Tumor necrosis factor ? regulation of the Fas-mediated apoptosis-signaling pathway in synovial cells

Apoptosis by Death Factor

1997 • 5,038 citations

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1995 • 4,003 citations

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

1996 • 3,065 citations

Inhibition of death receptor signals by cellular FLIP

1997 • 2,577 citations

FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis

1995 • 2,436 citations

Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death

1996 • 2,306 citations

Rheumatoid Arthritis

1990 • 1,565 citations

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)

1997 • 1,207 citations

Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α

1993 • 1,031 citations

A Novel Protein That Interacts with the Death Domain of Fas/APO1 Contains a Sequence Motif Related to the Death Domain

1995 • 1,007 citations

Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

1996 • 980 citations

FAP-1: A Protein Tyrosine Phosphatase That Associates with Fas

1995 • 702 citations

Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death.

1996 • 621 citations

Detection of tumor necrosis factor α but not tumor necrosis factor β in rheumatoid arthritis synovial fluid and serum

1988 • 570 citations

Apoptosis in rheumatoid arthritis synovium.

1995 • 378 citations

Active and latent forms of transforming growth factor beta activity in synovial effusions.

1989 • 258 citations

Tumour necrosis factor in synovial exudates.

1988 • 242 citations

Apoptosis and functional fas antigen in rheumatoid arthritis synoviocytes

1995 • 234 citations

Augmented interleukin‐1 production and hla–dr expression in the synovium of rheumatoid arthritis patients

1988 • 222 citations

Cytokines in chronic inflammatory arthritis. V. Mutual antagonism between interferon-gamma and tumor necrosis factor-alpha on HLA-DR expression, proliferation, collagenase production, and granulocyte macrophage colony-stimulating factor production by rheumatoid arthritis synoviocytes.

1990 • 214 citations

Resistance of cultured peripheral T cells towards activation‐induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death‐inducing signaling complex

1997 • 172 citations

Involvement of CPP32/Yama(-like) proteases in Fas-mediated apoptosis.

1996 • 165 citations

Activation of transcription factor NF‐κB in human synovial cells in response to tumor necrosis factor α

1996 • 139 citations

ICE/CED-3 proteasesin apoptosis

1996 • 128 citations

Therapeutic effect of the anti-Fas antibody on arthritis in HTLV-1 tax transgenic mice.

1996 • 121 citations

Induction of apoptosis in the rheumatoid synovium by Fas ligand gene transfer

1998 • 99 citations

Review: Apoptosis in rheumatoid arthritis: A novel pathway in the regulation of synovial tissue

1998 • 92 citations

Characteristics of human synovial fibroblast activation by IL-1 beta and TNF alpha.

1989 • 86 citations

CD95 (APO-1/Fas)-associating signalling proteins.

1996 • 76 citations

Expression of Fas Antigen and Fas Ligand in the Rheumatoid Synovial Tissue

1996 • 73 citations

Stimulation of human synovial fibroblast DNA synthesis by recombinant human cytokines.

1988 • 64 citations

Selective activation of the JNK/AP‐1 pathway in FAS‐mediated apoptosis of rheumatoid arthritis synoviocytes

1997 • 42 citations

Expression of basic fibroblast growth factor in synovial tissues from patients with rheumatoid arthritis: detection by immunohistological staining and in situ hybridisation.

1994 • 32 citations

Bcl-2 related proteins, apoptosis and disease.

1997 • 14 citations

Bcl-2 related proteins, apoptosis and disease

1997 • 10 citations