rRNA synthesis in the nucleolus

Major nucleolar proteins shuttle between nucleus and cytoplasm

1989 • 1,113 citations

Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins

1990 • 656 citations

Need for DNA topoisomerase activity as a swivel for DNA replication for transcription of ribosomal RNA

1987 • 426 citations

Transfer RNA shields specific nucleotides in 16S ribosomal RNA from attack by chemical probes

1986 • 425 citations

U3, U8 and U13 comprise a new class of mammalian snRNPs localized in the cell nucleolus.

1989 • 391 citations

Functional Cooperativity Between Transcription Factors UBF1 and SL1 Mediates Human Ribosomal RNA Synthesis

1988 • 361 citations

Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase

1990 • 344 citations

A yeast small nuclear RNA is required for normal processing of pre-ribosomal RNA.

1987 • 313 citations

A yeast nucleolar protein related to mammalian fibrillarin is associated with small nucleolar RNA and is essential for viability.

1989 • 310 citations

Functional and dynamic aspects of the mammalian nucleolus

1990 • 276 citations

Depletion of U14 small nuclear RNA (snR128) disrupts production of 18S rRNA in Saccharomyces cerevisiae.

1990 • 272 citations

A constitutive nucleolar protein identified as a member of the nucleoplasmin family.

1987 • 267 citations

Fractiontion and reconstitution of factors required for accurate transcription of mammalian ribosomal RNA genes: identification of a species-depandent initiation factor

1982 • 197 citations

Structural analysis of the human U3 ribonucleoprotein particle reveal a conserved sequence available for base pairing with pre-rRNA.

1987 • 190 citations

Purification and characterization of a transcription factor that confers promoter specificity to human RNA polymerase I.

1985 • 184 citations

Detection of a nucleolar 7-2 ribonucleoprotein and a cytoplasmic 8-2 ribonucleoprotein with autoantibodies from patients with scleroderma.

1983 • 177 citations

A Drosophila rRNA gene located in euchromatin is active in transcription and nucleolus formation.

1988 • 171 citations

The yeast homologue of U3 snRNA.

1987 • 160 citations

The RNA Processing Enzyme RNase MRP Is Identical to the Th RNP and Related to RNase P

1989 • 152 citations

An RNA polymerase I enhancer in Saccharomyces cerevisiae.

1986 • 151 citations

Isolation and sequencing of NOP1. A yeast gene encoding a nucleolar protein homologous to a human autoimmune antigen.

1990 • 136 citations

The Xenopus ribosomal gene enhancers bind an essential polymerase I transcription factor, xUBF.

1989 • 130 citations

Promoter occlusion during ribosomal RNA transcription

1988 • 123 citations

Transcription of mouse rDNA is regulated by an activated subform of RNA polymerase I

1987 • 115 citations

Characterization of factors that direct transcription of rat ribosomal DNA.

1990 • 106 citations

Growth-dependent regulation of rRNA synthesis is mediated by a transcription initiation factor (TTF-IA)

1985 • 105 citations

Specific interaction of the murine transcription termination factor TTF I with class-I RNA polymerases

1990 • 104 citations

Nucleolin from Xenopus laevis: cDNA cloning and expression during development.

1989 • 99 citations

Enhancers for RNA polymerase I in mouse ribosomal DNA.

1990 • 93 citations

Ribocharin: a nuclear Mr 40,000 protein specific to precursor particles of the large ribosomal subunit

1985 • 90 citations

Factors and nucleotide sequences that direct ribosomal DNA transcription and their relationship to the stable transcription complex.

1986 • 87 citations

The promoter-proximal rDNA terminator augments initiation by preventing disruption of the stable transcription complex caused by polymerase read-in.

1989 • 86 citations

Regulatory elements of the generic ribosomal gene

1989 • 85 citations

RNA polymerase II transcription termination is mediated specifically by protein binding to a CCAAT box sequence.

1989 • 70 citations

DNase I sensitivity of ribosomal RNA Genes in chromatin and nucleolar dominance in wheat

1988 • 69 citations

Purification and characterization of TTFI, a factor that mediates termination of mouse ribosomal DNA transcription.

1988 • 67 citations

In vitroevidence that eukaryotic ribosomal RNA transcription is regulated by modification of RNA polymerase I

1984 • 63 citations

Hormonal regulation of transcription of rDNA. Purification and characterization of the hormone-regulated transcription factor IC.

1990 • 63 citations

rUBF, an RNA polymerase I transcription factor from rats, produces DNase I footprints identical to those produced by xUBF, its homolog from frogs.

1990 • 63 citations

Hormonal regulation of transcription of rDNA: glucocorticoid effects upon initiation and elongationin vitro

1985 • 63 citations

An RNA polymerase I termination site can stimulate the adjacent ribosomal gene promoter by two distinct mechanisms in Xenopus laevis.

1990 • 61 citations

Isolation and functional characterization of TIF-IB, a factor that confers promoter specificity to mouse RNA polymerase I

1990 • 61 citations

The enhancement of ribosomal transcription by the recycling of RNA polymerase I

1987 • 52 citations

Accurate processing of human pre-rRNA in vitro.

1989 • 46 citations

A DNA-binding protein is required for termination of transcription by RNA polymerase I in Xenopus laevis.

1990 • 44 citations

A transcription factor, TFIS, interacts with both the promoter and enhancer of the Xenopus rRNA genes.

1989 • 42 citations

Sequences within the spacer region of yeast rRNA cistrons that stimulate 35S rRNA synthesis in vivo mediate RNA polymerase I-dependent promoter and terminator activities.

1989 • 36 citations

Specific transcription of Saccharomyces cerevisiae 35 S rDNA by RNA polymerase I in vitro.

1990 • 32 citations

A point mutation uncouples RNA 3'-end formation and termination during ribosomal gene transcription in Xenopus laevis.

1990 • 30 citations

Molecular analyses of the functions of SL and U3 snRNPs

1990 • 2 citations