Activin inhibition of prostate cancer cell growth: selective actions on androgen-responsive LNCaP cells.

TGFβ signals through a heteromeric protein kinase receptor complex

1992 • 1,519 citations

Inhibins, Activins, and Follistatins: Gonadal Proteins Modulating the Secretion of Follicle-Stimulating Hormone

1988 • 826 citations

Expression of Transforming Growth Factor-β in the Rat Ventral Prostate during Castration-Induced Programmed Cell Death

1989 • 417 citations

Direct mitogenic effects of insulin, epidermal growth factor, glucocorticoid, cholera toxin, unknown pituitary factors and possibly prolactin, but not androgen, on normal rat prostate epithelial cells in serum-free, primary cell culture.

1984 • 315 citations

Activin Receptors and Cellular Signaling by the Receptor Serine Kinase Family

1994 • 259 citations

Primary structure of the human follistatin precursor and its genomic organization.

1988 • 234 citations

Follistatin and Activin: A Potential Intrinsic Regulatory System within Diverse Tissues

1991 • 232 citations

Activin-Binding Protein Is Present in Pituitary*

1991 • 222 citations

Activin induces cell death in hepatocytes in vivo and in vitro

1993 • 206 citations

Activin A: an autocrine inhibitor of initiation of DNA synthesis in rat hepatocytes.

1993 • 205 citations

Genetic change in transforming growth factor beta (TGF-beta) receptor type I gene correlates with insensitivity to TGF-beta 1 in human prostate cancer cells.

1996 • 195 citations

Identification of a Cellular Receptor for Transforming Growth Factor-β in Rat Ventral Prostate and Its Negative Regulation by Androgens*

1988 • 178 citations

Structural Characterization of Follistatin: A Novel Follicle-Stimulating Hormone Release-Inhibiting Polypeptide from the Gonad

1987 • 176 citations

Follistatin Gene Expression in the Ovary and Extragonadal Tissues

1989 • 175 citations

Chloromethyl ketones block induction of nitric oxide synthase in murine macrophages by preventing activation of nuclear factor-kappa B.

1995 • 167 citations

Differential effects of transforming growth factor β on human prostate cancer cells in vitro

1989 • 166 citations

Inhibition of vascular endothelial cell growth by activin-A.

1993 • 157 citations

Rat follistatin: Gonadal and extragonadal expression and evidence for alternative splicing

1990 • 153 citations

Comparison of [3H]thymidine incorporation with MTT- and MTS-based bioassays for human and murine IL-2 and IL-4 analysis Tetrazolium assays provide markedly enhanced sensitivity

1995 • 145 citations

Gonadal tumorigenesis in transgenic mice bearing the mouse inhibin alpha-subunit promoter/simian virus T-antigen fusion gene: characterization of ovarian tumors and establishment of gonadotropin-responsive granulosa cell lines.

1995 • 138 citations

Identification and characterization of binding proteins for inhibin and activin in human serum and follicular fluids.

1993 • 112 citations

Activin-A, Inhibin and Transforming Growth Factor-β Modulate Growth of Two Gonadal Cell Lines*

1989 • 100 citations

Characterization of the potentiation effect of activin on human erythroid colony formation in vitro

1989 • 71 citations

Expression of type II activin receptor genes in the male and female reproductive tissues of the rat.

1993 • 71 citations

Characterization of gonadal sex cord-stromal tumor cell lines from inhibin-alpha and p53-deficient mice: the role of activin as an autocrine growth factor.

1994 • 69 citations

Transgenic models for the study of prostate cancer

1993 • 49 citations

Modulation of Sensitivity to Transforming Growth Factor-β1 (TGF-β1) and the Level of Type II TGF-β Receptor in LNCaP Cells by Dihydrotestosterone

1996 • 45 citations

Differential expression of inhibin subunits and follistatin, but not of activin receptor type II, during early murine embryonic development

1992 • 40 citations

Mitogenic effects and nuclear localisation of procorticotrophin-releasing hormone expressed within stably transfected fibroblast cells (CHO-K1)

1995 • 18 citations

The Effect of Testicular Irradiation on Established BPH in the Dog: Evidence of a Non-Steroidal Testicular Factor for BPH Maintenance

1985 • 18 citations

Ovarian regulation of pituitary inhibin subunit and activin receptor type II gene expression: evidence for a nonsteroidal inhibitory substance.

1994 • 18 citations