Parameters for the molecular recognition of transfer RNAs

Structure of yeast phenylalanine tRNA at 3 Å resolution

1974 • 1,000 citations

Three-Dimensional Tertiary Structure of Yeast Phenylalanine Transfer RNA

1974 • 970 citations

Aminoacyl-tRNA Synthetases: General Features and Recognition of Transfer RNAs

1979 • 636 citations

Biochemical and physical characterization of an unmodified yeast phenylalanine transfer RNA transcribed in vitro.

1988 • 603 citations

A simple structural feature is a major determinant of the identity of a transfer RNA

1988 • 596 citations

AMINOACYL tRNA SYNTHETASES: GENERAL SCHEME OF STRUCTURE-FUNCTION RELATIONSHIPS IN THE POLYPEPTIDES AND RECOGNITION OF TRANSFER RNAS

1987 • 535 citations

Codon and amino-acid specificities of a transfer RNA are both converted by a single post-transcriptional modification

1988 • 442 citations

Changing the Identity of a tRNA by Introducing a G-U Wobble Pair Near the 3′ Acceptor End

1988 • 344 citations

Aminoacylation of RNA minihelices with alanine

1989 • 327 citations

Transfer Ribonucleic Acid-induced Hydrolysis of Valyladenylate Bound to Isoleucyl Ribonucleic Acid Synthetase

1966 • 299 citations

Changing the identity of a transfer RNA

1986 • 233 citations

Rapid Deacylation by Isoleucyl Transfer Ribonucleic Acid Synthetase of Isoleucine-specific Transfer Ribonucleic Acid Aminoacylated with Valine

1972 • 203 citations

The second genetic code

1988 • 192 citations

Modular arrangement of functional domains along the sequence of an aminoacyl tRNA synthetase

1983 • 179 citations

A novel lysine-substituted nucleoside in the first position of the anticodon of minor isoleucine tRNA from Escherichia coli.

1988 • 173 citations

Transfer ribonucleic acid synthetase catalyzed deacylation of aminoacyl transfer ribonucleic acid in the absence of adenosine monophosphate and pyrophosphate

1972 • 170 citations

More mutant tyrosine transfer ribonucleic acids

1970 • 169 citations

A single mutational modification of a tryptophan-specific transfer RNA permits aminoacylation by glutamine and translation of the codon UAG

1974 • 162 citations

On the properties and utility of a membrane filter assay in the study of isoleucyl-tRNA synthetase

1970 • 159 citations

Tyrosyl-tRNA synthetase forms a mononucleotide-binding fold

1982 • 149 citations

Construction of two Escherichia coli amber suppressor genes: tRNAPheCUA and tRNACysCUA.

1986 • 145 citations

Accuracy of in Vivo Aminoacylation Requires Proper Balance of tRNA and Aminoacyl-tRNA Synthetase

1988 • 144 citations

Changing the Acceptor Identity of a Transfer RNA by Altering Nucleotides in a "Variable Pocket"

1988 • 132 citations

Primary Structure of a Large Aminoacyl-tRNA Synthetase

1981 • 130 citations

A model of synthetase/transfer RNA interaction as deduced by protein engineering

1986 • 117 citations

15. Aminoacyl-tRNA Synthetases

1974 • 116 citations

Structural organization of complexes of transfer RNAs with aminoacyl transfer RNA synthetases

1977 • 107 citations

Phenylalanyl-tRNA Synthetase and Isoleucyl-tRNA ^Phe : A Possible Verification Mechanism for Aminoacyl-tRNA

1972 • 104 citations

Association of Transfer RNA Acceptor Identity with a Helical Irregularity

1988 • 103 citations

Analysis of Enzyme Structure and Activity by Protein Engineering

1984 • 97 citations

Actions of the anticodon arm in translation on the phenotypes of RNA mutants

1986 • 94 citations

Purification and properties of alanine tRNA synthetase from Escherichia coli A tetramer of identical subunits.

1981 • 92 citations

Mutants of Escherichia coli formylmethionine tRNA: a single base change enables initiator tRNA to act as an elongator in vitro.

1987 • 90 citations

Mischarging in mutant tyrosine transfer RNAs

1972 • 85 citations

Nucleotides that contribute to the identity of Escherichia coli tRNAPhe

1988 • 85 citations

Mutant tyrosine tRNA of altered amino acid specificity

1972 • 82 citations

Evidence for interaction of an aminoacyl transfer RNA synthetase with a region important for the identity of its cognate transfer RNA.

