Footprinting the Sites of Interaction of Antibiotics with Catalytic Group I Intron RNA

Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis

1990 • 1,239 citations

Interaction of antibiotics with functional sites in 16S ribosomal RNA

1987 • 1,143 citations

Direct chemical method for sequencing RNA.

1979 • 940 citations

SELF-SPLICING OF GROUP I INTRONS

1990 • 852 citations

Comparison of fungal mitochondrial introns reveals extensive homologies in RNA secondary structure

1982 • 501 citations

Making ends meet: a model for RNA splicing in fungal mitochondria

1982 • 459 citations

[33] Structural analysis of RNA using chemical and enzymatic probing monitored by primer extension

1988 • 426 citations

Transfer RNA shields specific nucleotides in 16S ribosomal RNA from attack by chemical probes

1986 • 425 citations

The guanosine binding site of the Tetrahymena ribozyme

1989 • 356 citations

Secondary structure of the circular form of the Tetrahymena rRNA intervening sequence: a technique for RNA structure analysis using chemical probes and reverse transcriptase.

1985 • 315 citations

Binding of tRNA to the ribosomal A and P sites protects two distinct sets of nucleotides in 16 S rRNA

1990 • 294 citations

Antibiotic inhibition of group I ribozyme function

1991 • 259 citations

Interaction of antibiotics with A- and P-site-specific bases in 16S ribosomal RNA.

1991 • 225 citations

A Specific Amino Acid Binding Site Composed of RNA

1988 • 203 citations

New reactions of the ribosomal RNA precursor of Tetrahymena and the mechanism of self-splicing

1986 • 189 citations

RNA substrate binding site in the catalytic core of the Tetrahymena ribozyme

1992 • 182 citations

Phylogenetic and genetic evidence for base-triples in the catalytic domain of group I introns

1990 • 139 citations

Non-competitive inhibition of group I intron RNA self-splicing by aminoglycoside antibiotics

1992 • 121 citations

Evidence for processivity and two-step binding of the RNA substrate from studies of J1/2 mutants of the Tetrahymena ribozyme

1992 • 111 citations

Ribozyme inhibitors. Deoxyguanosine and dideoxyguanosine are competitive inhibitors of self-splicing of the Tetrahymena ribosomal ribonucleic acid precursor

1986 • 101 citations

Group I Intron Self-Splicing with Adenosine: Evidence for a Single Nucleoside-Binding Site

1991 • 100 citations

Mutations in a nonconserved sequence of the Tetrahymena ribozyme increase activity and specificity

1991 • 75 citations

Activation of the catalytic core of a group I intron by a remote 3' splice junction.

1992 • 62 citations

Streptomycin inhibits splicing of group I introns by competition with the guanosine substrate

1991 • 51 citations

Melting and chemical modification of a cyclized self-splicing group I intron: similarity of structures in 1 M sodium, in 10 mM magnesium and in the presence of substrate

1990 • 45 citations

The catalytic core of the sunY intron of bacteriophage T4

1989 • 14 citations

Kaposi's sarcoma and AIDS

1990 • 1 citations