The highly acidic C-terminal region of the yeast initiation factor subunit 2 α (eIF-2 α) contains casein kinase phosphorylation sites and is essential for maintaining normal regulation of GCN4

Methods in yeast genetics

1979 • 7,824 citations

Methods in Yeast Genetics

1988 • 4,905 citations

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1988 • 2,903 citations

[10] 5-Fluoroorotic acid as a selective agent in yeast molecular genetics

1987 • 1,375 citations

Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases

1991 • 1,327 citations

TRANSLATIONAL CONTROL IN MAMMALIAN CELLS

1991 • 1,041 citations

Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

1992 • 768 citations

Inhibition of restriction endonuclease Nel I cleavage by phosphorothioate groups and its application to oligonucleotide-directed mutagenesis

1986 • 560 citations

Acid and base hydrolysis of phosphoproteins bound to Immobilon facilitates analysis of phosphoamino acids in gel-fractionated proteins

1989 • 469 citations

PROTEINASE MUTANTS OF SACCHAROMYCES CEREVISIAE

1977 • 460 citations

Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae

1988 • 449 citations

Initiation of protein synthesis in mammalian cells

1986 • 359 citations

5′–3′ Exonucleases in phosphorothioate-based oligonucleotide-directed mutagenesis

1988 • 336 citations

Mutations at a Zn(II) finger motif in the yeast elF-2β gene alter ribosomal start-site selection during the scanning process

1988 • 283 citations

A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae.

1985 • 244 citations

Regulation of protein synthesis initiation in eucaryotes

1983 • 227 citations

Inducible expression vectors incorporating the Escherichia coli atpE translational initiation region

1987 • 227 citations

Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAI.

1989 • 197 citations

Endogenous phosphate acceptor proteins for rat liver cytosolic casein kinases.

1981 • 153 citations

Structure and regulation of eukaryotic initiation factor eIF-2. Sequence of the site in the alpha subunit phosphorylated by the haem-controlled repressor and by the double-stranded RNA-activated inhibitor

1987 • 129 citations

Post-Transcriptional Control of Gene Expression

1990 • 79 citations

Inhibition of translational initiation in Saccharomyces cerevisiae by secondary structure: the roles of the stability and position of stem‐loops in the mRNA leader

1993 • 77 citations

Role of yeast elongation factor 3 in the elongation cycle

1989 • 74 citations

A fully modular vector system for the optimization of gene expression in Escherichia coli

1991 • 69 citations

[33] Casein kinase I

1983 • 45 citations

Structure and properties of casein kinase‐2 from Saccharomyces cerevisiae

1986 • 43 citations

Casein kinase II mediates multiple phosphorylation of Saccharomyces cerevisiae eIF-2 alpha (encoded by SUI2), which is required for optimal eIF-2 function in S. cerevisiae.

1994 • 37 citations

Evidence that insulin activates casein kinase 2 in rat epididymal fat-cells and that this may result in the increased phosphorylation of an acid-soluble 22 kDa protein

1991 • 28 citations

Structural studies on the eukaryotic chain initiation factor 2 from rabbit reticulocytes and brine shrimp Artemia embryos. Phosphorylation by the heme-controlled repressor and casein kinase II.

1986 • 26 citations

Isolation and Properties of YCK2, a Saccharomyces cerevisiae Homolog of Casein Kinase-1

1993 • 22 citations

Phosphorylation of protein synthesis initiation factor-2. Identification of the site in the α-subunit phosphorylated in reticulocyte lysates

1990 • 19 citations

A comparative study of the characteristics of eIF-2 and eIF-2-ancillary factor activities from yeast Saccharomyces cerevisiae and rabbit reticulocytes.

1985 • 18 citations