Scorpion Toxins Affecting Sodium Current Inactivation Bind to Distinct Homologous Receptor Sites on Rat Brain and Insect Sodium Channels

Inactivation of the sodium channel. I. Sodium current experiments.

1977 • 1,509 citations

Neurotoxins that Act on Voltage-Sensitive Sodium Channels in Excitable Membranes

1980 • 1,236 citations

MOLECULAR PROPERTIES OF VOLTAGE-SENSITIVE SODIUM CHANNELS

1986 • 577 citations

Molecular analysis of the para locus, a sodium channel gene in Drosophila

1989 • 501 citations

Handbook of Neurotoxicology

1995 • 405 citations

A rapid method for preparing synaptosomes: Comparison, with alternative procedures

1981 • 392 citations

Purification of Animal Neurotoxins

1970 • 348 citations

Advances in Cytopharmacology

1973 • 345 citations

Functional Modulation of Brain Sodium Channels by Protein Kinase C Phosphorylation

1991 • 325 citations

Two types of scorpion toxin receptor sites, one related to the activation, the other to the inactivation of the action potential sodium channel

1982 • 266 citations

Two types of scorpion neurotoxins characterized by their binding to two separate receptor sites on rat brain synaptosomes

1980 • 242 citations

An Integrated view of the Molecular Toxinology of Sodium Channel Gating in Excitable Cells

1987 • 221 citations

Sea anemone toxin and scorpion toxin share a common receptor site associated with the action potential sodium ionophore.

1978 • 187 citations

A scorpion venom neurotoxin paralytic to insects that affects sodium current inactivation: purification, primary structure, and mode of action

1990 • 165 citations

An excitatory and a depressant insect toxin from scorpion venom both affect sodium conductance and possess a common binding site

1985 • 147 citations

Purification and properties of the insect toxin from the venom of the scorpion Androctonus australis Hector

1971 • 143 citations

Wie sind Reihenversuche für biologische Auswertungen am zweckmäßigsten anzuordnen?

1934 • 141 citations

Functional duality and structural uniqueness of the depressant insect-selective neurotoxins

1991 • 133 citations

A new neurotoxin receptor site on sodium channels is identified by a conotoxin that affects sodium channel inactivation in molluscs and acts as an antagonist in rat brain.

1994 • 122 citations

Covalent structure of the insect toxin of the North African scorpion Androctonus australis Hector

1982 • 120 citations

Biochemical properties of sodium channels in a wide range of excitable tissues studied with site-directed antibodies

1988 • 114 citations

Binding of scorpion toxin to receptor sites associated with voltage-sensitive sodium channels in synaptic nerve ending particles.

1978 • 113 citations

Mechanism of action of a polypeptide neurotoxin from the coral Goniopora on sodium channels in mouse neuroblastoma cells.

1986 • 104 citations

Radioiodination of scorpion and snake toxins

1977 • 102 citations

Tityus serrulatus toxin VII bears pharmacological properties of both β-toxin and insect toxin from scorpion venoms

1986 • 100 citations

Localization of receptor sites for insect-selective toxins on sodium channels by site-directed antibodies

1992 • 98 citations

Actions of insect toxin and other toxins derived from the venom of the scorpion Androctonus australis on isolated giant axons of the cockroach (Periplaneta americana)

1982 • 97 citations

Neurotoxins: overview of an emerging research technology

1994 • 94 citations

Binding of scorpion toxins to rat brain synaptosomal fraction. Effects of membrane potential, ions, and other neurotoxins

1980 • 92 citations

Scorpion venoms and neurotoxins: An immunological study

1981 • 88 citations

The binding of the insect selective neurotoxin (AaIT) from scorpion venom to locust synaptosomal membranes

1984 • 87 citations

Binding of scorpion and sea anemone neurotoxins to a common site related to the action potential Na+ ionophore in neuroblastoma cells

1978 • 85 citations

Structure-function relationships of sea anemone toxin II from Anemonia sulcata.

