A consonant model of the tRNA-ribosome complex during the elongation cycle of translation

Structure, Function, and Genetics of Ribosomes

1986 • 852 citations

Intermediate states in the movement of transfer RNA in the ribosome

1989 • 736 citations

POSTTRANSCRIPTIONAL REGULATORY MECHANISMS IN ESCHERICHIA COLI

1988 • 670 citations

The ribosome: Structure, function and evolution

1991 • 531 citations

Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites

1989 • 492 citations

Transfer RNA shields specific nucleotides in 16S ribosomal RNA from attack by chemical probes

1986 • 425 citations

Nucleic Acid-Protein Recognition

1977 • 343 citations

Model for the three-dimensional folding of 16 S ribosomal RNA

1988 • 306 citations

A detailed model of the three-dimensional structure of Escherichia coli 16 S ribosomal RNA in situ in the 30 S subunit

1988 • 284 citations

A Complete Mapping of the Proteins in the Small Ribosomal Subunit of Escherichia coli

1987 • 275 citations

Binding of transfer ribonucleic acid to ribosomes engaged in protein synthesis: Number and properties of ribosomal binding sites

1965 • 169 citations

Photo-affinity labelling at the peptidyl transferase centre reveals two different positions for the A- and P-sites in domain V of 23S rRNA.

1988 • 118 citations

A model for the spatial arrangement of the proteins in the large subunit of the Escherichia coli ribosome.

1988 • 115 citations

High resolution localization of the tRNA anticodon interaction site on the Escherichia coli 30 S ribosomal subunit.

1984 • 107 citations

Quantitative study of interaction of deacylated tRNA with Escherichia coli ribosomes

1983 • 105 citations

70-S Ribosomes of Escherichia coli Have an Additional Site for Deacylated tRNA Binding

2005 • 103 citations

Site-directed cross-linking of mRNA analogues to theEscherichia coliribosome; Identification of 30S rlbosomal components that can be cross-linked to the mRNA at various points 5′ withrespect to the decoding site

1989 • 99 citations

tRNA binding sites of ribosomes from Escherichia coli

1984 • 94 citations

Selective isolation and detailed analysis of intra-RNA cross-links induced in the large ribosomal subunit of E. coli: a model for the tertiary structure of the tRNA binding domain in 23S RNA

1990 • 85 citations

Cross-linking of initiation factor IF-2 to Escherichia coli 30 S ribosomal proteins with dimethylsuberimidate

1975 • 82 citations

Localisation of a series of intra–RNA cross-links in the secondary and tertiary structure of 23S RNA, induced by ultraviolet irradiation ofEscherichia50S ribosomal subunits

1983 • 77 citations

Localization of elongation factor Tu on the ribosome

1986 • 72 citations

Immunoelectron microscopic localization of puromycin binding on the large subunit of the Escherichia coli ribosome.

1982 • 69 citations

Significance of the third tRNA binding site, the E site, on E. coli ribosomes for the accuracy of translation: an occupied E site prevents the binding of non-cognate aminoacyl-tRNA to the A site.

1990 • 68 citations

Cross-linking of initiation factor IF3 to proteins of the Escherichia coli 30 S ribosomal subunit

1976 • 64 citations

The Sequence of Reactions leading to the Synthesis of a Peptide Bond on Reticulocyte Ribosomes

1969 • 54 citations

Further Studies on Bacterial Polypeptide Elongation

1969 • 51 citations

Elongation factor Tu localized on the exterior surface of the small ribosomal subunit

1986 • 48 citations

Messenger RNA orientation on the ribosome. Placement by electron microscopy of antibody-complementary oligodeoxynucleotide complexes.

1988 • 47 citations

Three-dimensional reconstruction of the ribosome from Escherichia coli

1989 • 45 citations

Comparative cross-linking study on the 50S ribosomal subunit from Escherichia coli

1989 • 40 citations

Photochemical cross-linking of yeast tRNAPhe containing 8-azidoadenosine at positions 73 and 76 to the Escherichia coli ribosome

1988 • 39 citations

Location of tRNA on the ribosome

1983 • 34 citations

Formation and properties of a covalent complex between elongation factor Tu and Phe-tRNA bearing a photoaffinity probe on its 3-(3-amino-3-carboxypropyl)uridine residue

1983 • 31 citations

Structural arrangement of the decoding site of Escherichia coli ribosomes as revealed from the data on affinity labelling of ribosomes by analogs of mRNA - derivatives of oligoribonucleotides

1990 • 30 citations

Preparation of 2‐azidoadenosine 3′,5′‐[5′‐³²P]bisphosphate for incorporation into transfer RNA Photoaffinity labeling of Escherichia coli ribosomes

1989 • 27 citations

Polynucleotide—Protein Cross-Links Induced by Ultraviolet Light and Their Use for Structural Investigation of Nucleoproteins

1989 • 26 citations

Crosslinking of phenylalanyl-tRNA to the ribosomal A site via a photoaffinity probe attached to the 4-thiouridine residue is exclusively to ribosomal protein S19

1984 • 26 citations

Ribosomal proteins S7 and L1 are located close to the decoding site ofE.coliribosome — affinity labeling studies with modified tRNAs carrying photoreactive probes attached adjacent to the 3′-end of the anticodon

1989 • 26 citations

Photosensitized cross‐linking of IF‐3 to Escherichia coli 30 S subunits

1977 • 24 citations

The effect of guanylyl-5′-methylene diphosphonate on binding of aminoacyl-transfer ribonucleic acid to ribosomes

1971 • 24 citations

Photoaffinity labelling of Escherichia coli ribosomes

1987 • 22 citations

Probing tRNA binding sites on the Escherichia coli 30 S ribosomal subunit with photoreactive analogs of the anticodon arm

1990 • 22 citations

Crosslinking of N‐Acetyl‐phenylalanyl [s⁴U]tRNA^Phe to Protein S10 in the Ribosomal P Site

1982 • 20 citations

[23] Affinity labeling of ribosomes

1988 • 18 citations

Nucleotide residues of tRNA, directly interacting with proteins within the complex of the 30 S subunit of E. coli ribosome with poly(U) and NAcPhe‐tRNA^Phe

1989 • 18 citations

Photosensitized crosslinking of tRNA to the P-, A- and R-sites of Escherichia coli ribosomes

1982 • 16 citations

Determination of tRNA nucleotide residues directly interacting with proteins in the post‐ and pretranslocated ribosomal complexes

1990 • 13 citations

Three‐dimensional location of ribosomal protein BL2 from Bacillus stearothermophilus, a key component of the peptidyl transferase center

1988 • 13 citations

Structural characteristics and classfication of some tRNA‐binding sites of elongating Escherichia coli ribosome

1986 • 13 citations

Negatively stained 50 S ribosomal subunits of Escherichia coli

1986 • 13 citations

Chemical conversion of cytidine residues into 4-thiouridines in yeast tRNA^Phe. Determination of the modified cytidines

1984 • 11 citations