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INHIBITION OF HUMAN DENDRITIC CELL FUNCTIONS BY METHYLPREDNISOLONE

Data up to Jan 2025

Published1999
Citations85
References34

Total Citations Per Year

Abstract

References (34)

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

CD28/B7 SYSTEM OF T CELL COSTIMULATION

1996 • 2,726 citations

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

1995 • 2,531 citations

Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis

1995 • 2,386 citations

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

1996 • 2,032 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

Origin, maturation and antigen presenting function of dendritic cells

1997 • 1,375 citations

Activation of human dendritic cells through CD40 cross-linking.

1994 • 1,351 citations

CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells.

1996 • 1,105 citations

Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo.

1996 • 800 citations

Expression of relB is required for the development of thymic medulla and dendritic cells

1995 • 794 citations

Glucocorticoid Therapy for Immune-Mediated Diseases: Basic and Clinical Correlates

1993 • 762 citations

Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily.

1995 • 756 citations

Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: evidence for a soluble CD14-dependent pathway.

1997 • 443 citations

Expression and function of OX40 ligand on human dendritic cells.

1997 • 416 citations

Corticosteroids inhibit IL-12 production in human monocytes and enhance their capacity to induce IL-4 synthesis in CD4+ lymphocytes.

1997 • 349 citations

Regulation of cytokine and cytokine receptor expression by glucocorticoids

1996 • 326 citations

The endocytic activity of dendritic cells.

1995 • 308 citations

Measles Virus Infects Human Dendritic Cells and Blocks Their Allostimulatory Properties for CD4+ T Cells

1997 • 274 citations

Glucocorticoid receptor-mediated suppression of the interleukin 2 gene expression through impairment of the cooperativity between nuclear factor of activated T cells and AP-1 enhancer elements.

1992 • 246 citations

Interleukin‐10 prevents the generation of dendritic cells from human peripheral blood mononuclear cells cultured with interleukin‐4 and granulocyte/ macrophage‐colony‐stimulating factor

1997 • 244 citations

Corticosteroids Enhance the Capacity of Macrophages to Induce Th2 Cytokine Synthesis in CD4+ Lymphocytes by Inhibiting IL-12 Production

1998 • 240 citations

Glucocorticoids down‐regulate dendritic cell function in vitro and in vivo

1995 • 220 citations

Human dendritic cell responses to lipopolysaccharide and CD40 ligation are differentially regulated by interleukin‐10

1997 • 210 citations

Inhibition by glucocorticoids of the formation of interleukin-1 alpha, interleukin-1 beta, and interleukin-6: mediation by decreased mRNA stability.

1993 • 202 citations

Nuclear localization of RelB is associated with effective antigen-presenting cell function.

1997 • 137 citations

Glucocorticoid modulation of human monocyte/macrophage function: Control of TNF-α secretion

1997 • 117 citations

Coexpression of NF-kappa B/Rel and Sp1 transcription factors in human immunodeficiency virus 1-induced, dendritic cell-T-cell syncytia.

1995 • 115 citations

TRENDS IN THE USE OF GLUCOCORTICOIDS IN RENAL TRANSPLANTATION

1994 • 108 citations

A novel mechanism of glucocorticoid-induced immune suppression: the inhibiton of T cell-mediated terminal maturation of a murine dendritic cell line.

1996 • 99 citations

TRENDS IN THE USE OF GLUCOCORTICOIDS IN RENAL TRANSPLANTATION

1994 • 94 citations

Regulation of CD40 ligand expression on naive CD4 T cells: a role for TCR but not co-stimulatory signals

1996 • 83 citations

Differential nuclear localization of p50, p52, and RelB proteins in human accessory cells of the immune response in situ

1996 • 51 citations

Clinical use of inhaled corticosteroids in asthma

1996 • 18 citations

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INHIBITION OF HUMAN DENDRITIC CELL FUNCTIONS BY METHYLPREDNISOLONE (1999) – Transplantation | Metascience Observatory Explorer