Localization and Biosynthesis of Functional Thrombomodulin in Human Megakaryocytes and a Human Megakaryoblastic Cell Line (MEG-01)

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Modulation of endothelial cell hemostatic properties by tumor necrosis factor.

1986 • 1,335 citations

Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.

1981 • 831 citations

The Regulation of Natural Anticoagulant Pathways

1987 • 702 citations

Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity.

1986 • 592 citations

Human Plasma Protein C

1979 • 511 citations

The inhibition of blood coagulation by activated protein C through the selective inactivation of activated factor V

1979 • 480 citations

Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro.

1987 • 467 citations

The Regulation of Hemostasis: The Protein C System

1986 • 443 citations

Thrombomodulin is found on endothelium of arteries, veins, capillaries, and lymphatics, and on syncytiotrophoblast of human placenta.

1985 • 413 citations

Inactivation of human coagulation factor V by activated protein C.

1983 • 374 citations

Establishment of a novel human megakaryoblastic leukemia cell line, MEG- 01, with positive Philadelphia chromosome

1985 • 323 citations

Proteolytic inactivation of human factor VIII procoagulant protein by activated human protein C and its analogy with factor V

1984 • 287 citations

The turnover of thrombin-thrombomodulin complex in cultured human umbilical vein endothelial cells and A549 lung cancer cells. Endocytosis and degradation of thrombin.

1985 • 149 citations

Identification and quantitation of protein S in human platelets

1985 • 119 citations

Functional and morphological differentiation induction of a human megakaryoblastic leukemia cell line (MEG-01s) by phorbol diesters

1988 • 113 citations

Functionally Active Thrombomodulin Is Present in Human Platelets1

1988 • 107 citations

Incorporation of a circulating protein into megakaryocyte and platelet granules.

1987 • 99 citations

Binding of Thrombin to Human Platelets and its Possible Significance

1976 • 71 citations

Evidence for a single class of thrombin-binding sites on human platelets

1976 • 70 citations

Identification of the thrombin receptor on human platelets by chemical crosslinking.

1986 • 69 citations

Biosynthesis and secretion of functional protein S by a human megakaryoblastic cell line (MEG-01)

1987 • 67 citations

Inhibition of thrombin-induced platelet aggregation by a derivative of wheat germ agglutinin. Evidence for a physiologic receptor of thrombin in human platelets

1981 • 24 citations

A novel thrombin-reactive protein complex in human platelets.

1983 • 17 citations

The relationship between thrombomodulin expression and cell cycle stages in cultured rabbit endothelial cells

1984 • 4 citations