Predominance of T cells that express CD45R in the CD4+ helper/inducer lymphocyte subset of neonates

The differentiation and function of human T lymphocytes

1980 • 1,548 citations

Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

1988 • 930 citations

The isolation and characterization of the human suppressor inducer T cell subset.

1985 • 860 citations

The isolation and characterization of the human helper inducer T cell subset.

1985 • 708 citations

Immunologic basis for increased susceptibility of the neonate to infection

1986 • 349 citations

Decreased Levels of Helper T Cells

1982 • 292 citations

Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsiveness.

1987 • 289 citations

Differential activation requirements for virgin and memory T cells.

1988 • 271 citations

Loss of CD45R (Lp220) represents a post-thymic T cell differentiation event.

1988 • 218 citations

The functionally distinct subpopulations of human CD4+ helper/inducer T lymphocytes defined by anti-CD45R antibodies derive sequentially from a differentiation pathway that is regulated by activation-dependent post-thymic differentiation.

1988 • 213 citations

Humoral and Cellular Immunity in Humans Studied at the Cell Level from Birth to Two Years of Age

1981 • 181 citations

Impaired production of gamma-interferon by newborn cells in vitro is due to a functionally immature macrophage.

1985 • 172 citations

Thymus-Derived Peripheral Lymphocytes from Human Newborns Inhibit Division of Their Mothers' Lymphocytes

1976 • 131 citations

Regulation of B cell differentiation by T cell subsets defined with monoclonal OKT4 and OKT8 antibodies in human cord blood.

1981 • 122 citations

B Cell Differentiation and Immunoregulatory T Cell Function in Human Cord Blood Lymphocytes

1980 • 120 citations

Reduced interferon-gamma mRNA levels in human neonates. Evidence for an intrinsic T cell deficiency independent of other genes involved in T cell activation.

1986 • 118 citations

Characterization of immature T cell subpopulations in neonatal blood

1984 • 113 citations

Induction of suppression following autologous mixed lymphocyte reaction; role of a novel 2H4 antigen

1987 • 111 citations

The subdivision of the T4 (CD4) subset on the basis of the differential expression of L-C/T200 antigens.

1987 • 110 citations

Maturation of B‐Cell Differentiation Ability and T‐Cell Regulatory Function in Infancy and Childhood

1981 • 100 citations

Development of Lymphocyte Responses and Interactions in the Human Fetus and Newborn

1981 • 100 citations

Newborn T cell suppression: early appearance, maintenance in culture, and lack of growth factor suppression.

1981 • 84 citations

Human lymphocyte differentiation antigens HB-10 and HB-11. I. Ontogeny of antigen expression.

1985 • 84 citations

Active Suppression of B Lymphocyte Maturation by Two Different Newborn T Lymphocyte Subsets

1979 • 78 citations

Lymphocyte subpopulations in the neonate: identification of an immature subset of OKT8-positive, OKT3-negative cells.

1983 • 61 citations

Delineation of suppressor and helper activity within the OKT4-defined T lymphocyte subset in human newborns.

1983 • 59 citations

The cellular basis for the induction of antigen‐specific T8 suppressor cells

1986 • 55 citations

Characterization of the human newborn response to herpesvirus antigen.

1985 • 46 citations

Immature T lymphocytes in human cord blood identified by monoclonal antibodies: A model for the study of the differentiation pathway of T cells in humans

1984 • 42 citations

Phenotypic dissection of cord blood immunoregulatory T-cell subsets by using a two-color immunofluorescence study

1986 • 40 citations

Correlation of immunoregulatory function with cell phenotype in cord blood lymphocytes.

1988 • 37 citations

Immature T lymphocytes in human neonatal blood

1985 • 30 citations

Human suppressor T cells: Induction, differentiation, and regulatory functions

1986 • 26 citations

T suppressor cell growth factor and anti-CD3 antibodies stimulate reciprocal subsets of T lymphocytes.

1987 • 23 citations

Ontogeny and postnatal persistence of a strong suppressor activity in man.

1981 • 20 citations

A mature thymocyte-like phenotypic pattern on human cord circulating T-lymphoid cells

1984 • 19 citations

T-cell subsets: effects of cryopreservation, paraformaldehyde fixation, incubation regime and choice of fluorescein-conjugated anti-mouse IgG on the percentage positive cells stained with monoclonal antibodies

1986 • 18 citations

A study of the functional capabilities of human neonatal lymphocytes for in vitro specific antibody production.

1983 • 17 citations

Defective infant antiviral cytotoxicity to herpes simplexvirus-infected cells

1983 • 15 citations

Characterization of immature T cell subpopulations in neonatal blood

1984 • 8 citations

Characterization of immature T cell subpopulations in neonatal blood [letter]

1985 • 1 citations