1988 • 80 citations

Overproduction and purification of Escherichia coli tRNAGln2 and its use in crystallization of the glutaminyl-tRNA synthetase-tRNAGln complex

1988 • 79 citations

Discrimination between glutaminyl-tRNA synthetase and seryl-tRNA synthetase involves nucleotides in the acceptor helix of tRNA.

1988 • 77 citations

Expression of synthetic suppressor tRNA genes under the control of a synthetic promoter

1986 • 73 citations

A single base pair affects binding and catalytic parameters in the molecular recognition of a transfer RNA

1989 • 73 citations

Equilibrium measurements of cognate and noncognate interactions between aminoacyl transfer RNA synthetases and transfer RNA

1975 • 68 citations

Structural homology in the amino-terminal domains of two aminoacyl-tRNA synthetases

1983 • 68 citations

Amino Acid Acceptor Stem of E. coli Suppressor tRNATyr is a Site of Synthetase Recognition

1973 • 66 citations

Valyl-tRNA synthetase gene of Escherichia coli K12. Primary structure and homology within a family of aminoacyl-TRNA synthetases.

1988 • 64 citations

Evidence that the 3'-end of a transfer RNA binds to a site in the adenylate synthesis domain of an aminoacyl-tRNA synthetase

1989 • 64 citations

Mutational alterations of tryptophan-specific transfer RNA that generate translation suppressors of the UAA, UAG and UGA nonsense codons

1974 • 64 citations

Dispensable pieces of an aminoacyl tRNA synthetase which activate the catalytic site

1984 • 62 citations

Recent Excitement in Understanding Transfer RNA Identity

1988 • 61 citations

Crystallization of a tRNA . aminoacyl-tRNA synthetase complex. Characterization and first crystallographic data.

1983 • 60 citations

Polypeptide Sequences Essential for RNA Recognition by an Enzyme

1987 • 59 citations

Mischarging single and double mutants of Escherichia coli sup3 tyrosine transfer RNA

1974 • 58 citations

Properties of a transfer RNA lacking modified nucleosides.

1988 • 55 citations

tRNA identity: A hair of the dogma that bit us

1988 • 55 citations

Sequence homologies between tonin, nerve growth factor γ-subunit, epidermal growth factor-binding protein and serine proteases

1981 • 55 citations

Specific interaction of anticodon loop residues with yeast phenylalanyl-tRNA synthetase

1982 • 54 citations

Structure-activity relationships of methionyl-tRNA synthetase: graphics modelling and genetic engineering

1987 • 52 citations

Emission Mechanism in Pulsars

1973 • 51 citations

Nucleotide substitution in the amino acid acceptor stem of lysine transfer RNA causes missense suppression

1984 • 46 citations

Two mutations in the dispensable part of alanine tRNA synthetase which affect the catalytic activity.

1985 • 46 citations

Amino Acid Replacements that Compensate for a Large Polypeptide Deletion in an Enzyme

1985 • 41 citations

Suppressor su+7 inserts tryptophan in addition to glutamine

1976 • 38 citations

Approaches to understanding the mechanism of specific protein-transfer RNA interactions

1977 • 35 citations

Identification of peptide sequences at the tRNA binding site of Escherichia coli methionyl-tRNA synthetase

1986 • 32 citations

Yeast tRNA^Asp-Aspartyl-tRNA Synthetase Complex: Low Resolution Crystal Structure

1987 • 29 citations

Selection for new codons corresponding to position 234 of the tryptophan synthetase alpha chain of Escherichia coli

1983 • 26 citations

A bacterial and silkworm aminoacyl-tRNA synthetase have a common epitope which maps to the catalytic domain of each.

1986 • 23 citations

Isolation and nucleotide sequence analysis of tRNAAlaGGC from Escherichia coli K-12

1985 • 22 citations

Mutant tyrosine transfer ribonucleic acids of Escherichia coli: Construction by recombination of a double mutant A1G82 chargeable with glutamine

1974 • 20 citations

Mischarging mutants of Su+2 glutamine tRNA in E. coli. I. Mutations near the anticodon cause mischarging.

1988 • 16 citations

Crystallization of a small fragment of an aminoacyl tRNA synthetase

1988 • 13 citations

Modification of specific lysine residues in E. coli methionyl-tRNA synthetase by crosslinking to E. coli formylmethionine tRNA

1984 • 13 citations

Modified bases and aminoacylation

1988 • 12 citations

Effect of the anticodon loop size of yeast alanyl tRNA on its biological activity

1987 • 9 citations

Mischarging mutants of Su+2 glutamine tRNA in E. coli. II. Amino acid specificities of the mutant tRNAs.

1988 • 5 citations