Initiation of autoimmunity to the p53 tumor suppressor protein by complexes of p53 and SV40 large T antigen.

The p53 tumour suppressor gene

1991 • 3,871 citations

T antigen is bound to a host protein in SY40-transformed cells

1979 • 2,378 citations

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1979 • 1,830 citations

Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen

1992 • 1,200 citations

Trends in the Development of Baculovirus Expression Vectors

1988 • 1,022 citations

Autoantibodies to Nuclear Antigens (ANA): Their Immunobiology and Medicine

1982 • 975 citations

Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse.

1979 • 736 citations

The Relation Between Major Histocompatibility Complex (MHC) Restriction and the Capacity of Ia to Bind Immunogenic Peptides

1987 • 696 citations

Identification, developmental regulation, and response to heat shock of two antigenically related forms of a major nuclear envelope protein in Drosophila embryos: application of an improved method for affinity purification of antibodies using polypeptides immobilized on nitrocellulose blots

1984 • 668 citations

COOPERATING AND CONTROLLING FUNCTIONS OF THYMUS-DERIVED LYMPHOCYTES IN RELATION TO AUTOIMMUNITY

1971 • 534 citations

Detection of antibodies against the cellular protein p53 in sera from patients with breast cancer

1982 • 448 citations

Monoclonal antibodies against simian virus 40 T antigens: evidence for distinct sublcasses of large T antigen and for similarities among nonviral T antigens

1980 • 430 citations

Antibody production to the nucleocapsid and envelope of the hepatitis B virus primed by a single synthetic T cell site

1987 • 319 citations

Development of antibodies against p53 in lung cancer patients appears to be dependent on the type of p53 mutation.

1992 • 299 citations

Immune response to p53 is dependent upon p53/HSP70 complexes in breast cancers.

1992 • 281 citations

The lupus autoantigens and the pathogenesis of systemic lupus erythematosus

1986 • 259 citations

Induction of autoreactive B cells allows priming of autoreactive T cells.

1991 • 253 citations

VIRAL ONCOLYSIS: INCREASED IMMUNOGENICITY OF HOST CELL ANTIGEN ASSOCIATED WITH INFLUENZA VIRUS

1967 • 234 citations

How some T cells escape tolerance induction

1989 • 216 citations

Functional analysis of influenza-specific helper T cell clones in vivo. T cells specific for internal viral proteins provide cognate help for B cell responses to hemagglutinin.

1986 • 199 citations

Virus-induced diabetes mellitus. XX. Polyendocrinopathy and autoimmunity.

1981 • 198 citations

Tumor suppressor genes

1990 • 179 citations

Breaking T cell tolerance with foreign and self co-immunogens. A study of autoimmune B and T cell epitopes of cytochrome c.

1992 • 175 citations

Epitope-directed processing of specific antigen by B lymphocytes.

1989 • 163 citations

Use of monoclonal antibodies for the characterization of novel DNA-binding proteins recognized by human autoimmune sera.

1985 • 156 citations

Heart-specific autoantibodies following murine coxsackievirus B3 myocarditis.

1985 • 148 citations

Antigenic binding sites of monoclonal antibodies specific for simian virus 40 large T antigen

1986 • 135 citations

Analysis of the anti-p53 antibody response in cancer patients.

1993 • 134 citations

The inability to process a self-peptide allows autoreactive T cells to escape tolerance.

1993 • 127 citations

Nucleolar antigens and autoantibodies in hepatocellular carcinoma and other malignancies.

1992 • 127 citations

T cells primed by influenza virion internal components can cooperate in the antibody response to haemagglutinin

1979 • 125 citations

Regulatory Mechanisms in the Immune Response to Cell-surface Antigens

1977 • 118 citations

Occurrence and significance of papovaviruses BK and JC in the urine.

1989 • 112 citations

Expression and complex formation of simian virus 40 large T antigen and mouse p53 in insect cells

1988 • 107 citations

JC papovavirus large tumor (T)-antigen expression in brain tissue of acquired immune deficiency syndrome (AIDS) and non-AIDS patients with progressive multifocal leukoencephalopathy.

1986 • 86 citations

The T cell repertoire for recognition of a phylogenetically distant protein antigen. Peptide specificity and MHC restriction of staphylococcal nuclease-specific T cell clones.

1986 • 78 citations

THE IMMUNE RESPONSE TO A HYBRID PROTEIN MOLECULE

1967 • 78 citations

Autoantibodies in infectious mononucleosis have specificity for the glycine-alanine repeating region of the Epstein-Barr virus nuclear antigen.

1987 • 74 citations

ANTINUCLEAR ANTIBODIES IN INFECTIOUS MONONUCLEOSIS

1968 • 73 citations

Fine specificity of cloned insulin-specific T cell hybridomas: evidence supporting a role for tertiary conformation.

1983 • 69 citations

Viruses as immunological adjuvants in cancer

1974 • 68 citations

T cell tolerance studied at the level of antigenic determinants. I. Latent reactivity to lysozyme peptides that lack suppressogenic epitopes can be revealed in lysozyme-tolerant mice.

1985 • 54 citations

Murine monoclonal antibodies specific for conserved and non-conserved antigenic determinants of the human and murine Ku autoantigens

1993 • 54 citations

Inoculation with BK virus may break immunological tolerance to histone and DNA antigens.

1988 • 53 citations

An immunoglobulin light chain from a lupus-prone mouse induces autoantibodies in normal mice.

1990 • 45 citations

Influence of protein-quaternary structure on antigen processing.

1993 • 38 citations

Progressive multifocal leukoencephalopathy complicating systemic lupus erythematosus

1986 • 36 citations

Passive transfer of autoimmune disease with isologous IgG1 and IgG2 antibodies to the tubular basement membrane in strain XIII guinea pigs: loss of self-tolerance induced by autoantibodies.

1977 • 36 citations

The molecular context of determinants within the priming antigen establishes a hierarchy of T cell induction: T cell specificities induced by peptides of β‐galactosidase vs. the whole antigen

1989 • 33 citations

Cell cooperation in antibody responses to influenza virus. I. Priming of helper T cells by internal components of the virion

1980 • 33 citations

Regulation of the anti-Sm autoantibody response in systemic lupus erythematosus mice by monoclonal anti-Sm antibodies.

1990 • 26 citations

Tumor suppressor genes

1991 • 18 citations

T cells specific for alpha-beta interface regions of hemoglobin recognize the isolated subunit but not the tetramer and indicate presentation without processing.

1989 • 15 citations

Analysis of a positive feedback mechanism in the anti‐Sm autoantibody response of MRL/MPJ‐lpr/lpr mice

1991 • 12 citations

ANTINUCLEAR ANTIBODIES IN INFECTIOUS MONONUCLEOSIS

1968 • 10 citations

Clinical applications of an anti-ku antigen-capture ELISA

1993 • 9 citations

Regulation of the anti-Sm autoantibody response in systemic lupus erythematosus mice by monoclonal anti-Sm antibodies.

1990 • 2 citations