The Role of Serotonin Receptor Subtypes in the Behavioural Effects of Neuroleptic Drugs. A Paw Test Study in Rats

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.

1989 • 1,313 citations

Typical and atypical neuroleptics: differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons

1983 • 680 citations

Differential Effects of Classical and Atypical Antipsychotic Drugs on A9 and A10 Dopamine Neurons

1983 • 589 citations

Antischizophrenic Drugs and Brain Cholinergic Receptors

1974 • 474 citations

Effects of antipsychotic drugs on serotonin receptors.

1991 • 260 citations

Mechanisms of action of atypical antipsychotic drugs

1991 • 254 citations

[Biological psychiatry].

1992 • 220 citations

Typical and atypical antipsychotic occupancy of D2 and S2 receptors: An autoradiographic analysis in rat brain

1986 • 177 citations

Binding of typical and atypical antipsychotics to 5-HT1C and 5-HT2 sites: clozapine potently interacts with 5-HT1C sites

1990 • 173 citations

Serotonergic involvement with neuroleptic catalepsy

1975 • 155 citations

Treatment of schizophrenia: A clinical and preclinical evaluation of neuroleptic drugs

1993 • 132 citations

8-hydroxy-2-(di-N-propylamino) tetralin, a selective serotonin1A receptor agonist, blocks haloperidol-induced catalepsy by an action on raphe nuclei medianus and dorsalis

1988 • 126 citations

The effect of serotonergic agents on haloperidol-induced catalepsy

1990 • 118 citations

5-HT1 receptors and behavior

1992 • 114 citations

Centrally active 5-HT receptor agonists and antagonists

1992 • 112 citations

Some atypical neuroleptics inhibit [3H]SCH 23390 binding in vivo

1986 • 98 citations

The paw test: a behavioural paradigm for differentiating between classical and atypical neuroleptic drugs

1987 • 92 citations

Effects of 5-HT and 8-OH-DPAT on forebrain monoamine synthesis after local application into the median and dorsal raphe nuclei of the rat

1990 • 75 citations

Clozapine has sub-micromolar affinity for 5-HT1A receptors in human brain tissue

1992 • 64 citations

Effect of metergoline, fenfluramine, and 8-OHDPAT on catalepsy induced by haloperidol or morphine

1988 • 63 citations

Antagonism by neuroleptics of serotonin 5-HT1A and 5-HT2 receptors of normal human brain in vitro

1987 • 63 citations

Reversal of neuroleptic-induced catalepsy by novel aryl-piperazine anxiolytic drugs

1988 • 62 citations

Antagonism by 8-OH-DPAT, but not ritanserin, of catalepsy induced by SCH 23390 in the rat

1992 • 59 citations

Discriminative stimulus properties of clozapine and chlorpromazine

1978 • 58 citations

The PAW test: An animal model for neuroleptic drugs which fulfils the criteria for pharmacological isomorphism

1988 • 58 citations

The involvement of dopamine D1 and D2 receptors in the effects of the classical neuroleptic haloperidol and the atypical neuroleptic clozapine

1991 • 57 citations

Serotonergic drugs do not substitute for clozapine in clozapine-trained rats in a two-lever drug discrimination procedure

1992 • 44 citations

Effects of antipsychotic drugs on 5-HT2 receptors in the medial prefrontal cortex: microiontophoretic studies

1990 • 43 citations

Dopamine agonist activity of 8-OH-DPAT.

1990 • 33 citations

Antipsychotic‐like Properties of the 5‐HT_1A Agonist 8‐OH–DPAT in the Rat

1989 • 32 citations

Which Atypical Antipsychotics Are Identified by Screening Tests?

1989 • 32 citations

Effect of typical and atypical neuroleptic treatment on protachykinin mRNA levels in the striatum of the rat

1990 • 29 citations

Serotonergic aspects of acute extrapyramidal syndromes in nonhuman primates.

1989 • 27 citations

Separation of Calcium Isotopes by Liquid Phase Thermal Diffusion

1981 • 19 citations

Classification of neuroleptics: implications for tardive dyskinesia.

1985 • 13 citations

The role of gamma-aminobutyric acid in acute and chronic neuroleptic action.

1980 • 13 citations

The effects of haloperidol and raclopride in the paw test are influenced similarly by SCH 39166

1993 • 11 citations

ROLE OF OLFACTORY TUBERCLE AND NUCLEUS ACCUMBENS IN THE EFFECTS OF CLASSICAL AND ATYPICAL NEUROLEPTICS

1992 • 11 citations

Prefrontal cortex: Possible site of antipsychotic action of haloperidol

1986 • 10 citations