Increased expression of thrombomodulin on the cultured human umbilical vein endothelial cells and mouse hemangioma cells by cyclic AMP

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

The Roles of Protein C and Thrombomodulin in the Regulation of Blood Coagulation

1989 • 1,059 citations

Stimulation of Endothelial Cell Prostacyclin Production by Thrombin, Trypsin, and the Ionophore A 23187

1978 • 715 citations

The Regulation of Natural Anticoagulant Pathways

1987 • 702 citations

Synthesis of fibrinolytic activator and inhibitor by endothelial cells

1977 • 484 citations

Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro.

1987 • 467 citations

The pathophysiology of the prethrombotic state in humans: insights gained from studies using markers of hemostatic system activation

1987 • 395 citations

Tumor Necrosis Factor Suppresses Transcription of the Thrombomodulin Gene in Endothelial Cells

1988 • 367 citations

Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation.

1987 • 358 citations

Tumor necrosis factor leads to the internalization and degradation of thrombomodulin from the surface of bovine aortic endothelial cells in culture

1989 • 337 citations

Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells.

1988 • 284 citations

The turnover of thrombin-thrombomodulin complex in cultured human umbilical vein endothelial cells and A549 lung cancer cells. Endocytosis and degradation of thrombin.

1985 • 149 citations

Characterization of a virus that causes transient aplastic crisis.

1984 • 146 citations

Identification of fetomodulin, a surface marker protein of fetal development, as thrombomodulin by gene cloning and functional assays

1990 • 86 citations

Coagulation factor Va binds to human umbilical vein endothelial cells and accelerates protein C activation.

1984 • 85 citations

The structure and function of mouse thrombomodulin. Phorbol myristate acetate stimulates degradation and synthesis of thrombomodulin without affecting mRNA levels in hemangioma cells.

1988 • 84 citations

Fetomodulin: Marker surface protein of fetal development which is modulatable by cyclic AMP

1987 • 64 citations

Localization and Biosynthesis of Functional Thrombomodulin in Human Megakaryocytes and a Human Megakaryoblastic Cell Line (MEG-01)

1990 • 29 citations

Enhanced expression of thrombomodulin by intracellular cyclic AMP-increasing agents in two human megakaryoblastic leukemia cell lines

1990 • 28 citations