Translational repression by chemical inducers of the stress response occurs by different pathways

Heat shock, from bacteria to man

1982 • 1,260 citations

The effect of amino acid analogues and heat shock on gene expression in chicken embryo fibroblasts

1978 • 547 citations

The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels

1982 • 542 citations

RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis

1986 • 524 citations

Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control. Heat shock effects on eIF-4F.

1987 • 494 citations

Transition series metals and sulfhydryl reagents induce the synthesis of four proteins in eukaryotic cells

1980 • 343 citations

Heat shock-induced translational alterations in HeLa cells. Initiation factor modifications and the inhibition of translation.

1984 • 282 citations

Trauma-Induced Protein in Rat Tissues: A Physiological Role for a "Heat Shock" Protein?

1981 • 233 citations

Phorbol ester, calcium ionophore, or serum added to quiescent rat embryo fibroblast cells all result in the elevated phosphorylation of two 28,000-dalton mammalian stress proteins.

1985 • 233 citations

Identification and quantitation of levels of protein synthesis initiation factors in crude HeLa cell lysates by two-dimensional polyacrylamide gel electrophoresis.

1983 • 193 citations

Modulation of heat shock polypeptide synthesis in HeLa cells during hyperthermia and recovery

1982 • 162 citations

Regulation of initiation factors during translational repression caused by serum depletion. Covalent modification.

1985 • 153 citations

Synthesis of heat-shock proteins in developing sea urchins

1981 • 125 citations

Guanine nucleotides, protein phosphorylation and the control of translation

1986 • 124 citations

Evaluation of isoelectric focusing running conditions during two-dimensional isoelectric focusing/sodium dodecyl sulfate-polyacrylamide gel electrophoresis: Variation of gel patterns with changing conditions and optimized isoelectric focusing conditions

1984 • 114 citations

Mechanism of inhibition of polypeptide chain initiation in heat-shocked Ehrlich cells involves reduction of eukaryotic initiation factor 4F activity.

1985 • 101 citations

Translation in vitro of Drosophila heat-shock messages

1977 • 88 citations

Activation of hemin-regulated initiation factor-2 kinase in heat-shocked HeLa cells.

1986 • 84 citations

Heat-shock proteins are associated with hnRNA in Drosophila melanogaster tissue culture cells

1983 • 83 citations

The regulation of initiation of protein synthesis by phosphorylation of eIF-2(alpha) and the role of reversing factor in the recycling of eIF-2.

1984 • 79 citations

Immunofluorescence localization of a small heat shock protein (hsp 23) in salivary gland cells of Drosophila melanogaster

1981 • 69 citations

Heat shock alters nuclear ribonucleoprotein assembly in Drosophila cells.

1983 • 65 citations

Regulation of initiation factors during translational repression caused by serum depletion. Abundance, synthesis, and turnover rates.

1985 • 63 citations

Preferential stimulation of rabbit α globin mRNA translation by a cap-binding protein complex

1984 • 57 citations

Changes in eukaryotic gene expression in response to environmental stress

1986 • 56 citations

Mechanism of inhibition of polypeptide chain initiation in heat‐shocked Ehrlich ascites tumour cells

1984 • 50 citations

Initiation factor protein modifications and inhibition of protein synthesis.

1987 • 46 citations

Metal binding drugs induce synthesis of four proteins in normal cells

1979 • 29 citations

Inhibition of HeLa cell protein synthesis under heat shock conditions in the absence of initiation factor eIF-2α phosphorylation

1986 • 19 citations

Translation in micrococcal nuclease-treated cell-free extracts from Ehrlich ascites tumor cells

1984 • 8 citations