Specific Interaction of Oxidized Low-Density Lipoprotein With Macrophage-Derived Foam Cells Isolated From Rabbit Atherosclerotic Lesions

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Beyond Cholesterol

1989 • 6,533 citations

The Pathogenesis of Atherosclerosis — An Update

1986 • 4,951 citations

Efficient Trace-labelling of Proteins with Iodine

1958 • 2,571 citations

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The insulin signaling system.

1994 • 1,733 citations

Low density lipoprotein undergoes oxidative modification in vivo.

1989 • 1,537 citations

CD36 is a receptor for oxidized low density lipoprotein

1993 • 1,271 citations

A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

1997 • 1,210 citations

Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis.

1987 • 1,152 citations

Separation of plasma lipoproteins by density-gradient ultracentrifugation

1975 • 1,114 citations

Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils

1990 • 1,039 citations

Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.

1976 • 1,032 citations

Expression cloning of SR-BI, a CD36-related class B scavenger receptor.

1994 • 818 citations

Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins

1993 • 660 citations

The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively‐charged LDL by macrophages

1980 • 543 citations

CD36 directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes

1989 • 474 citations

Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II

1990 • 460 citations

The metabolism of very low density lipoprotein proteins. II. Studies on the transfer of apoproteins between plasma lipoproteins.

1972 • 434 citations

The Role of Oxidized Low-Density Lipoproteins in the Pathogenesis of Atherosclerosis

1992 • 386 citations

Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein

1996 • 380 citations

Human macrophage scavenger receptors: primary structure, expression, and localization in atherosclerotic lesions.

1990 • 360 citations

Reduced uptake of oxidized low density lipoproteins in monocyte-derived macrophages from CD36-deficient subjects.

1995 • 335 citations

An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors.

1990 • 311 citations

The 94- to 97-kDa mouse macrophage membrane protein that recognizes oxidized low density lipoprotein and phosphatidylserine-rich liposomes is identical to macrosialin, the mouse homologue of human CD68.

1995 • 310 citations

Enzymatic modification of low density lipoprotein by purified lipoxygenase plus phospholipase A2 mimics cell-mediated oxidative modification

1988 • 301 citations

Different fate in vivo of oxidatively modified low density lipoprotein and acetylated low density lipoprotein in rats. Recognition by various scavenger receptors on Kupffer and endothelial liver cells

1991 • 275 citations

Native and Modified Low Density Lipoproteins Increase the Functional Expression of the Macrophage Class B Scavenger Receptor, CD36

1997 • 266 citations

Interferon-gamma inhibits scavenger receptor expression and foam cell formation in human monocyte-derived macrophages.

1992 • 264 citations

Oxidized LDL Binds to CD36 on Human Monocyte-Derived Macrophages and Transfected Cell Lines

1995 • 261 citations

Regulated expression of CD36 during monocyte-to-macrophage differentiation: potential role of CD36 in foam cell formation

1996 • 260 citations

Macrophage-derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of low-density lipoproteins, and contain oxidation-specific lipid-protein adducts.

1991 • 219 citations

Macrosialin, a mouse macrophage-restricted glycoprotein, is a member of the lamp/lgp family

1993 • 214 citations

Regulation of smooth muscle cell scavenger receptor expression in vivo by atherogenic diets and in vitro by cytokines.

1995 • 176 citations

Regulation of Monocyte CD36 and Thrombospondin-1 Expression by Soluble Mediators

1996 • 166 citations

Expression of LDL Receptor, VLDL Receptor, LDL Receptor–Related Protein, and Scavenger Receptor in Rabbit Atherosclerotic Lesions

1998 • 156 citations

A macrophage receptor for oxidized low density lipoprotein distinct from the receptor for acetyl low density lipoprotein: partial purification and role in recognition of oxidatively damaged cells.

1995 • 144 citations

Rabbit aortic smooth muscle cells express inducible macrophage scavenger receptor messenger RNA that is absent from endothelial cells.

1992 • 125 citations

The role of macrophages in atherogenesis

1993 • 121 citations

Expression of the Macrophage Scavenger Receptor in Atheroma

1995 • 106 citations

Rat liver Kupffer and endothelial cells express different binding proteins for modified low density lipoproteins. Kupffer cells express a 95-kDa membrane protein as a specific binding site for oxidized low density lipoproteins.

1994 • 70 citations

Synthesis, Processing, and Intracellular Transport of CD36 during Monocytic Differentiation

1996 • 70 citations

Oxidized LDL Induces Enhanced Antibody Formation and MHC Class II–Dependent IFN-γ Production in Lymphocytes From Healthy Individuals

1995 • 66 citations

Characterization of a receptor for oxidized low-density lipoproteins on rat Kupffer cells: similarity to macrosialin

1997 • 54 citations

Decrease in Scavenger Receptor Expression in Human Monocyte–Derived Macrophages Treated With Granulocyte Macrophage Colony-Stimulating Factor

1996 • 38 citations

Detection and localization of tumor necrosis factor-α in WHHL rabbit arteries

1996 • 33 citations