Determination of Residues in the Norepinephrine Transporter That Are Critical for Tricyclic Antidepressant Affinity

Neurotransmitter Transporters: Recent Progress

1993 • 1,089 citations

Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter

1991 • 928 citations

Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.

1993 • 883 citations

Cloning and expression of a functional serotonin transporter from rat brain

1991 • 822 citations

Cloning of a Serotonin Transporter Affected by Antidepressants

1991 • 613 citations

Cloning and Expression of a Cocaine-Sensitive Rat Dopamine Transporter

1991 • 587 citations

Cloning and Expression of a Cocaine-Sensitive Dopamine Transporter Complementary DNA

1991 • 584 citations

Molecular characterization of the dopamine transporter

1993 • 560 citations

Blockade by antidepressants and related compounds of biogenic amine uptake into rat brain synaptosomes: Most antidepressants selectively block norepinephrine uptake

1984 • 528 citations

Inhibition of Uptake of Tritiated-noradrenaline in the Intact Rat Brain by Imipramine and Structurally Related Compounds

1964 • 506 citations

Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter.

1992 • 467 citations

Catecholamine uptake by synaptosomes in homogenates of rat brain: stereospecificity in different areas.

1969 • 445 citations

Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding.

1992 • 393 citations

Stable expression of biogenic amine transporters reveals differences in inhibitor sensitivity, kinetics, and ion dependence.

1994 • 375 citations

Cloning and functional characterization of a cocaine‐sensitive dopamine transporter

1991 • 362 citations

Delineation of discrete domains for substrate, cocaine, and tricyclic antidepressant interactions using chimeric dopamine-norepinephrine transporters.

1994 • 326 citations

Cloning of the cocaine-sensitive bovine dopamine transporter.

1991 • 261 citations

Chimeric dopamine-norepinephrine transporters delineate structural domains influencing selectivity for catecholamines and 1-methyl-4-phenylpyridinium.

1994 • 237 citations

Channels in transporters

1996 • 232 citations

Uptake mechanisms for neurotransmitter amines

1974 • 217 citations

Cloning, expression, and localization of a chloride-facilitated, cocaine-sensitive serotonin transporter from Drosophila melanogaster.

1994 • 181 citations

A cocaine-sensitive Drosophila serotonin transporter: cloning, expression, and electrophysiological characterization.

1994 • 179 citations

Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium

1993 • 171 citations

Inability to N-glycosylate the human norepinephrine transporter reduces protein stability, surface trafficking, and transport activity but not ligand recognition.

1996 • 169 citations

External Cysteine Residues in the Serotonin Transporter

1997 • 158 citations

The Caenorhabditis elegans gene T23G5.5 encodes an antidepressant- and cocaine-sensitive dopamine transporter.

1998 • 153 citations

Structural domains of catecholamine transporter chimeras involved in selective inhibition by antidepressants and psychomotor stimulants.

1995 • 133 citations

THE METABOLISM, STORAGE, AND RELEASE OF CATECHOLAMINES.

1965 • 127 citations

Chimeric human and rat serotonin transporters reveal domains involved in recognition of transporter ligands.

1994 • 125 citations

Cloning and expression of the bovine sodium‐ and chloride‐dependent noradrenaline transporter

1994 • 116 citations

Transporter explosion: update on uptake

1992 • 110 citations

Antipeptide Antibodies Confirm the Topology of the Human Norepinephrine Transporter

1995 • 108 citations

N‐Linked Oligosaccharides Are Required for Cell Surface Expression of the Norepinephrine Transporter but Do Not Influence Substrate or Inhibitor Recognition

1996 • 104 citations

Dopamine transporter mutants selectively enhance MPP⁺ transport

1993 • 100 citations

An Extracellular Loop Region of the Serotonin Transporter May Be Involved in the Translocation Mechanism

1997 • 97 citations

Patch-clamp and amperometric recordings from norepinephrine transporters: Channel activity and voltage-dependent uptake

1998 • 96 citations

Single-channel currents produced by the serotonin transporter and analysis of a mutation affecting ion permeation

1996 • 91 citations

Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with the human serotonin transporter.

1996 • 88 citations

The rat norepinephrine transporter: molecular cloning from PC12 cells and functional expression

1997 • 86 citations

The in situ size of the dopamine transporter is a tetramer as estimated by radiation inactivation

1994 • 83 citations

Dopamine Transporter Cysteine Mutants: Second Extracellular Loop Cysteines Are Required for Transporter Expression

1995 • 67 citations

A single serine residue controls the cation dependence of substrate transport by the rat serotonin transporter

1997 • 65 citations

Radiation inactivation studies of the dopamine reuptake transporter protein.

1994 • 41 citations

Molecular Cloning and Characterization of anl-Epinephrine Transporter from Sympathetic Ganglia of the Bullfrog,Rana catesbiana

1997 • 30 citations

The Rat Serotonin Transporter: Identification of Cysteine Residues Important for Substrate Transport

1997 • 23 citations