A Gene in Human Chromosome Band Xq28 (GABRE) Defines a Putative New Subunit Class of the GABAANeurotransmitter Receptor

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology

1989 • 1,283 citations

Molecular biology of GABA _A receptors

1990 • 947 citations

Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels

1989 • 451 citations

Cartography of neurexins: More than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons

1995 • 446 citations

Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors.

1995 • 437 citations

GABA _A receptor subtypes: from pharmacology to molecular biology

1991 • 421 citations

Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site.

1990 • 415 citations

Insensitivity to anaesthetic agents conferred by a class of GABAA receptor subunit

1997 • 402 citations

Removal of repeated sequences from hybridisation probes

1985 • 293 citations

Reconstruction and analysis of human alu genes

1991 • 288 citations

Features of spliceosome evolution and function inferred from an analysis of the information at human splice sites

1992 • 268 citations

Benzodiazepine-induced motor impairment linked to point mutation in cerebeilar GABAA receptor

1993 • 241 citations

Identification of the cAMP-dependent protein kinase and protein kinase C phosphorylation sites within the major intracellular domains of the beta 1, gamma 2S, and gamma 2L subunits of the gamma-aminobutyric acid type A receptor.

1992 • 233 citations

Immunocytochemical Localization of the GABA_CReceptor ρ Subunits in the Mammalian Retina

1996 • 232 citations

Structural and functional characterization of the gamma 1 subunit of GABAA/benzodiazepine receptors.

1990 • 219 citations

Generation of Two Forms of the γ‐Aminobutyric Acid_A Receptor γ‐₂‐Subunit in Mice by Alternative Splicing

1991 • 196 citations

The GABAA Receptor Family: Molecular and Functional Diversity

1990 • 187 citations

Localization of the gene encoding the GABAA receptor beta 3 subunit to the Angelman/Prader-Willi region of human chromosome 15.

1991 • 177 citations

Construction, arraying, and high-density screening of large insert libraries of human chromosomes X and 21: their potential use as reference libraries.

1991 • 160 citations

γ‐Aminobutyric Acid_A Receptor Heterogeneity Is Increased by Alternative Splicing of a Novel β‐Subunit Gene Transcript

1991 • 144 citations

Structural analysis of mouse glycine receptor alpha subunit genes. Identification and chromosomal localization of a novel variant.

1994 • 136 citations

The third gamma subunit of the gamma-aminobutyric acid type A receptor family.

1992 • 129 citations

Deficiency of the β3 subunit of the type A γ–aminobutyric acid receptor causes cleft palate in mice

1995 • 122 citations

Chromosomal localization of GABAA receptor subunit genes: relationship to human genetic disease

1989 • 121 citations

A strategy for the selection of transcribed sequences in the Xq28 region

1992 • 121 citations

The Melanoma Antigen Gene (MAGE) Family Is Clustered in the Chromosomal Band Xq28

1995 • 121 citations

A strong promoter element is located between alternative exons of a gene encoding the human gamma-aminobutyric acid-type A receptor beta 3 subunit (GABRB3).

1993 • 106 citations

Molecular anatomy and molecular design of channel proteins

1990 • 104 citations

Cloning of a putative γ-aminobutyric acid (GABA) receptor subunit ϱ3 cDNA

1996 • 96 citations

The Murine GABA_AReceptor δ-Subunit Gene: Structure and Assignment to Human Chromosome 1

1990 • 91 citations

FISH ordering of reference markers and of the gene for the α5 subunit of the γ-aminobutyric acid receptor (GABRA5) within the Angelman and Prader–Willi syndrome chromosomal regions

1993 • 80 citations

Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci

1996 • 77 citations

Transcriptional organization of a 450-kb region of the human X chromosome in Xq28.

1993 • 72 citations

Small N‐Terminal Deletion by Splicing in Cerebellar α6 Subunit Abolishes GABA_A Receptor Function

1994 • 67 citations

The γ-aminobutyric acid receptor γ3 subunit gene (GABRG3) is tightly linked to the α5 subunit gene (GABRA5) on human chromosome 15q11–q13 and is transcribed in the same orientation

1995 • 66 citations

Mapping of the α4 subunit gene (GABRA4) to human chromosome 4 defines an α2—α4—β1—γ1 gene cluster: further evidence that modern GABAA receptor gene clusters are derived from an ancestral cluster

1995 • 66 citations

Mapping of the β2 Subunit Gene (GABRB2) to Microdissected Human Chromosome 5q34-q35 Defines a Gene Cluster for the Most Abundant GABAA Receptor Isoform

1994 • 62 citations

Alternative Splicing of a 51-Nucleotide Exon that Encodes a Putative Protein Kinase C Phosphorylation Site Generates Two Forms of the Chicken γ-Aminobutyric AcidAReceptor β2 Subunit

1994 • 60 citations

Molecular cloning reveals the existence of a fourth γ subunit of the vertebrate brain GABA_A receptor

1993 • 58 citations

Isolation, characterization, and localization of human genomic DNA encoding the β1 subunit of the GABAA receptor (GABRB1)

1991 • 55 citations

Localisation of the MRX3 gene for non-specific X linked mental retardation.

1991 • 53 citations

construction of a transcription map of a 300 kb region around the human G6PD locus by direst cDNA selection

1993 • 53 citations

Further Evidence for Clustering of Human GABAA Receptor Subunit Genes: Localization of the α6-Subunit Gene (GABRA6) to Distal Chromosome 5q by Linkage Analysis

1994 • 48 citations

Confirmation of the localization of the human GABAA receptor α1-subunit gene (GABRA1) to distal 5q by linkage analysis

1992 • 45 citations

Molecular biology of mammalian amino acid receptors

1990 • 43 citations

Conserved Organization of γ‐Aminobutyric Acid_AReceptor Genes: Cloning and Analysis of the Chicken β4‐Subunit Gene

1991 • 43 citations

Cloning, sequence analysis and expression of two forms of mRNA coding for the human β2 subunit of the GABAA receptor

1995 • 41 citations

A comparative transcription map of the murine bare patches (Bpa) and striated (Str) critical regions and human Xq28.

1996 • 41 citations

Linkage to Xq28 in a family with nonspecific X-linked mental retardation

1992 • 34 citations

Waisman syndrome, a human X-linked recessive basal ganglia disorder with mental retardation: Localization to Xq27.3-qter

1991 • 31 citations

An X‐linked recessive basal ganglia disorder with mental retardation

1985 • 30 citations

A 900-kb Cosmid Contig and 10 New Transcripts within the Candidate Region for Myotubular Myopathy (MTM1)

1996 • 28 citations

A YAC clone map spanning 7.5 megabases of human chromosome band Xq28

1994 • 27 citations

Transcription mapping in a 700-kb region around the DXS52 locus in Xq28: isolation of six novel transcripts and a novel ATPase isoform (hPMCA5).

1996 • 25 citations

Transcriptional analysis of the candidate region for incontinentia pigmenti (IP2) in Xq28.

1996 • 22 citations

Physical mapping by PFGE

1990 • 17 citations