Desmethoxyverapamil-sensitive calcium channels in rat portal vein smooth muscle

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

Specific Pharmacology of Calcium in Myocardium, Cardiac Pacemakers, and Vascular Smooth Muscle

1977 • 1,745 citations

Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells

1983 • 869 citations

Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.

1984 • 834 citations

Calcium Channels in Excitable Cell Membranes

1983 • 725 citations

Quantitative analysis of drug-receptor interactions: I. Determination of kinetic and equilibrium properties

1981 • 557 citations

Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists.

1984 • 553 citations

Antiarrhythmic Agents: The Modulated Receptor Mechanism of Action of Sodium and Calcium Channel-Blocking Drugs

1984 • 544 citations

Studies on Ca channels in intact cardiac cells: voltage-dependent effects and cooperative interactions of dihydropyridine enantiomers.

1986 • 217 citations

Characterization and photoaffinity labeling of receptor sites for the Ca2+ channel inhibitors d-cis-diltiazem, (+/-)-bepridil, desmethoxyverapamil, and (+)-PN 200-110 in skeletal muscle transverse tubule membranes.

1986 • 190 citations

Interactions of organic calcium channel antagonists with calcium channels in single frog atrial cells.

1985 • 185 citations

Different types of Ca2+ channels in mammalian skeletal muscle cells in culture.

1986 • 156 citations

Evidence for two distinct calcium channels in rat vascular smooth muscle cells in short-term primary culture

1986 • 140 citations

Excitation‐contraction coupling in voltage clamped uterine smooth muscle

1973 • 122 citations

Binding of Ca2+ entry blockers to cardiac sarcolemmal membrane vesicles. Characterization of diltiazem-binding sites and their interaction with dihydropyridine and aralkylamine receptors.

1986 • 102 citations

Dihydropyridine-sensitive Ca2+ channels in mammalian skeletal muscle cells in culture: electrophysiological properties and interactions with Ca2+ channel activator (Bay K8644) and inhibitor (PN 200-110).

1986 • 96 citations

Cat ventricular muscle treated with D600: characteristics of calcium channel block and unblock.

1984 • 95 citations

Structure and physiology of the slow inward calcium channel

1987 • 71 citations

Blocking actions of Ca2+ antagonists on the Ca2+ channels in the smooth muscle cell membrane of rabbit small intestine

1987 • 68 citations

Two types of calcium currents in single smooth muscle cells from rat portal vein.

1989 • 64 citations

Effects of calcium entry blockers on calcium‐dependent contractions of rat portal vein

1987 • 59 citations

Modeling ion channel blockade at guarded binding sites: application to tertiary drugs

1986 • 54 citations

Receptors for diphenylbutylpiperidine neuroleptics in brain, cardiac, and smooth muscle membranes. Relationship with receptors for 1,4-dihydropyridines and phenylalkylamines and with Ca2+ channel blockade

1987 • 40 citations

Characterization of the Ca2+ coordination site regulating binding of Ca2+ channel inhibitors d-cis-diltiazem, (±)bepridil and (−)desmethoxyverapamil to their receptor site in skeletal muscle transverse tubule membranes

1985 • 39 citations

The relationship between the binding site of [3H]-d-cis-diltiazem and that of other non-dihydropyridine calcium entry blockers in cardiac sarcolemma.

1987 • 24 citations

Comparison of binding affinities and calcium current inhibitory effects of a 1,4-dihydropyridine derivative (PN 200-110) in vascular smooth muscle

1988 • 21 citations

Tiapamil reduces the calcium inward current of isolated smooth muscle cells. Dependence on holding potential and pulse frequency

1986 • 18 citations

The Ca²⁺‐antagonist and binding properties of the phenylalkylamine, anipamil

1988 • 13 citations