The Regulatory T Cell–Associated Transcription Factor FoxP3 Is Expressed by Tumor Cells

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 • 4,872 citations

N<scp>aturally</scp>A<scp>rising</scp>CD4⁺R<scp>egulatory</scp>T C<scp>ells for</scp>I<scp>mmunologic</scp>S<scp>elf</scp>-T<scp>olerance and</scp>N<scp>egative</scp>C<scp>ontrol of</scp>I<scp>mmune</scp>R<scp>esponses</scp>

2003 • 3,323 citations

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

2001 • 3,260 citations

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

2001 • 2,503 citations

Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

2005 • 2,256 citations

Regulatory T cells, tumour immunity and immunotherapy

2006 • 2,009 citations

Transient expression of FOXP3 in human activated nonregulatory CD4⁺ T cells

2006 • 973 citations

A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3

2005 • 957 citations

FOXP3: Of Mice and Men

2005 • 929 citations

Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

2007 • 836 citations

Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells

2004 • 805 citations

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

2006 • 773 citations

Regulatory T cells in cancer

2006 • 717 citations

Foxp3 Expressing CD4+CD25high Regulatory T Cells Are Overrepresented in Human Metastatic Melanoma Lymph Nodes and Inhibit the Function of Infiltrating T Cells

2004 • 680 citations

DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3⁺ conventional T cells

2007 • 658 citations

The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation.

1996 • 552 citations

Defective regulatory and effector T cell functions in patients with FOXP3 mutations

2006 • 508 citations

The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs

2005 • 439 citations

FOXP3 Is an X-Linked Breast Cancer Suppressor Gene and an Important Repressor of the HER-2/ErbB2 Oncogene

2007 • 384 citations

Foxp3 Expression in Pancreatic Carcinoma Cells as a Novel Mechanism of Immune Evasion in Cancer

2007 • 338 citations

Expression of FoxP3, a key molecule in CD4⁺CD25⁺ regulatory T cells, in adult T‐cell leukaemia/lymphoma cells

2004 • 276 citations

Antigen-specific regulatory T cells—their induction and role in infection

2004 • 237 citations

Tumor Antigen Expression in Melanoma Varies According to Antigen and Stage

2006 • 229 citations

Molecular cloning of a human melanoma-associated chondroitin sulfate proteoglycan.

1996 • 158 citations

Melan-A, A New Melanocytic Differentiation Marker

1999 • 155 citations

Vaccination against the Forkhead Family Transcription Factor Foxp3 Enhances Tumor Immunity

2007 • 146 citations

The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis

2005 • 95 citations

Splice variants of human FOXP3 are functional inhibitors of human CD4⁺ T‐cell activation

2006 • 85 citations

Lack of Foxp3 function and expression in the thymic epithelium

2007 • 76 citations

Evaluation of tumour-infiltrating CD4+CD25+FOXP3+ regulatory T cells in human cutaneous benign and atypical naevi, melanomas and melanoma metastases

2007 • 59 citations

Treatment options for post‐transplant lymphoproliferative disorder and other Epstein–Barr virus‐associated malignancies

2004 • 37 citations

Guarding the immune system: Suppression of autoimmunity by CD4⁺CD25⁺ immunoregulatory T cells

2006 • 24 citations

Absence of HER2 overexpression in metastatic malignant melanoma

2003 • 23 citations