Superantigen Recognition by γδ T Cells

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Identification of common molecular subsequences

1981 • 9,753 citations

[26] Raster3D: Photorealistic molecular graphics

1997 • 3,784 citations

Raster3D Version 2.0. A program for photorealistic molecular graphics

1994 • 2,515 citations

The Staphylococcal Enterotoxins and Their Relatives

1990 • 1,914 citations

Natural and synthetic non-peptide antigens recognized by human γδ T cells

1995 • 974 citations

Stimulation of Human γδ T Cells by Nonpeptidic Mycobacterial Ligands

1994 • 685 citations

Modulation of Epithelial Cell Growth by Intraepithelial γδ T Cells

1994 • 644 citations

Stimulation of γδ T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma

2000 • 630 citations

Specificity and function of T cells bearing γδ receptors

1988 • 570 citations

Evidence for extrathymic changes in the T cell receptor gamma/delta repertoire.

1990 • 510 citations

Stimulation of a major subset of lymphocytes expressing T cell receptor γδ by an antigen derived from mycobacterium tuberculosis

1989 • 491 citations

Direct presentation of nonpeptide prenyl pyrophosphate antigens to human γδ T cells

1995 • 468 citations

Nonpeptide ligands for human gamma delta T cells.

1994 • 373 citations

Human γδ T Cells Recognize Alkylamines Derived from Microbes, Edible Plants, and Tea

1999 • 368 citations

Self-Recognition of Cd1 by γ/δ T Cells

2000 • 367 citations

A large fraction of human peripheral blood gamma/delta + T cells is activated by Mycobacterium tuberculosis but not by its 65-kD heat shock protein.

1990 • 331 citations

α, β, γ, and δ T Cell Antigen Receptor Genes Arose Early in Vertebrate Phylogeny

1997 • 285 citations

Crystal structure of a T-cell receptor β-chain complexed with a superantigen

1996 • 285 citations

V gamma 2V delta 2 TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer.

1995 • 276 citations

HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells.

1990 • 253 citations

Superantigens: Bacterial and Viral Proteins that Manipulate the Immune System

1993 • 236 citations

Protective role of γ/δ T cells and α/β T cells in tuberculosis

1995 • 219 citations

Mutations defining functional regions of the superantigen staphylococcal enterotoxin B.

1992 • 208 citations

Selection by two powerful antigens may account for the presence of the major population of human peripheral gamma/delta T cells.

1991 • 201 citations

Crystal structure of the superantigen staphylococcal enterotoxin type A.

1995 • 201 citations

Three-Dimensional Structure of the Complex between a T Cell Receptor β Chain and the Superantigen Staphylococcal Enterotoxin B

1998 • 193 citations

Biology of the Human γ T‐Cell Receptor

1991 • 185 citations

X-ray Structures of the Antigen-binding Domains from Three Variants of Humanized anti-p185HER2 Antibody 4D5 and Comparison with Molecular Modeling

1993 • 185 citations

Early activation of human V gamma 9V delta 2 T cell broad cytotoxicity and TNF production by nonpeptidic mycobacterial ligands.

1995 • 177 citations

Specific recognition of staphylococcal enterotoxin A by human T cells bearing receptors with the Vγ9 region

1990 • 175 citations

Frontiers of the immune system

1988 • 174 citations

Staphylococcal enterotoxin A has two cooperative binding sites on major histocompatibility complex class II.

1995 • 174 citations

Antigen recognition by human γδ T cells: pattern recognition by the adaptive immune system

2000 • 165 citations

Increased γδ T cells in acute Plasmodium falciparum malaria

1990 • 163 citations

CD94/NKG2 inhibitory receptor complex modulates both anti-viral and anti-tumoral responses of polyclonal phosphoantigen-reactive V gamma 9V delta 2 T lymphocytes.

1997 • 156 citations

Predominant activation and expansion of V gamma 9-bearing gamma delta T cells in vivo as well as in vitro in Salmonella infection.

1992 • 154 citations

Control of self‐reactive cytotoxic T lymphocytes expressing γδ T cell receptors by natural killer inhibitory receptors

1997 • 151 citations

Therapeutic potentiation of the immune system by costimulatory Schiff-base-forming drugs

1995 • 151 citations

An innate view of γδ T cells

1997 • 142 citations

Close correlation between Daudi and mycobacterial antigen recognition by human gamma delta T cells and expression of V9JPC1 gamma/V2DJC delta-encoded T cell receptors.

1993 • 131 citations

TCR usage and functional capabilities of human gamma delta T cells at birth.

1994 • 128 citations

Stimulation of γδ T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma

2000 • 126 citations

Lymphocytes bearing the γδ T cell receptor in acute Brucella melitensis infection

1993 • 125 citations

Superantigen binding to a T cell receptor beta chain of known three-dimensional structure.

1995 • 124 citations

Crucial role of TCR gamma chain junctional region in prenyl pyrophosphate antigen recognition by gamma delta T cells.

1998 • 122 citations

Two adjacent residues in staphylococcal enterotoxins A and E determine T cell receptor V beta specificity.

