In vitro differentiation of murine embryonic stem cells toward a renal lineage

Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4

1998 • 3,360 citations

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

1985 • 1,983 citations

Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome

1998 • 1,822 citations

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.

1995 • 1,782 citations

Embryonic Stem Cells Express Neuronal Properties in Vitro

1995 • 1,173 citations

Derivation of Oocytes from Mouse Embryonic Stem Cells

2003 • 1,073 citations

Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4

1994 • 1,056 citations

Cloning and expression of apical membrane water channel of rat kidney collecting tubule

1993 • 1,002 citations

Hematopoietic commitment during embryonic stem cell differentiation in culture.

1993 • 919 citations

Expression pattern of the mouse T gene and its role in mesoderm formation

1990 • 854 citations

Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite

1998 • 838 citations

Development of definitive endoderm from embryonic stem cells in culture

2004 • 824 citations

Nephrin is specifically located at the slit diaphragm of glomerular podocytes

1999 • 736 citations

The Evolving Diabetes Burden in the United States

2004 • 678 citations

Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules.

1988 • 669 citations

The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo

1993 • 582 citations

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.

1994 • 574 citations

Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system

1990 • 562 citations

CHIP28 water channels are localized in constitutively water-permeable segments of the nephron.

1993 • 543 citations

The organizer factors Chordin and Noggin are required for mouse forebrain development

2000 • 528 citations

Divergence and convergence of TGF‐β/BMP signaling

2001 • 503 citations

Tracking mesoderm induction and its specification to the hemangioblast during embryonic stem cell differentiation

2003 • 502 citations

Spontaneous differentiation of germ cells from human embryonic stem cells in vitro

2004 • 486 citations

Evidence for Involvement of Activin A and Bone Morphogenetic Protein 4 in Mammalian Mesoderm and Hematopoietic Development

1995 • 464 citations

Generation of purified neural precursors from embryonic stem cells by lineage selection

1998 • 463 citations

In vitro differentiation of embryonic stem cells into glial cells and functional neurons

1995 • 426 citations

Differentiation of pluripotent embryonic stem cells into the neuronal lineage in vitro gives rise to mature inhibitory and excitatory neurons

1995 • 361 citations

Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems

2002 • 345 citations

Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus

1997 • 332 citations

Nephrin localizes to the slit pore of the glomerular epithelial cell

1999 • 316 citations

Teratoma Formation Leads to Failure of Treatment for Type I Diabetes Using Embryonic Stem Cell-Derived Insulin-Producing Cells

2005 • 313 citations

Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips

1996 • 312 citations

GDNF/Ret signaling and the development of the kidney

2006 • 306 citations

Characterization of a pluripotent stem cell line derived from a mouse embryo

1984 • 302 citations

Nephrogenic Factors Promote Differentiation of Mouse Embryonic Stem Cells into Renal Epithelia

2005 • 261 citations

The Role of GDNF/Ret Signaling in Ureteric Bud Cell Fate and Branching Morphogenesis

2005 • 251 citations

A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells

2004 • 242 citations

[49] Derivation of embryonic stem cell lines

1993 • 228 citations

Testicular Cell Conditioned Medium Supports Differentiation of Embryonic Stem Cells into Ovarian Structures Containing Oocytes

2005 • 219 citations

Localization of the thiazide sensitive Na-Cl cotransporter, rTSC1, in the rat kidney

1996 • 185 citations

WT1 regulates the expression of the major glomerular podocyte membrane protein Podocalyxin

2001 • 176 citations

Pod-1, a mesoderm-specific basic-helix-loop-helix protein expressed in mesenchymal and glomerular epithelial cells in the developing kidney

1998 • 160 citations

Bone morphogenetic protein-4 (BMP-4) acts during gastrula stages to cause ventralization of Xenopus embryos

1996 • 143 citations

BMP-2 and OP-1 exert direct and opposite effects on renal branching morphogenesis

1997 • 138 citations

The primitive streak geneMixl1is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells

2005 • 135 citations

Efficient Cardiomyogenic Differentiation of Embryonic Stem Cell by Fibroblast Growth Factor 2 and Bone Morphogenetic Protein 2

2004 • 135 citations

BMP-4 affects the differentiation of metanephric mesenchyme and reveals an early anterior-posterior axis of the embryonic kidney

2000 • 132 citations

An in vitro globin gene switching model based on differentiated embryonic stem cells.

1990 • 125 citations

Architectural patterns in branching morphogenesis in the kidney

1998 • 117 citations

Wnt4-transformed mouse embryonic stem cells differentiate into renal tubular cells

2005 • 114 citations

Identification of Podocalyxin-like Protein 1 as a Novel Cell Surface Marker for Hemangioblasts in the Murine Aorta-Gonad-Mesonephros Region

1999 • 113 citations

A Minimal Ksp-Cadherin Promoter Linked to a Green Fluorescent Protein Reporter Gene Exhibits Tissue-Specific Expression in the Developing Kidney and Genitourinary Tract

2002 • 112 citations

BMP-4 inhibits neural differentiation of murine embryonic stem cells

1999 • 111 citations

Health‐related quality of life among haemodialysis patients – relationship with clinical indicators, morbidity and mortality

2006 • 110 citations

Integration of Embryonic Stem Cells in Metanephric Kidney Organ Culture

2005 • 108 citations

Distribution of mineralocorticoid and glucocorticoid receptor mRNA along the nephron

1993 • 108 citations

The activation and maintenance ofPax2expression at the mid-hindbrain boundary is controlled by separate enhancers

2002 • 104 citations

Immunolocalization of Renal Mineralocorticoid Receptors with an Antiserum against a Peptide Deduced from the Complementary Deoxyribonucleic Acid Sequence

1989 • 100 citations

Nephron endowment in glial cell line-derived neurotrophic factor (GDNF) heterozygous mice

2001 • 92 citations

In vitro induction of the pronephric duct in Xenopus explants

2002 • 92 citations

Noggin and Chordin Have Distinct Activities in Promoting Lineage Commitment of Mouse Embryonic Stem (ES) Cells

2002 • 88 citations

Neural differentiation of mouse embryonic stem cells in chemically defined medium

2005 • 82 citations

Pattern of olfactory bulb innervation returns after recovery from reversible peripheral deafferentation

2000 • 79 citations

Teratoma formation and hepatocyte differentiation in mouse liver transplanted with mouse embryonic stem cell–derived embryoid bodies

2005 • 52 citations

Cells differentiated from mouse embryonic stem cells via embryoid bodies express renal marker molecules

2006 • 47 citations

Exogenous BMP-4 amplifies asymmetric ureteric branching in the developing mouse kidney in vitro

2005 • 41 citations

Strategies to increase living donor kidney transplants

2005 • 15 citations

Enrichment of blood from embryonic stem cells in vitro

1998 • 10 citations