1981 • 84 citations

Pharmacological properties of insect axons: A review

1982 • 82 citations

Disulfide Bonds of Toxin II of the Scorpion Androctonus australis Hector

1974 • 81 citations

Purification and physiological characterization of neurotoxins from venoms of the scorpions centruroides sculpturatus and leiurus quinquestriatus.

1983 • 78 citations

Structure and Function in Excitable Cells

1983 • 76 citations

α-Scorpion Toxins Binding on Rat Brain and Insect Sodium Channels Reveal Divergent Allosteric Modulations by Brevetoxin and Veratridine

1995 • 72 citations

A factor toxic to crustacean in the venom of the scorpion Androctonus australis hector

1972 • 66 citations

Binding of an α scorpion toxin to insect sodium channels is not dependent on membrane potential

1993 • 65 citations

Characterization of toxin III of the scorpion Leiurus quinquestriatus quinquestriatus: A new type of alpha‐toxin highly toxic both to mammals and insects

1993 • 62 citations

Sodium channel internalization in developing neurons

1994 • 61 citations

Current-Voltage Relations in the Isolated Giant Axon of the Cockroach Under Voltage-Clamp Conditions*

1967 • 59 citations

A New Conotoxin Affecting Sodium Current Inactivation Interacts with the δ-Conotoxin Receptor Site

1995 • 58 citations

Alteration of Sodium Currents by New Peptide Toxins From the Venom of a Molluscivorous Conus Snail

1993 • 53 citations

Allosteric modulation of neurotoxin binding to voltage-sensitive sodium channels by Ptychodiscus brevis toxin 2.

1987 • 50 citations

On the binding of two scorpion toxins to the central nervous system of the cockroach Periplaneta americana

1989 • 49 citations

Scorpion toxin: Specific binding to rat synaptosomes

1978 • 49 citations

The voltage-dependent Na+ channel of insect nervous system identified by receptor sites for tetrodotoxin, and scorpion and sea anemone toxins

1985 • 47 citations

The interaction of sea anemone and scorpion neurotoxins with tetrodotoxin-resistant Na+ channels in rat myoblasts. A comparison with Na+ channels in other excitable and non-excitable cells.

1984 • 46 citations

Pharmacological properties of sodium channels in cultured rat heart cells.

1981 • 45 citations

Primary structure of toxin IV of Leiurus quinquestriatus quinquestriatus

1985 • 44 citations

Variability among insect sodium channels revealed by selective neurotoxins

1994 • 40 citations

Sodium channel polypeptides in central nervous systems of various insects identified with site directed antibodies

1990 • 39 citations

The interaction of polypeptide neurotoxins with tetrodotoxin-resistant Na+ channels in mammalian cardiac cells. Correlation with inotropic and arrhythmic effects

1986 • 38 citations

The binding of an insect-selective neurotoxin and saxitoxin to insect neuronal membranes

1985 • 38 citations

Classification of scorpion toxins according to amino acid composition and sequence

1984 • 36 citations

Covalent structure of toxins I and II from the scorpion Buthus occitanus tunetanus

1983 • 33 citations

Characterization of six toxins from the venom of the Moroccan scorpion Buthus occitanus mardochei

1987 • 32 citations

Actions of a polypeptide toxin from the marine snail Conus striatus on voltage-sensitive sodium channels.

1987 • 30 citations

Actions of three structurally distinct sea anemone toxins on crustacean and insect sodium channels

1992 • 29 citations

Insect Specific Neurotoxins from Scorpion Venom that Affect Sodium Current Inactivation

1994 • 21 citations

Changes in Na channel properties of frog and rat skeletal muscles induced by the AaH II toxin from the scorpion Androctonus australis

1989 • 21 citations

Ion channels in nerve and muscle cells

1990 • 20 citations

Pharmacology of survival: insect selective neurotoxins derived from scorpion venom

1987 • 19 citations

Solubilization and characterization of the insect neuronal sodium channel

1991 • 12 citations

[3H]Batrachotoxinin A-20-α-benzoate Binding in Synaptosomes from Susceptible and kdr-Type Resistant German Cockroaches, Blattella germanica (L.)

1993 • 8 citations

Biochemical characterization of insect neuronal sodium channels

1993 • 5 citations