Significance of the third tRNA binding site, the E site, on E. coli ribosomes for the accuracy of translation: an occupied E site prevents the binding of non-cognate aminoacyl-tRNA to the A site.

Isolation and characterization of ribonuclease I mutants of Escherichia coli

1966 • 495 citations

Polypeptide synthesis in Escherichia coli

1963 • 371 citations

The behaviour of acetylphenylalanyl soluble ribonucleic acid in polyphenylalanine synthesis

1966 • 323 citations

Genomic organization and physical mapping of the transfer RNA genes in Escherichia coli K12

1990 • 311 citations

Nucleoside triphosphate regeneration decreases the frequency of translation errors.

1979 • 294 citations

Codon-specific missense errors in vivo.

1983 • 178 citations

A simplified procedure for the isolation of bacterial polypeptide elongation factor EF-Tu

1980 • 168 citations

[45] Parameters for the preparation of Escherichia coli ribosomes and ribosomal subunits active in tRNA binding

1988 • 132 citations

The allosteric three-site model for the ribosomal elongation cycle

1989 • 126 citations

Allosteric interactions between the ribosomal transfer RNA-binding sites A and E.

1986 • 87 citations

[44] Mg2+/NH4+/polyamine system for polyuridine-dependent polyphenylalanine synthesis with near in vivo characteristics

1988 • 73 citations

Destabilization of codon-anticodon interaction in the ribosomal exit site

1987 • 70 citations

Ribosome editing and the error catastrophe hypothesis of cellular aging

1977 • 59 citations

A multiple mutant of Escherichia coli lacking the exoribonucleases RNase II, RNase D, and RNase BN.

1984 • 54 citations

Specific recognition of the 3′-terminal adenosine of tRNAPhe in the exit site of Escherichia coli ribosomes

1988 • 53 citations

Spontaneous, elongation factor G independent translocation of Escherichia coli ribosomes.

1983 • 52 citations

Codon-anticodon interaction at the ribosomal E site.

1986 • 51 citations

Mutations in ribosomal proteins L7/L12 perturb EF-G and EF-Tu functions

1988 • 48 citations

[54] Isolation of the protein synthesis elongation factors EF-Tu, EF-Ts, and EF-G from Escherichia coli

1979 • 39 citations

Is translation inhibited by noncognate ternary complexes?

1988 • 29 citations

Tests of the ribosome editor hypothesis

1983 • 29 citations

Mistranslation in twelve Escherichia coli ribosomal proteins. Cysteine misincorporation at neutral amino acid residues other than tryptophan

1987 • 25 citations

Counting cycles of EF-Tu to measure proofreading in translation

1986 • 21 citations

The role of translocation in ribosomal accuracy. Translocation rates for cognate and noncognate aminoacyl- and peptidyl-tRNAs on Escherichia coli ribosomes.

1987 • 13 citations

Nonenzymic translocation and spontaneous release of noncognate peptidyl transfer ribonucleic acid from Escherichia coli ribosomes

1980 • 10 citations