Mechanism of Ubiquitin Conjugating Enzyme E2-230K: Catalysis Involving a Thiol Relay?

The ubiquitin-proteasome proteolytic pathway

1994 • 1,778 citations

Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown.

1983 • 1,105 citations

Protein ubiquitination involving an E1–E2–E3 enzyme ubiquitin thioester cascade

1995 • 960 citations

A 26 S protease subunit that binds ubiquitin conjugates.

1994 • 759 citations

Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85

1984 • 533 citations

Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway.

1995 • 213 citations

The ‘second-codon rule’ and autophosphorylation govern the stability and activity of Mos during the meiotic cell cycle in Xenopus oocytes.

1992 • 147 citations

Substrate properties of site-specific mutant ubiquitin protein (G76A) reveal unexpected mechanistic features of ubiquitin-activating enzyme (E1).

1994 • 88 citations

Affinity purification of ubiquitin-protein ligase on immobilized protein substrates. Evidence for the existence of separate NH2-terminal binding sites on a single enzyme.

1990 • 73 citations

Binding Sites of Ubiquitin-Protein Ligase

1989 • 70 citations

Human plasma lecithin-cholesterol acyltransferase. The vicinal nature of cysteine 31 and cysteine 184 in the catalytic site.

1988 • 68 citations

The oxidation of dithiols

1947 • 61 citations

Inhibition of ubiquitin-protein ligase (E3) by mono- and bifunctional phenylarsenoxides. Evidence for essential vicinal thiols and a proximal nucleophile.

1992 • 40 citations

Iodination of tyrosine 59 of ubiquitin selectively blocks ubiquitin's acceptor activity in diubiquitin synthesis catalyzed by E2(25K).

1992 • 39 citations

Dynamics of Ubiquitin Conjugation during Erythroid Differentiation in Vitro

1995 • 28 citations

Ubiquitin activating enzyme

1984 • 5 citations