Acrolein produces nitric oxide through the elevation of intracellular calcium levels to induce apoptosis in human umbilical vein endothelial cells: Implications for smoke angiopathy

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1991 • 6,550 citations

Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis

1992 • 4,765 citations

The pathophysiology of cigarette smoking and cardiovascular disease

2004 • 2,125 citations

Detection and Imaging of Nitric Oxide with Novel Fluorescent Indicators: Diaminofluoresceins

1998 • 1,348 citations

Nitrosylation

2001 • 1,229 citations

Protein-bound acrolein: Potential markers for oxidative stress

1998 • 622 citations

Acrolein Is a Product of Lipid Peroxidation Reaction

1998 • 521 citations

Endothelial Cell Apoptosis: Biochemical Characteristics and Potential Implications for Atherosclerosis

2001 • 445 citations

Protein‐Bound Acrolein

1999 • 394 citations

Lipid Peroxidation in Diabetes Mellitus

2004 • 372 citations

Current Status of Acrolein as a Lipid Peroxidation Product

1999 • 288 citations

Peroxynitrite and Vascular Endothelial Dysfunction in Diabetes Mellitus

2004 • 268 citations

Role of apoptosis in atherosclerosis and its therapeutic implications

2004 • 217 citations

Peroxynitrite

1998 • 181 citations

Nitric Oxide Down-regulates MKP-3 mRNA Levels

2000 • 123 citations

Role of endothelial nitric oxide synthase in endothelial activation: insights from eNOS knockout endothelial cells

2004 • 122 citations

Oxidized low density lipoprotein inhibits the migration of aortic endothelial cells in vitro.

1993 • 115 citations

Acrolein-induced cytotoxicity in cultured human bronchial epithelial cells. Modulation by alpha-tocopherol and ascorbic acid

2002 • 106 citations

Smoking and ischemic stroke: a role for nicotine?

2002 • 105 citations

Thiolation of Protein-bound Carcinogenic Aldehyde

2002 • 101 citations

Acrolein induces axolemmal disruption, oxidative stress, and mitochondrial impairment in spinal cord tissue

2003 • 99 citations

The aldehyde acrolein induces apoptosis via activation of the mitochondrial pathway

2004 • 91 citations

Peroxynitrite causes endothelial cell monolayer barrier dysfunction

2001 • 88 citations

Acrolein-Induced Cell Death In Human Alveolar Macrophages

1997 • 80 citations

Induction of thioredoxin reductase as an adaptive response to acrolein in human umbilical vein endothelial cells

2004 • 75 citations

Increased Urinary Levels of Pentosidine, Pyrraline and Acrolein Adduct in Type 2 Diabetes.

2003 • 75 citations

Induction of cellular glutathione and glutathione S-transferase by 3H-1,2-dithiole-3-thione in rat aortic smooth muscle A10 cells: protection against acrolein-induced toxicity

2003 • 70 citations

Nitric oxide prevents apoptosis of human endothelial cells from high glucose exposure during early stage

1999 • 65 citations

Cigarette Smoking and Endothelial Injury: A Review

1990 • 59 citations

Rapid Up-Regulation of Endothelial Nitric-Oxide Synthase in a Mouse Model ofEscherichia coliLipopolysaccharide-Induced Bladder Inflammation

2004 • 47 citations

Cigarette Smoking Increases Endothelial-Derived Vasorelaxation in the Rat Carotid Artery in a Dose-Dependent Manner

1997 • 37 citations

Acrolein induces Hsp72 via both PKCδ/JNK and calcium signaling pathways in human umbilical vein endothelial cells

2005 • 24 citations