase by Depletion of Endoplasmic Reticular Calcium Stores

1995 • 126 citations

Modulators of the eukaryotic heat shock response

1986 • 114 citations

Evidence that glucose 6-phosphate regulates protein synthesis initiation in reticulocyte lysates.

1978 • 104 citations

Complexes between nascent polypeptides and their molecular chaperones in the cytosol of mammalian cells.

1997 • 101 citations

Mechanism of translational control by partial phosphorylation of the alpha subunit of eukaryotic initiation factor 2.

1984 • 94 citations

Specific interaction between a subset of the p53 protein family and heat shock proteins hsp72/hsc73 in a human osteosarcoma cell line.

1988 • 92 citations

Hsp90 Is Obligatory for the Heme-regulated eIF-2α Kinase to Acquire and Maintain an Activable Conformation

1997 • 85 citations

The regulation of initiation of protein synthesis by phosphorylation of eIF-2(alpha) and the role of reversing factor in the recycling of eIF-2.

1984 • 79 citations

ATP catalyzes the sequestration of clathrin during enzymatic uncoating.

1985 • 73 citations

Interactions of liver Grp78 and Escherichia coli recombinant Grp78 with ATP: multiple species and disaggregation.

1992 • 73 citations

Independent Signaling of grp78 Gene Transcription and Phosphorylation of Eukaryotic Initiation Factor 2α by the Stressed Endoplasmic Reticulum

1995 • 72 citations

Expression of a phosphorylation-resistant eukaryotic initiation factor 2 alpha-subunit mitigates heat shock inhibition of protein synthesis

1993 • 71 citations

Interactions of the heme-regulated eIF-2 alpha kinase with heat shock proteins in rabbit reticulocyte lysates.

1992 • 71 citations

Protection of Chinese Hamster Ovary Cells from Hyperthermic Killing by Cycloheximide or Puromycin

1986 • 69 citations

In situ phosphorylation of the α subunit of eukaryotic initiation factor 2 in reticulocyte lysates inhibited by heme deficiency, double-stranded RNA, oxidized glutathione, or the heme-regulated protein kinase

1979 • 68 citations

The Roles of Sugar Phosphates and Thiol-Reducing Systems in the Control of Reticulocyte Protein Synthesis

1983 • 64 citations

12 Regulation of Protein Synthesis

1987 • 60 citations

The Use of Affinity Chromatography on 2'5' ADP-Sepharose Reveals a Requirement for NADPH, Thioredoxin and Thioredoxin Reductase for the Maintenance of High Protein Synthesis Activity in Rabbit Reticulocyte Lysates

1983 • 58 citations

Inhibition of rabbit reticulocyte lysate protein synthesis by heavy metal ions involves the phosphorylation of the alpha-subunit of the eukaryotic initiation factor 2.

1987 • 54 citations

Evaluation of protein phosphorylation state by a combination of vertical slab gel isoelectric focusing and immunoblotting

1989 • 54 citations

Toxic heavy metal ions activate the heme-regulated eukaryotic initiation factor-2 alpha kinase by inhibiting the capacity of hemin-supplemented reticulocyte lysates to reduce disulfide bonds

1991 • 54 citations

Denatured proteins inhibit translation in hemin-supplemented rabbit reticulocyte lysate by inducing the activation of the heme-regulated eIF-2.alpha. kinase

1993 • 53 citations

Translational repression by chemical inducers of the stress response occurs by different pathways

1987 • 50 citations

Effect of Constitutive 70-kDa Heat Shock Protein Polymerization on Its Interaction with Protein Substrate

1996 • 50 citations

Control of protein synthesis by hemin. Isolation and characterization of a supernatant factor from rabbit reticulocyte lysate

1976 • 50 citations

Polymerization of 70-kDa Heat Shock Protein by Yeast DnaJ in ATP

1995 • 50 citations

Translational Control In Mammalian Cells

1991 • 47 citations

The relationship between protein synthesis and heat shock proteins levels in rabbit reticulocyte lysates.

1992 • 41 citations

Effects of hemin and porphyrin compounds on intersubunit disulfide formation of heme-regulated eIF-2 alpha kinase and the regulation of protein synthesis in reticulocyte lysates.

1992 • 38 citations

Recycling and phosphorylation of eukaryotic initiation factor 2 on 60S subunits of 80S initiation complexes and polysomes.

1992 • 27 citations

Dissociation of glucose-regulated protein Grp78 and Grp78-IgE Fc complexes by ATP.

1993 • 24 citations

Reduced Formation of Initiation Complexes between Met-tRNAf and 40-S Ribosomal Subunits in Rabbit Reticulocyte Lysates Incubated at Elevated Temperatures. Activity of the Met-tRNAf Binding Factor

1978 • 22 citations

THE CONTROL OF PROTEIN SYNTHESIS IN RABBIT RETICULOCYTE LYSATES

1979 • 11 citations

Effect of oxidizing agents and haemin on the phosphorylation of eukaryotic elongation factor 2 in rabbit reticulocyte lysates

1995 • 4 citations