Gene expression of the transcription factor NF-κ B in hippocampus: regulation by synaptic activity

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

The regulation of transcription by phosphorylation

1992 • 1,316 citations

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

1990 • 1,202 citations

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

1988 • 1,200 citations

NF-κB Controls Expression of Inhibitor IκBα: Evidence for an Inducible Autoregulatory Pathway

1993 • 1,141 citations

The inducible transcription activator NF-κB: regulation by distinct protein subunits

1991 • 1,079 citations

Neurobiology of learning and memory

1985 • 1,024 citations

Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation

1989 • 1,014 citations

IMF-κB and Rel: Participants in a Multiform Transcriptional Regulatory System

1993 • 967 citations

Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal

1990 • 870 citations

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

1991 • 746 citations

Differential expression of immediate early genes in the hippocampus and spinal cord

1990 • 670 citations

DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide

1991 • 604 citations

Translocation of Protein Kinase C Activity May Mediate Hippocampal Long-Term Potentiation

1986 • 532 citations

Selection of Optimal κB/Rel DNA-Binding Motifs: Interaction of Both Subunits of NF-κB with DNA Is Required for Transcriptional Activation

1992 • 501 citations

Constitutive NF-kB Activity in Neurons

1994 • 400 citations

In Vitro Activation and Nuclear Translocation of NF-κB Catalyzed by Cyclic AMP-Dependent Protein Kinase and Protein Kinase C

1989 • 389 citations

The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms.

1993 • 361 citations

Electrotonic Processing of Information by Brain Cells

1976 • 348 citations

Thresholds for synaptic activation of transcription factors in hippocampus: correlation with long-term enhancement

1993 • 345 citations

Constitutive NF-kappa B activity in neurons.

1994 • 304 citations

Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation.

1992 • 286 citations

The role of protein kinase C in long-term potentiation: a testable model

1989 • 278 citations

IκBγ, a 70 kd protein identical to the C-terminal half of p110 NF-κB: A new member of the IκB family

1992 • 274 citations

The characterization of the promoter of the gene encoding the p50 subunit of NF-kappa B indicates that it participates in its own regulation.

1992 • 258 citations

Distinct combinations of NF-kappa B subunits determine the specificity of transcriptional activation.

1992 • 245 citations

Cloning of the DNA-binding subunit of human nuclear factor kappa B: the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor alpha.

1991 • 230 citations

Brain synapses contain inducible forms of the transcription factor NF-κB

1993 • 225 citations

Hippocampal protein kinase C activity is reduced in poor spatial learners

1990 • 225 citations

In vitro activation and nuclear translocation of NF-kappa B catalyzed by cyclic AMP-dependent protein kinase and protein kinase C.

1989 • 220 citations

Variable Effects of Phosphorylation of Pit-1 Dictated by the DNA Response Elements

1991 • 206 citations

Direct relation of long-term synaptic potentiation to phosphorylation of membrane protein F1, a substrate for membrane protein kinase C

1986 • 201 citations

Autoregulation of the NF-kappa B transactivator RelA(p65) by multiple cytoplasmic inhibitors containing ankyrinmotifs.

1994 • 187 citations

Protein kinase C phosphorylates a 47 Mr protein (F1) directly related to synaptic plasticity

1985 • 186 citations

Long-term potentiation and the induction of c-fos mRNA and proteins in the dentate gyrus of unanesthetized rats

1989 • 185 citations

Classical conditioning induces long-term translocation of protein kinase C in rabbit hippocampal CA1 cells.

1988 • 167 citations

The 65-kD subunit of NF-kappa B is a receptor for I kappa B and a modulator of DNA-binding specificity.

1990 • 167 citations

Phosphorylation of the presynaptic protein B-50 (GAP-43) is increased during electrically induced long-term potentiation

1992 • 160 citations

A brain-specific transcription activator

1989 • 141 citations

Long-term potentiation as synaptic dialogue

1993 • 122 citations

Inhibition of protein kinase C blocks two components of LTP persistence, leaving initial potentiation intact

1990 • 107 citations

Selective expression of protein F1/(GAP-43) mRNA in pyramidal but not granule cells of the hippocampus

1991 • 104 citations

Promoter of the human NF-kappa B p50/p105 gene. Regulation by NF-kappa B subunits and by c-REL.

1993 • 104 citations

NF-κB-like factors in the murine brain. Developmentally-regulated and tissue-specific expression

1993 • 99 citations

Memory formation in the chick depends on membrane-bound protein kinase C

1990 • 97 citations

Learning selectively increases protein kinase C substrate phosphorylation in specific regions of the chick brain.

1993 • 93 citations

Expression Directed from HIV Long Terminal Repeats in the Central Nervous System of Transgenic Mice

1992 • 89 citations

The two major phosphoproteins in growth cones are probably identical to two protein kinase C substrates correlated with persistence of long- term potentiation

1989 • 88 citations

Enkephalin biosynthesis and enkephalin gene expression are increased in hippocampal mossy fibers following a unilateral lesion of the hilus

1987 • 86 citations

NF-kappa B activates the HIV promoter in neurons.

1993 • 85 citations

Systemic administration of kainic acid differentially regulates the levels of prodynorphin and proenkephalin mRNA and peptides in the rat hippocampus

1991 • 78 citations

Post-training intrahippocampal infusion of protein kinase C inhibitors causes amnesia in rats

1994 • 71 citations

Nuclear factor kappa B activates proenkephalin transcription in T lymphocytes.

1991 • 65 citations

Protein kinase C inhibitors prevent induction and continued expression of cell memory in Hermissenda type B photoreceptors.

1991 • 63 citations

Transsynaptic Expression of a Presynaptic Glutamate Receptor During Hippocampal Long-Term Potentiation

1993 • 62 citations

N-myc disrupts protein kinase C-mediated signal transduction in neuroblastoma.

1991 • 56 citations

Protein kinase C and F1/GAP-43 gene expression in hippocampus inversely related to synaptic enhancement lasting 3 days.

1993 • 48 citations

Nuclear factor-κB in rat brain: Enhanced DNA-binding activity following convulsant-induced seizures

1994 • 45 citations

Prodynorphin gene expression relates to NF-κB factors

1994 • 31 citations

Brief exposure to a novel environment enhances binding of hippocampal transcription factors to their DNA recognition elements

1993 • 19 citations