Phorbol ester stimulation of prostanoid synthesis by cultured astrocytes

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Phospholipase A2 activity specific for phosphatidic acid. A possible mechanism for the production of arachidonic acid in platelets.

1981 • 368 citations

Direct activation of purified protein kinase C by unsaturated fatty acids (oleate and arachidonate) in the absence of phospholipids and Ca²⁺

1985 • 293 citations

Phorbol Ester Enhancement of Neurotransmitter Release from Rat Brain Synaptosomes

1987 • 273 citations

Astrocyte glutamate receptor activation promotes inositol phospholipid turnover and calcium flux

1986 • 187 citations

Effects of phorbol ester on catecholamine secretion and protein phosphorylation in adrenal medullary cell cultures.

1985 • 170 citations

Phorbol esters and oleoyl acetoyl glycerol enhance release of arachidonic acid in platelets stimulated by Ca2+ ionophore A23187.

1985 • 163 citations

Activation of Muscarinic and of α₁‐Adrenergic Receptors on Astrocytes Results in the Accumulation of Inositol Phosphates

1985 • 136 citations

Phorbol ester and calcium act synergistically to enhance neurotransmitter release by brain neurons in culture

1985 • 123 citations

Receptor-mediated inositol phospholipid hydrolysis in astrocytes

1986 • 112 citations

Phorbol ester facilitates 45Ca accumulation and catecholamine secretion by nicotine and excess K+ but not by muscarine in rat adrenal medulla

1986 • 112 citations

Phorbol esters reduce gonadotrope responsiveness to protein kinase C activators but not to Ca2+-mobilizing secretagogues. Does protein kinase C mediate gonadotropin-releasing hormone action?

1987 • 110 citations

An improved method for the bulk isolation of viable perikarya from postnatal cerebellum

1981 • 107 citations

Arachidonic Acid Release and Catecholamine Secretion from Digitonin‐Treated Chromaffin Cells: Effects of Micromolar Calcium, Phorbol Ester, and Protein Alkylating Agents

1985 • 97 citations

Role of phospholipase C and protein kinase C in vasoconstrictor-induced prostaglandin synthesis in cultured rat renal mesangial cells

1986 • 75 citations

Synergistic stimulation of thromboxane biosynthesis by calcium ionophore and phorbol ester or thrombin in human platelets

1985 • 70 citations

Eicosanoid synthesis and release from primary cultures of rat central nervous system astrocytes and meningeal cells

1985 • 69 citations

Adrenergic modulation of vascular prostacyclin (PGI2) secretion

1985 • 63 citations

Comparison of the prostanoid synthesizing capacity in homogenates from primary neuronal and astroglial cell cultures

1984 • 53 citations

Cholinergic stimulation of arachidonic acid and phosphatidic acid metabolism in C62B glioma cells.

1986 • 52 citations

Norepinephrine-stimulated vascular prostacyclin synthesis. Receptor-dependent calcium channels control prostaglandin synthesis

1984 • 42 citations

The effects of alpha1-adrenergic and muscarinic cholinergic stimulation on prostaglandin release by rabbit iris

1984 • 33 citations

The effect of nifedipine, nimodipine and nisoldipine on agonistand trauma-stimulated vascular prostacyclin synthesis in vitro

1986 • 32 citations

Prostanoid synthesis by the rat urinary bladder: evidence for stimulation through muscarine receptor-linked calcium channels

1986 • 32 citations

1-oleoyl-2-acetyl-glycerol and phorbol diester stimulate Ca2+ influx through Ca2+ channels in neuroblastoma × glioma hybrid NG108-15 cells

1986 • 29 citations

Internal architecture of the core nucleosome: fluorescence energy transfer studies at methionine-84 of histone H4

1986 • 29 citations

The role of the diacylglycerol-protein kinase C system in mediating adrenoceptor-prostacyclin synthesis coupling in the rat aorta

1987 • 29 citations

Evidence for an interaction between GABAB and glutamate receptors in astrocytes as revealed by changes in Ca2+ flux

1986 • 27 citations

Calcium entry into cultured mouse astrocytes

1986 • 27 citations

Muscarinic stimulation of prostacyclin synthesis by the rat penis

1986 • 25 citations

Inositol phospholipids are probably not the source of arachidonic acid for eicosanoid synthesis in astrocytes

1987 • 23 citations

Calcium ionophore A23187 primes human B-cells for activation by phorbol dibutyrate by converting receptors for phorbol dibutyrate from a low to high affinity state

1986 • 14 citations