Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver.

Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy.

1994 • 1,599 citations

A model system for in vivo gene transfer into the central nervous system using an adenoviral vector

1993 • 588 citations

Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice.

1993 • 531 citations

Gene therapy: adenovirus vectors

1993 • 423 citations

A mouse model for investigating the molecular pathogenesis of adenovirus pneumonia.

1991 • 348 citations

Common Control of the Heat Shock Gene and Early Adenovirus Genes: Evidence for a Cellular E1A-like Activity

1984 • 331 citations

Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1–deleted adenoviruses

1993 • 303 citations

Selection and Preliminary Characterization of Temperature-Sensitive Mutants of Type 5 Adenovirus

1972 • 248 citations

Development and Analysis of Recombinant Adenoviruses for Gene Therapy of Cystic Fibrosis

1993 • 162 citations

NF-IL6, a member of the C/EBP family, regulates E1A-responsive promoters in the absence of E1A

1992 • 95 citations

Adenovirus-mediated correction of the genetic defect in hepatocytes from patients with familial hypercholesterolemia

1993 • 87 citations