Interferon alpha in combination with GM-CSF induces the differentiation of leukaemic antigen-presenting cells that have the capacity to stimulate a specific anti-leukaemic cytotoxic T-cell response from patients with chronic myeloid leukaemia
Data up to Jan 2025
Total Citations Per Year
Abstract
References (37)
The Dendritic Cell System and its Role in Immunogenicity
1991 • 4,733 citations
Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. European Group for Blood and Marrow Transplantation Working Party Chronic Leukemia [see comments]
1995 • 2,026 citations
INTERFERONS AND THEIR ACTIONS
1987 • 1,838 citations
Donor leukocyte transfusions for treatment of recurrent chronic myelogenous leukemia in marrow transplant patients
1990 • 1,544 citations
Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation.
1997 • 1,290 citations
Induction of Bystander T Cell Proliferation by Viruses and Type I Interferon in Vivo
1996 • 1,077 citations
Chronic myelocytic leukemia: Clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage
1977 • 888 citations
Enhanced NK cell activity in mice injected with interferon and interferon inducers
1978 • 735 citations
Hematologic Remission and Cytogenetic Improvement Induced by Recombinant Human Interferon AlphaAin Chronic Myelogenous Leukemia
1986 • 675 citations
Interferon Alfa-2a as Compared with Conventional Chemotherapy for the Treatment of Chronic Myeloid Leukemia
1994 • 592 citations
Marrow Transplantation for the Treatment of Chronic Myelogenous Leukemia
1986 • 566 citations
Interferon Alfa-2b Combined with Cytarabine versus Interferon Alone in Chronic Myelogenous Leukemia
1997 • 565 citations
Role of interferons and other cytokines in the regulation of the immune response
1995 • 462 citations
Bone Marrow Transplantation for Patients with Chronic Myeloid Leukemia
1986 • 422 citations
Interferon-Induced Antiviral Actions and Their Regulation
1993 • 338 citations
Use of Leukemic Dendritic Cells for the Generation of Antileukemic Cellular Cytotoxicity Against Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia
1997 • 309 citations
Production of functional IL-18 by different subtypes of murine and human dendritic cells (DC): DC-derived IL-18 enhances IL-12-dependent Th1 development
1998 • 289 citations
Interferon Alfa Versus Chemotherapy for Chronic Myeloid Leukemia: A Meta-analysis of Seven Randomized Trials
1997 • 282 citations
Interferon-α and granulocyte-macrophage colony-stimulating factor differentiate peripheral blood monocytes into potent antigen-presenting cells
1998 • 271 citations
Lymphoid Blast Crises of Chronic Myelogenous Leukemia Represent Stages in the Development of B-Cell Precursors
1983 • 215 citations
Treatment of chronic myelogenous leukemia: current status and investigational options [see comments]
1996 • 192 citations
The Dendritic Cell System And Its Role In Immunogenicity
1991 • 174 citations
Treatment of Philadelphia Chromosome-Positive Early Chronic Phase Chronic Myelogenous Leukemia With Daily Doses of Interferon Alpha and Low-Dose Cytarabine
1999 • 144 citations
Dendritic cells generated from blood precursors of chronic myelogenous leukemia patients carry the philadelphia translocation and can induce a CML-specific primary cytotoxic T-cell response
1997 • 104 citations
Generation of dendritic cells expressing bcr-abl from CD34-positive chronic myeloid leukemia precursor cells
1997 • 93 citations
Interferons And Their Actions
1987 • 91 citations
The Philadelphia chromosome translocation a paradigm for understanding leukemia
1990 • 77 citations
Treatment with interferon-alpha preferentially reduces the capacity for amplification of granulocyte-macrophage progenitors (CFU-GM) from patients with chronic myeloid leukemia but spares normal CFU-GM.
1998 • 72 citations
The Philadelphia chromosome translocation a paradigm for understanding leukemia
1990 • 65 citations
Comparative analysis of the impact of risk profile and of drug therapy on survival in CML using Sokal's index and a new score
1997 • 50 citations
Interferon-alpha and hydroxyurea in early chronic myeloid leukemia: a comparative analysis of the Italian and German chronic myeloid leukemia trials with interferon-alpha [letter]
1996 • 45 citations
GM-CSF can improve the cytogenetic response obtained with interferon-alpha therapy in patients with chronic myelogenous leukemia
1998 • 45 citations
Human Leukemia-derived Dendritic Cells: Ex-vivo Development of Specific Antileukemic Cytotoxicity
1998 • 43 citations
Generation of dendritic cells from patients with chronic myelogenous leukemia
1999 • 31 citations
Cellular immune responses to autologous chronic myelogenous leukaemia cells in vitro
1996 • 30 citations
Effect of alpha-interferons on immune function.
1997 • 29 citations
The role of type I interferons in the differentiation and function of Th1 and Th2 cells.
1997 • 23 citations