Mechanism of Intestinal Mucosal Immune Dysfunction Following Trauma–Hemorrhage: Increased Apoptosis Associated with Elevated Fas Expression in Peyer's Patches

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

Multiple Organ Failure Pathophysiology and Potential Future Therapy

1992 • 1,398 citations

Epidemiology of trauma deaths

1980 • 844 citations

The gut: a central organ after surgical stress.

1988 • 595 citations

The Role of Intestinal Barrier Failure and Bacterial Translocation in the Development of Systemic Infection and Multiple Organ Failure

1990 • 484 citations

Comparative evaluation of several DNA binding dyes in the detection of apoptosis‐associated chromatin degradation by flow cytometry

1992 • 375 citations

Effects of Parenteral and Enteral Nutrition on Gut-Associated Lymphoid Tissue

1995 • 294 citations

Gastrointestinal mucosal injury in experimental models of shock, trauma, and sepsis

1991 • 291 citations

Differential induction of apoptosis in lymphoid tissues during sepsis: variation in onset, frequency, and the nature of the mediators

1996 • 254 citations

Fas mediates apoptosis in human monocytes by a reactive oxygen intermediate dependent pathway.

1996 • 228 citations

Effect of hemorrhagic shock on bacterial translocation, intestinal morphology, and intestinal permeability in conventional and antibiotic-decontaminated rats

1990 • 222 citations

Hemorrhage Without Tissue Trauma Produces Immunosuppression and Enhances Susceptibility to Sepsis

1987 • 220 citations

Importance of apoptosis in the histopathology of drug related lesions in the large intestine.

1993 • 206 citations

Expanding the role of Peyer's patches in B-cell ontogeny

1996 • 197 citations

Cell death by apoptosis: Basic concepts and disease relevance for the gastroenterologist

1996 • 191 citations

The gut as source of sepsis after hemorrhagic shock

1988 • 180 citations

Glucocorticoid-induced apoptosis in the thymus.

1992 • 167 citations

Immunology of the intestinal tract

1993 • 142 citations

THE INDUCTION OF ACCELERATED THYMIC PROGRAMMED CELL DEATH DURING POLYMICROBIAL SEPSIS

1995 • 135 citations

Glucocorticoids and irradiation-induced apoptosis in normal murine bone marrow B-lineage lymphocytes as determined by flow cytometry.

1993 • 86 citations

Signalling and Chromatin Fragmentation in Thymocyte Apoptosis

1994 • 67 citations

APOPTOSIS AND THE IMMUNE RESPONSE

1996 • 66 citations

Intracellular signaling pathways involved in the induction of apoptosis in immature thymic T lymphocytes.

1996 • 53 citations

Hemorrhage in mice induces alterations in immunoglobulin-secreting B cells

1989 • 47 citations

Intestinal mucosal permeability to 51Cr-ethylenediaminetetraacetic acid is increased after bilateral lower extremity ischemia-reperfusion in the rat

1996 • 30 citations

Hemorrhage in mice produces alterations in intestinal B cell repertoires

1990 • 14 citations