Nine L-type Amino Acid Residues Confer Full 1,4-Dihydropyridine Sensitivity to the Neuronal Calcium Channel α1ASubunit

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1989 • 3,067 citations

Familial Hemiplegic Migraine and Episodic Ataxia Type-2 Are Caused by Mutations in the Ca2+ Channel Gene CACNL1A4

1996 • 2,308 citations

Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the α1A-voltage-dependent calcium channel

1997 • 1,571 citations

Primary structure of the receptor for calcium channel blockers from skeletal muscle

1987 • 1,359 citations

STRUCTURE AND FUNCTION OF VOLTAGE-GATED ION CHANNELS

1995 • 941 citations

Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

1989 • 922 citations

Exocytotic Ca2+ channels in mammalian central neurons

1995 • 920 citations

Primary structure and functional expression from complementary DNA of a brain calcium channel

1991 • 871 citations

Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.

1984 • 834 citations

Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels

1993 • 614 citations

Sequence and Expression of mRNAs Encoding the α ₁ and α ₂ Subunits of a DHP-Sensitive Calcium Channel

1988 • 579 citations

Molecular Basis for CA2+ Channel Diversity

1994 • 461 citations

Calcium Channels in Vertebrate Cells

1990 • 454 citations

Distinctive biophysical and pharmacological properties of class A (BI) calcium channel α1 subunits

1993 • 431 citations

Receptor sites for Ca2+ channel antagonists

1992 • 382 citations

Primary Structure of the β Subunit of the DHP-Sensitive Calcium Channel from Skeletal Muscle

1989 • 371 citations

The naming of voltage-gated calcium channels

1994 • 360 citations

Pursuing the structure and function of voltage-gated channels

1990 • 323 citations

Antagonists of Neuronal Calcium Channels: Structure, Function, and Therapeutic Implications

1995 • 321 citations

Voltage-dependent modulation of Ca channel current in heart cells by Bay K8644.

1986 • 199 citations

Molecular properties of calcium channels

2006 • 198 citations

Cloning of the alpha 1 subunit of a voltage-dependent calcium channel expressed in pancreatic beta cells.

1992 • 195 citations

Transfer of 1,4-Dihydropyridine Sensitivity from L-Type to Class A (BI) Calcium Channels

1996 • 151 citations

Dihydropyridine receptor of L-type Ca2+ channels: identification of binding domains for [3H](+)-PN200-110 and [3H]azidopine within the alpha 1 subunit.

1991 • 144 citations

Molecular Determinants of High Affinity Phenylalkylamine Block of L-type Calcium Channels

1995 • 136 citations

The IVS6 segment of the L-type calcium channel is critical for the action of dihydropyridines and phenylalkylamines.

1996 • 122 citations

Molecular Determinants of High Affinity Dihydropyridine Binding in L-type Calcium Channels

1996 • 118 citations

Molecular localization of regions in the L-type calcium channel critical for dihydropyridine action

1993 • 106 citations

Transfer of High Sensitivity for Benzothiazepines from L-type to Class A (BI) Calcium Channels

1996 • 91 citations

Depolarization-stimulated 42K+ efflux in rat aorta is calcium- and cellular volume-dependent.

1987 • 82 citations

Calcium Binding in the Pore of L-type Calcium Channels Modulates High Affinity Dihydropyridine Binding

1995 • 82 citations

Two Amino Acid Residues in the IIIS5 Segment of L-Type Calcium Channels Differentially Contribute to 1,4-Dihydropyridine Sensitivity

1996 • 81 citations

Calcium channels from Cyprinus carpio skeletal muscle.

1991 • 70 citations

Structural Model of the Outer Vestibule and Selectivity Filter of the Shaker Voltage-gated K + Channel

1996 • 65 citations

Calcium-channel antagonists: mechanisms of action, vascular selectivities, and clinical relevance

1992 • 65 citations

Voltage- and use-dependent modulation of cardiac calcium channels by the dihydropyridine (+)-202-791.

1989 • 52 citations

Transfer of L-type Calcium Channel IVS6 Segment Increases Phenylalkylamine Sensitivity of α1A

1996 • 51 citations

Coordination of Ca2+ by the Pore Region Glutamates Is Essential for High-Affinity Dihydropyridine Binding to the Cardiac Ca2+ Channel a1 Subunit

1995 • 48 citations

Identification of Benz(othi)azepine-binding Regions within L-type Calcium Channel α1 Subunits

1996 • 43 citations

Insect calcium channels

1994 • 38 citations

L-Type Calcium Channels: Binding Domains for Dihydropyridines and Benzothiazepines Are Located in Close Proximity to Each Other

1997 • 22 citations