Coordination of Ca2+ by the Pore Region Glutamates Is Essential for High-Affinity Dihydropyridine Binding to the Cardiac Ca2+ Channel a1 Subunit

Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

1989 • 922 citations

High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment

1984 • 898 citations

Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels

1993 • 614 citations

Molecular Basis for CA2+ Channel Diversity

1994 • 461 citations

Receptor sites for Ca2+ channel antagonists

1992 • 382 citations

[3H]nitrendipine-labeled calcium channels discriminate inorganic calcium agonists and antagonists.

1982 • 265 citations

Studies on Ca channels in intact cardiac cells: voltage-dependent effects and cooperative interactions of dihydropyridine enantiomers.

1986 • 217 citations

[42] Assay for calcium channels

1985 • 191 citations

Molecular localization of ion selectivity sites within the pore of a human L-type cardiac calcium channel

1993 • 173 citations

Identification of a phenylalkylamine binding region within the alpha 1 subunit of skeletal muscle Ca2+ channels.

1990 • 171 citations

Structure and function of voltage-gated ion channels

1993 • 171 citations

Interaction of tetrandrine with slowly inactivating calcium channels. Characterization of calcium channel modulation by an alkaloid of Chinese medicinal herb origin.

1988 • 153 citations

Structural determinants of ion selectivity in brain calcium channel

1993 • 147 citations

Dihydropyridine receptor of L-type Ca2+ channels: identification of binding domains for [3H](+)-PN200-110 and [3H]azidopine within the alpha 1 subunit.

1991 • 144 citations

Calcium channels and calcium channel drugs: recent biochemical and biophysical findings.

1985 • 120 citations

Effects of metal cations and calmodulin antagonists on [3H] nitrendipine binding in smooth and cardiac muscle.

1984 • 71 citations

Calcium channels from Cyprinus carpio skeletal muscle.

1991 • 70 citations

Calcium channels: The β‐subunit increases the affinity of dihydropyridine and Ca²⁺ binding sites of the α₁‐subunit

1994 • 58 citations

A unique fluorescent phenylalkylamine probe for L-type Ca2+ channels. Coupling of phenylalkylamine receptors to Ca2+ and dihydropyridine binding sites.

1992 • 45 citations

High and low affinity states of the dihydropyridine and phenylakylamine receptors on the cardiac calcium channel and their interconversion by divalent cations

1985 • 34 citations

Characterization of [3H]nifedipine binding to intact vascular smooth muscle cells

1988 • 34 citations

Positive heterotropic allosteric regulators of dihydropyridine binding increase the Ca2+ affinity of the L-type Ca2+ channel. Stereoselective reversal by the novel Ca2+ antagonist BM 20.1140

1991 • 27 citations

Molecular Properties of Voltage-Dependent Ca<sup>2+</sup> Channels in Excitable Tissues

1993 • 26 citations

Calcium binding to extracellular sites of skeletal muscle calcium channels regulates dihydropyridine binding.

1990 • 21 citations

The devapamil‐binding site of the purified skeletal muscle receptor for organic‐calcium channel blockers is modulated by micromolar and millimolar concentrations of Ca²⁺

1991 • 17 citations

Influence of Mg++ on the effect of diltiazem to increase dihydropyridine binding to receptors on Ca++-channels in chick cardiac and skeletal muscle membranes.

1986 • 11 citations