Parallel Quorum Sensing Systems Converge to Regulate Virulence in Vibrio cholerae

Quorum Sensing in Bacteria

2001 • 4,724 citations

The Involvement of Cell-to-Cell Signals in the Development of a Bacterial Biofilm

1998 • 3,303 citations

Molecular biological access to the chemistry of unknown soil microbes: a new frontier for natural products

1998 • 1,855 citations

DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae

2000 • 1,833 citations

Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones

1997 • 1,678 citations

Structural identification of a bacterial quorum-sensing signal containing boron

2002 • 1,491 citations

Cloning the Soil Metagenome: a Strategy for Accessing the Genetic and Functional Diversity of Uncultured Microorganisms

2000 • 1,239 citations

Cellular Control of the Synthesis and Activity of the Bacterial Luminescent System

1970 • 1,230 citations

Bacterial Quorum Sensing in Pathogenic Relationships

2000 • 1,102 citations

Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa

1999 • 1,056 citations

Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin.

1987 • 1,041 citations

The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum‐sensing signal molecule

2001 • 991 citations

Structural identification of autoinducer of Photobacterium fischeri luciferase

1981 • 972 citations

A Plant Flavone, Luteolin, Induces Expression of Rhizobium meliloti Nodulation Genes

1986 • 967 citations

Quorum sensing in Escherichia coli , Salmonella typhimurium , and Vibrio harveyi : A new family of genes responsible for autoinducer production

1999 • 945 citations

Epidemiology, Genetics, and Ecology of Toxigenic Vibrio cholerae

1998 • 904 citations

[31] Analysis and construction of stable phenotypes in gram-negative bacteria with Tn5- and Tn10-derived minitransposons

1994 • 887 citations

Quorum-sensing regulators control virulence gene expression in Vibrio cholerae

2002 • 826 citations

AiiA, an enzyme that inactivates the acylhomoserine lactone quorum-sensing signal and attenuates the virulence of Erwinia carotovora

2000 • 786 citations

Quorum sensing by peptide pheromones and two‐component signal‐transduction systems in Gram‐positive bacteria

1997 • 773 citations

Detecting and characterizing N -acyl-homoserine lactone signal molecules by thin-layer chromatography

1997 • 744 citations

Intercellular signalling in Vibrio harveyi: sequence and function of genes regulating expression of luminescence

1993 • 741 citations

Cross-species induction of luminescence in the quorum-sensing bacterium Vibrio harveyi

1997 • 737 citations

Multiple signalling systems controlling expression of luminescence in Vibrio harveyi: sequence and function of genes encoding a second sensory pathway

1994 • 681 citations

Identification of genes and gene products necessary for bacterial bioluminescence.

1984 • 615 citations

Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover

2002 • 582 citations

Acyl homoserine-lactone quorum-sensing signal generation

1999 • 570 citations

Cannibalism by Sporulating Bacteria

2003 • 557 citations

Transcriptional modulation of bacterial gene expression by subinhibitory concentrations of antibiotics

2002 • 519 citations

Conjugation factor of Agrobacterium tumefaciens regulates Ti plasmid transfer by autoinduction

1993 • 504 citations

Metabolism of Acyl-Homoserine Lactone Quorum-Sensing Signals by Variovorax paradoxus

2000 • 478 citations

Positive selection vectors for allelic exchange

1996 • 459 citations

The languages of bacteria

2001 • 454 citations

Regulatory cascade controls virulence in Vibrio cholerae.

1991 • 451 citations

Agrobacterium conjugation and gene regulation by N-acyl-L-homoserine lactones

1993 • 435 citations

Conditionally Replicative and Conjugative Plasmids CarryinglacZα for Cloning, Mutagenesis, and Allele Replacement in Bacteria

1996 • 431 citations

Enzymatic Synthesis of a Quorum-Sensing Autoinducer Through Use of Defined Substrates

1996 • 406 citations

Purification and Structural Identification of an Autoinducer for the Luminescence System of Vibrio harveyi

1989 • 398 citations

Induction of Rhizobium meliloti nodC expression by plant exudate requires nodD.

1985 • 392 citations

The Bases of Crown Gall Tumorigenesis

2000 • 390 citations

A genetic analysis of the function of LuxO, a two‐component response regulator involved in quorum sensing in Vibrio harveyi

1999 • 362 citations

Toxin-coregulated pilus, but not mannose-sensitive hemagglutinin, is required for colonization by Vibrio cholerae O1 El Tor biotype and O139 strains

1996 • 320 citations

Regulation of quorum sensing in Vibrio harveyi by LuxO and Sigma‐54

2000 • 313 citations

Methods for detecting acylated homoserine lactones produced by Gram-negative bacteria and their application in studies of AHL-production kinetics

2001 • 291 citations

Culture Conditions for Stimulating Cholera Toxin Production byVibrio choleraeO1 El Tor

1986 • 270 citations

Characterization of hapR, a positive regulator of the Vibrio cholerae HA/protease gene hap, and its identification as a functional homologue of the Vibrio harveyi luxR gene

