Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: A sequestration mechanism in metabolic regulation

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

Manipulating the Mouse Embryo: A Laboratory Manual

2002 • 2,187 citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1991 • 1,317 citations

Dual Roles for Glucokinase in Glucose Homeostasis as Determined by Liver and Pancreatic β Cell-specific Gene Knock-outs Using Cre Recombinase

1999 • 1,284 citations

A comparison of three methods of glycogen measurement in tissues

1974 • 755 citations

Familial Hyperglycemia Due to Mutations in Glucokinase -- Definition of a Subtype of Diabetes Mellitus

1993 • 737 citations

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1996 • 728 citations

Sequence-Specific Binding of Transfer RNA by Glyceraldehyde-3-Phosphate Dehydrogenase

1993 • 461 citations

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1995 • 277 citations

Stimulation by insulin of glucokinase gene transcription in liver of diabetic rats.

1988 • 224 citations

Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects.

1996 • 215 citations

Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships.

1993 • 202 citations

Regulation of Protein Synthesis by Insulin

1994 • 198 citations

Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans.

1989 • 181 citations

Concordant Glucose Induction of Glucokinase, Glucose Usage, and Glucose-Stimulated Insulin Release in Pancreatic Islets Maintained in Organ Culture

1992 • 162 citations

Correction of diabetic alterations by glucokinase.

1996 • 151 citations

Animal Model for Maturity-onset Diabetes of the Young Generated by Disruption of the Mouse Glucokinase Gene

1995 • 135 citations

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1997 • 133 citations

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1995 • 131 citations

Transcriptional regulation of human and hamster microsomal triglyceride transfer protein genes. Cell type-specific expression and response to metabolic regulators.

1994 • 128 citations

Ribozyme-mediated attenuation of pancreatic beta-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion.

1994 • 125 citations

Expression of Human Hepatic Glucokinase in Transgenic Mice Liver Results in Decreased Glucose Levels and Reduced Body Weight

1997 • 99 citations

Species and tissue distribution of the regulatory protein of glucokinase

1993 • 82 citations

Amino Acid Conservation in Animal Glucokinases

1996 • 61 citations

Nuclear Location of the Regulatory Protein of Glucokinase in Rat Liver and Translocation of the Regulator to the Cytoplasm in Response to High Glucose

1995 • 58 citations

Genetics of NIDDM in France: Studies With 19 Candidate Genes in Affected Sib Pairs

1997 • 52 citations

Human glucokinase regulatory protein (GCKR): cDNA and genomic cloning, complete primary structure, and chromosomal localization

1995 • 44 citations

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1994 • 29 citations

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1994 • 22 citations

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