1993 • 122 citations

Increased frequency of gamma delta T cells in cerebrospinal fluid and peripheral blood of patients with multiple sclerosis. Reactivity, cytotoxicity, and T cell receptor V gene rearrangements.

1995 • 117 citations

Transient increase in circulating gamma/delta T cells during Plasmodium vivax malarial paroxysms.

1994 • 114 citations

A predominance of the T cell receptor V gamma 2/V delta 2 subset in human mycobacteria-responsive T cells suggests germline gene encoded recognition.

1991 • 113 citations

Multiple binding sites for bacterial superantigens on soluble class II MHC molecules

1995 • 112 citations

Functionally distinct subsets of human γ/δ T cells

1991 • 110 citations

Crucial Role of TCRγ Chain Junctional Region in Prenyl Pyrophosphate Antigen Recognition by γδ T Cells

1998 • 107 citations

T-Lymphocytes with γδ + Vδ2+ Antigen Receptors Are Present in Increased Proportions in a Fraction of Patients with Tuberculosis or with Sarcoidosis

1993 • 105 citations

Direct Ex Vivo Analysis of Activated, Fas-sensitive Autoreactive T Cells in Human Autoimmune Disease

1997 • 104 citations

Lymphocytes bearing the gamma delta T-cell receptor in acute toxoplasmosis.

1992 • 98 citations

Major Histocompatibility Complex Class I Molecules Modulate Activation Threshold and Early Signaling of T Cell Antigen Receptor–γ/δ Stimulated by Nonpeptidic Ligands

1997 • 87 citations

Staphylococcal toxins bind to different sites on HLA-DR.

1991 • 86 citations

A lectin-binding, protease-resistant mycobacterial ligand specifically activates V gamma 9+ human gamma delta T cells.

1992 • 77 citations

Further analysis of the T cell receptor gamma/delta+ peripheral lymphocyte subset. The V delta 1 gene segment is expressed with either C alpha or C delta.

1990 • 74 citations

Predominant expansion of V gamma 9/V delta 2 T cells in a tularemia patient

1992 • 74 citations

Localization of a site on bacterial superantigens that determines T cell receptor beta chain specificity.

1993 • 73 citations

Increase of gamma/delta T cells in hospital workers who are in close contact with tuberculosis patients

1994 • 72 citations

Antigen recognition by MHC-incompatible cells of a human mismatched chimera.

1988 • 71 citations

T-cell receptor δ-chain can substitute for α to form a βδ heterodimer

1989 • 68 citations

Staphylococcal enterotoxin D functions as a human B cell superantigen by rescuing VH4-expressing B cells from apoptosis.

1996 • 64 citations

Lymphocytosis ofγ/δT Cells in Human Ehrlichiosis

1995 • 63 citations

Residues defining Vβ specificity in staphylococcal enterotoxins

1995 • 63 citations

Virus-encoded superantigens

1996 • 55 citations

Functional and phenotypic differences between CD4+ and CD4- T cell receptor-gamma delta clones from peripheral blood.

1991 • 54 citations

Covalent chemical events in immune induction: fundamental and therapeutic aspects

1996 • 53 citations

Evidence for an intercellular covalent reaction essential in antigen-specific T cell activation.

1989 • 52 citations

Isolation of HLA-DR1.(staphylococcal enterotoxin A)2 trimers in solution.

1995 • 48 citations

Structure‐function studies of T‐cell receptor‐superantigen interactions

1998 • 48 citations

Different Percentages of Peripheral Blood γδ⁺ T Cells in Healthy Individuals from Different Areas of the World

1996 • 40 citations

Direct presentation of non-peptide prenyl pyrophosphate antigens to human γδ T cells

1996 • 38 citations

MHC-specific recognition of a bacterial superantigen by weakly reactive T cells.

1994 • 22 citations

Gene transfer studies of T cell receptor-gamma delta recognition. Specificity for staphylococcal enterotoxin A is conveyed by V gamma 9 alone.

1994 • 21 citations

Superantigen Reactivity of γδ T Cell Clones Isolated from Patients with Multiple Sclerosis and Controls

1995 • 15 citations

Reactivity of Human γδ T Cells to Staphylococcal Enterotoxins: a Restricted Reaction Pattern mediated by Two Distinct Recognition Pathways

1993 • 13 citations

A natural mutation of the amino acid residue at position 60 destroys staphylococcal enterotoxin A murine T-cell mitogenicity

1995 • 13 citations

Immune responsiveness in mutant mice lacking T-cell receptor alpha beta+ cells.

1995 • 12 citations

Bacterial Superantigens Induce The Proliferation of Resting γ/δ Receptor Bearing T Cells

1995 • 11 citations

Residues near the amino and carboxyl termini of staphylococcal enterotoxin E independently mediate TCR V beta-specific interactions.

1996 • 10 citations

Relative Ability of Distinct Isotypes of Human Major Histocompatibility Complex Class II Molecules in Binding Staphylococcal Enterotoxin A

1991 • 6 citations

Immobilized Staphylococcal Enterotoxin A Is Sufficient to Induce T Cell Proliferation

1993 • 5 citations

Deleted Work

1955 • 0 citations