Molecular Basis for Bacterial Class I Release Factor Methylation by PrmC

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

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Molecular cloning: A laboratory manual

1990 • 85,659 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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Solvent content of protein crystals

1968 • 7,954 citations

MOLREP: an Automated Program for Molecular Replacement

1997 • 4,644 citations

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

1993 • 3,564 citations

ESPript: analysis of multiple sequence alignments in PostScript.

1999 • 2,820 citations

Satisfying Hydrogen Bonding Potential in Proteins

1994 • 2,076 citations

The atomic structure of protein-protein recognition sites 1 1Edited by A. R. Fersht

1999 • 1,932 citations

The Crystal Structure of Human Eukaryotic Release Factor eRF1—Mechanism of Stop Codon Recognition and Peptidyl-tRNA Hydrolysis

2000 • 456 citations

Mutations in the highly conserved GGQ motif of class 1 polypeptide release factors abolish ability of human eRF1 to trigger peptidyl-tRNA hydrolysis

1999 • 352 citations

A tripeptide ‘anticodon’ deciphers stop codons in messenger RNA

2000 • 285 citations

Release factor RF3 in E.coli accelerates the dissociation of release factors RF1 and RF2 from the ribosome in a GTP-dependent manner

1997 • 281 citations

Mutations in a new chromosomal gene of Escherichia coli K-12, pcnB, reduce plasmid copy number of pBR322 and its derivatives

1986 • 263 citations

A cryo-electron microscopic study of ribosome-bound termination factor RF2

2003 • 235 citations

Translational termination comes of age

2000 • 202 citations

Bacterial Polypeptide Release Factor RF2 Is Structurally Distinct from Eukaryotic eRF1

2001 • 200 citations

Structure of the Escherichia coli ribosomal termination complex with release factor 2

2003 • 199 citations

Protein methylation

1993 • 183 citations

The hemK gene in Escherichia coli encodes the N5-glutamine methyltransferase that modifies peptide release factors

2002 • 150 citations

A post-translational modification in the GGQ motif of RF2 from Escherichia coli stimulates termination of translation

2000 • 142 citations

A temperature-sensitive mutant of Escherichia coli that shows enhanced misreading of UAG/A and increased efficiency for tRNA nonsense suppressors

1984 • 129 citations

HemK, a class of protein methyl transferase with similarity to DNA methyl transferases, methylates polypeptide chain release factors, and hemK knockout induces defects in translational termination

2002 • 117 citations

The SAXS Solution Structure of RF1 Differs from Its Crystal Structure and Is Similar to Its Ribosome Bound Cryo-EM Structure

2005 • 100 citations

The Glutamine Residue of the Conserved GGQ Motif in Saccharomyces cerevisiae Release Factor eRF1 Is Methylated by the Product of the YDR140w Gene

2004 • 92 citations

Structural Analyses of Peptide Release Factor 1 from Thermotoga maritima Reveal Domain Flexibility Required for Its Interaction with the Ribosome

2004 • 88 citations

Functional Roles of Conserved Amino Acid Residues in DNA Methyltransferases Investigated by Site-directed Mutagenesis of theEcoRV Adenine-N6-methyltransferase

1998 • 63 citations

Shutdown in protein synthesis due to the expression of mini-genes in bacteria

1999 • 58 citations

A direct estimation of the context effect on the efficiency of termination

1998 • 58 citations

Structures along the Catalytic Pathway of PrmC/HemK, an N⁵-Glutamine AdoMet-Dependent Methyltransferase

2003 • 55 citations

Mapping and complementation studies of the gene for release factor 1

1986 • 52 citations

Cloning and sequencing of a previously unidentified gene that is involved in the biosynthesis of heme in Escherichia coli

1995 • 49 citations

Stop codon recognition and interactions with peptide release factor RF3 of truncated and chimeric RF1 and RF2 from Escherichia coli

2003 • 48 citations

Genetics of ribosomal protein methylation in Escherichia coli

1977 • 40 citations

Structural Characterization and Comparative Phylogenetic Analysis of Escherichia coli HemK, a Protein (N5)-glutamine Methyltransferase

2004 • 39 citations

Class-1 polypeptide chain release factors are structurally and functionally similar to suppressor tRNAs and comprise different structural-functional families of prokaryotic/mitochondrial and eukaryotic/archaebacterial factors

2000 • 24 citations

Molecular Morphology of Eukaryotic Class-1 Translation Termination Factor eRF1 in Solution

2004 • 19 citations