Paradoxical cAMP-Induced Lung Endothelial Hyperpermeability Revealed by Pseudomonas aeruginosa ExoY

The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species.

1989 • 1,393 citations

Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells.

1982 • 929 citations

Microvascular Permeability

1999 • 769 citations

Regulation of endothelial cell gap formation and barrier dysfunction: Role of myosin light chain phosphorylation

1995 • 550 citations

ExoY, an adenylate cyclase secreted by thePseudomonas aeruginosatype III system

1998 • 438 citations

The exoenzyme S regulon of Pseudomonas aeruginosa

1997 • 368 citations

Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury

1999 • 351 citations

A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell

2001 • 282 citations

Cyclic Nucleotide–Gated Channels Colocalize with Adenylyl Cyclase in Regions of Restricted Camp Diffusion

2000 • 266 citations

Role of cyclic adenosine monophosphate in the induction of endothelial barrier properties

1989 • 251 citations

Differential effect of MLC kinase in TNF-α-induced endothelial cell apoptosis and barrier dysfunction

2001 • 216 citations

THE PROPERTIES OF AN ADENINE RIBONUCLEOTIDE PRODUCED WITH CELLULAR PARTICLES, ATP, Mg⁺⁺, AND EPINEPHRINE OR GLUCAGON

1957 • 204 citations

Purification of Factor I and Recognition of a Third Factor of the Anthrax Toxin

1961 • 202 citations

CYTOCHEMICAL LOCALIZATION OF ADENYL CYCLASE ACTIVITY IN RAT ISLETS OF LANGERHANS

1972 • 168 citations

Bacillus anthracis calmodulin-dependent adenylate cyclase: chemical and enzymatic properties and interactions with eucaryotic cells.

1984 • 165 citations

Generation and Characterization of a Protective Monoclonal Antibody toPseudomonas aeruginosaPcrV

2002 • 161 citations

Signal transduction and regulation of lung endothelial cell permeability. Interaction between calcium and cAMP

1998 • 150 citations

The family of bacterial ADP-ribosylating exotoxins

1995 • 149 citations

Microvascular permeability and number of tight junctions are modulated by cAMP

1998 • 144 citations

Extracytoplasmic adenylate cyclase of Bordetella pertussis.

1976 • 144 citations

Regulation of the Ca2+-inhibitable Adenylyl Cyclase Type VI by Capacitative Ca2+ Entry Requires Localization in Cholesterol-rich Domains

2000 • 128 citations

Biological Effects of Pseudomonas aeruginosa Type III-Secreted Proteins on CHO Cells

1999 • 127 citations

The effect of histamine and cyclic adenosine monophosphate on myosin light chain phosphorylation in human umbilical vein endothelial cells.

1993 • 122 citations

Role of myosin light-chain phosphorylation in endothelial cell retraction

1993 • 117 citations

Transcriptional analysis of the Pseudomonas aeruginosa exoenzyme S structural gene

1995 • 107 citations

Control of cAMP in lung endothelial cell phenotypes. Implications for control of barrier function

1999 • 107 citations

Regulation of Endothelial Barrier Function by the cAMP-Dependent Protein Kinase

2000 • 107 citations

Residence of Adenylyl Cyclase Type 8 in Caveolae Is Necessary but Not Sufficient for Regulation by Capacitative Ca2+Entry

2002 • 93 citations

Dominant regulation of interendothelial cell gap formation by calcium-inhibited type 6 adenylyl cyclase

2002 • 91 citations

Ca(2+)-inhibitable adenylyl cyclase modulates pulmonary artery endothelial cell cAMP content and barrier function.

1995 • 83 citations

Pathologic features of pseudomonal pneumonia.

1967 • 79 citations

Mechanisms of Cholera Toxin Prevention of Thrombin- and PMA-Induced Endothelial Cell Barrier Dysfunction

1994 • 78 citations

Pharmacological modification of pulmonary vascular injury: possible role of cAMP

1987 • 72 citations

Critical involvement of p38 MAP kinase in pertussis toxin‐induced cytoskeletal reorganization and lung permeability

2002 • 70 citations

Coordinate regulation of membrane cAMP by Ca²⁺-inhibited adenylyl cyclase and phosphodiesterase activities

2003 • 57 citations

cAMP protects endothelial barrier function independent of inhibiting MLC₂₀-dependent tension development

1998 • 55 citations

Ca(2+)-inhibitable adenylyl cyclase and pulmonary microvascular permeability

1997 • 54 citations

The chemical basis of the virulence of Bacillus anthracis. IV. Secondary shock as the major factor in death of guinea-pigs from anthrax.

1955 • 52 citations

Update on Pulmonary Edema: the Role and Regulation of Endothelial Barrier Function

2001 • 48 citations

Effects of dibutyryl cAMP on pulmonary air embolism-induced lung injury in awake sheep

1987 • 33 citations

Pulmonary microvascular injury induced by Pseudomonas aeruginosa cytotoxin in isolated rabbit lungs

1986 • 28 citations

Cytochemical localization of adenylate cyclase in cultured renal epithelial (A6) cells

1998 • 8 citations