An atypical topoisomerase II from archaea with implications for meiotic recombination

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1990 • 5,831 citations

Life with 6000 Genes

1996 • 4,125 citations

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Complete Genome Sequence of the Methanogenic Archaeon, Methanococcus jannaschii

1996 • 2,043 citations

Mutation of a mutL Homolog in Hereditary Colon Cancer

1994 • 1,834 citations

DNA TOPOISOMERASES

1996 • 1,771 citations

Meiosis-Specific DNA Double-Strand Breaks Are Catalyzed by Spo11, a Member of a Widely Conserved Protein Family

1997 • 1,751 citations

2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

1994 • 1,472 citations

A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae

1990 • 683 citations

Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination

1990 • 591 citations

Crystal structure of an N-terminal fragment of the DNA gyrase B protein

1991 • 526 citations

Extensive 3′-overhanging, single-stranded DNA associated with the meiosis-specific double-strand breaks at the ARG4 recombination initiation site

1991 • 525 citations

Phylogenetic analysis of the 90 kD heat shock family of protein sequences and an examination of the relationship among animals, plants, and fungi species.

1995 • 301 citations

Covalent protein-DNA complexes at the 5' strand termini of meiosis-specific double-strand breaks in yeast.

1995 • 200 citations

Homologous pairing is reduced but not abolished in asynaptic mutants of yeast.

1994 • 178 citations

The location and structure of double-strand DNA breaks induced during yeast meiosis: evidence for a covalently linked DNA-protein intermediate.

1995 • 169 citations

Advances in pharmacology

1966 • 160 citations

The nucleotide mapping of DNA double-strand breaks at the CYS3 initiation site of meiotic recombination in Saccharomyces cerevisiae.

1995 • 129 citations

Construction and use of halobacterial shuttle vectors and further studies on Haloferax DNA gyrase

1991 • 119 citations

Two eukaryote-specific regions of Hsp82 are dispensable for its viability and signal transduction functions in yeast

1996 • 114 citations

Purification of a DNA topoisomerase II from the hyperthermophilic archaeon Sulfolobus shibatae. A thermostable enzyme with both bacterial and eucaryal features.

1994 • 103 citations

Transient, meiosis-induced expression of the rec6 and rec12 genes of Schizosaccharomyces pombe.

1994 • 103 citations

Isolation, DNA sequence, and regulation of a meiosis-specific eukaryotic recombination gene.

1987 • 103 citations

Appendix II: Alignment of Primary Sequences of DNA Topoisomerases

1994 • 97 citations

Identifying the catalytic residue of the ATPase reaction of DNA gyrase.

1993 • 94 citations

Dominant negative mutator mutations in the mutL gene of Escherichia coli

1996 • 83 citations

Initiation of recombination in Saccharomyces cerevisiae haploid meiosis.

1994 • 80 citations

A Bipartite Operator Interacts with a Heat Shock Element To Mediate Early Meiotic Induction of Saccharomyces cerevisiae HSP82

1995 • 38 citations

Meiotic recombination in yeast

1993 • 25 citations