1997 • 252 citations

Sequence and Function of LuxU: a Two-Component Phosphorelay Protein That Regulates Quorum Sensing in Vibrio harveyi

1999 • 245 citations

Control of the ToxR virulence regulon in Vibrio cholerae by environmental stimuli

1997 • 242 citations

Spatial control of cell differentiation in Myxococcus xanthus

2000 • 240 citations

Two-component regulator of Enterococcus faecalis cytolysin responds to quorum-sensing autoinduction

2002 • 236 citations

Control of the Competent State in Pneumococcus by a Hormone-Like Cell Product: An Example for a New Type of Regulatory Mechanism in Bacteria

1965 • 225 citations

Inhibition of Luminescence and Virulence in the Black Tiger Prawn ( Penaeus monodon ) Pathogen Vibrio harveyi by Intercellular Signal Antagonists

2000 • 224 citations

Suicide plasmids containing promoterless reporter genes can simultaneously disrupt and create fusions to target genes of diverse bacteria

1997 • 218 citations

C-factor: A cell-cell signaling protein required for fruiting body morphogenesis of M. Xanthus

1990 • 209 citations

The biocontrol strain Pseudomonas fluorescens F113 produces the Rhizobium small bacteriocin, N-(3-hydroxy-7-cis-tetradecenoyl)homoserine lactone, via HdtS, a putative novel N-acylhomoserine lactone synthase The GenBank accession number for the sequence determined in this work is AF286536.

2000 • 203 citations

AinS and a new family of autoinducer synthesis proteins

1995 • 192 citations

Quorum sensing inVibrio fischeri: elements of theluxIpromoter

1999 • 188 citations

The ins and outs of peptide signaling

1998 • 177 citations

A genetic analysis of the functions of LuxN: a two‐component hybrid sensor kinase that regulates quorum sensing in Vibrio harveyi

2000 • 175 citations

cis-acting ompF mutations that result in OmpR-dependent constitutive expression

1991 • 175 citations

Sequence and function of LuxO, a negative regulator of luminescence in Vibrio harveyi

1994 • 173 citations

Cell Alignment Required in Differentiation of Myxococcus xanthus

1990 • 155 citations

Nucleotide sequence of the regulatory locus controlling expression of bacterial genes for bioluminescence

1987 • 154 citations

News & Notes: Isolation of Vibrio harveyi from Diseased Kuruma Prawns Penaeus japonicus

1996 • 152 citations

Quorum sensing in Vibrio fischeri: evidence that S-adenosylmethionine is the amino acid substrate for autoinducer synthesis

1996 • 144 citations

In Vivo Evidence that S -Adenosylmethionine and Fatty Acid Synthesis Intermediates Are the Substrates for the LuxI Family of Autoinducer Synthases

1998 • 136 citations

Cloning and characterization of the A-factor receptor gene from Streptomyces griseus

1995 • 136 citations

Cloning and nucleotide sequence of luxR, a regulatory gene controlling bioluminescence in Vibrio harveyi

1990 • 132 citations

Identification of the C-signal, a contact-dependent morphogen coordinating multiple developmental responses inMyxococcus xanthus

2003 • 131 citations

Conservation of Intramembrane Proteolytic Activity and Substrate Specificity in Prokaryotic and Eukaryotic Rhomboids

2002 • 129 citations

Detection, purification, and structural elucidation of the acylhomoserine lactone inducer of Vibrio fischeri luminescence and other related molecules

2000 • 118 citations

Acylhomoserine Lactone Synthase Activity of the Vibrio fischeri AinS Protein

1999 • 116 citations

A conserved mechanism for extracellular signaling in eukaryotes and prokaryotes

2002 • 113 citations

Identification of a locus controlling expression of luminescence genes in Vibrio harveyi

1989 • 105 citations

Purification and properties of Myxococcus xanthus C-factor, an intercellular signaling protein.

1990 • 95 citations

Morphological Coupling in Development

2001 • 94 citations

Reversible and Specific Extracellular Antagonism of Receptor-Histidine Kinase Signaling

2002 • 88 citations

[41] Regulation of cholera toxin by temperature, pH, and osmolarity

1994 • 83 citations

Localization of protective epitopes within the pilin subunit of the Vibrio cholerae toxin-coregulated pilus

1991 • 73 citations

Providencia stuartii Genes Activated by Cell-to-Cell Signaling and Identification of a Gene Required for Production or Activity of an Extracellular Factor

1999 • 66 citations

Detection of luciferase gene sequence in nonluminescent Vibrio cholerae by colony hybridization and polymerase chain reaction

1991 • 46 citations

[4] Acylated homoserine lactone detection in pseudomonas aeruginosa Biofilms by radiolabel assay

2001 • 44 citations

Identification of Multiple ς ⁵⁴ -Dependent Transcriptional Activators in Vibrio cholerae

1998 • 44 citations