Adaptive changes in the responsiveness of adenylate cyclase to catecholamines

The Pineal Gland: A Neurochemical Transducer

1974 • 872 citations

Action of various antidepressant treatments reduces reactivity of noradrenergic cyclic AMP-generating system in limbic forebrain

1975 • 599 citations

Presynaptic modulation of beta adrenergic receptors in rat cerebral cortex after treatment with antidepressants.

1978 • 440 citations

Mechanisms of supersensitivity and subsensitivity to sympathomimetic amines.

1966 • 359 citations

Cyclic Nucleotides in the Nervous System

1977 • 297 citations

Subsensitivity of adenylate cyclase and decreased beta-adrenergic receptor binding after chronic exposure to (minus)-isoproterenol in vitro.

1975 • 235 citations

Agonist-specific refractoriness induced by isoproterenol. Studies with mutant cells.

1976 • 219 citations

Stimulation and Desensitization of Macrophage Adenylate Cyclase by Prostaglandins and Catecholamines

1974 • 166 citations

Self regulation of membrane receptors

1976 • 144 citations

Role of beta-adrenergic receptors in catecholamine-induced desensitization of adenylate cyclase in human astrocytoma cells.

1978 • 130 citations

Psychoactive drug effects on a system which generates cyclic AMP in brain

1976 • 124 citations

Effects of neurohumoral and adrenergic agents on cyclic amp levels in various areas of the rat brain in vitro

1973 • 112 citations

PHYSIOLOGICAL EFFECTS OF DENERVATION OF MUSCLE*

1974 • 112 citations

Reversal of Catecholamine Refractoriness by Inhibitors of RNA and Protein Synthesis

1974 • 111 citations

Increased cyclic AMP response to norepinephrine in the rat brain following 6-hydroxydopamine

1972 • 99 citations

Regulation of Phosphodiesterase Synthesis: Requirement for Cyclic Adenosine Monophosphate-Dependent Protein Kinase

1973 • 93 citations

The effect of tri-iodothyronine in combination with imipramine on [3H]-cyclic AMP production in slices of rat cerebral cortex

1974 • 92 citations

Effects of 6-hydroxydopamine on the development of the beta adrenergic receptor/adenylate cyclase system in rat cerebral cortex.

1977 • 86 citations

Hormone-induced Desensitisation of Hormonal Control of Cyclic AMP Levels in Human Diploid Fibroblasts

1973 • 72 citations

Norepinephrine-Sensitive Systems Generating Adenosine 3',5'-Monophosphate: Increased Responses in Cerebral Cortical Slices from Reserpine-Treated Rats

1974 • 56 citations

Increased response to catecholamines of the cyclic AMP system of rat pineal gland induced by decreased sympathetic activity

1974 • 47 citations

Correlation between brain adenyl cyclase activity and spontaneous motor activity in rats after chronic reserpine treatment

1974 • 40 citations

Subsensitivity of noradrenaline-stimulated cyclic AMP accumulation in brain slices of d-amphetamine-treated mice

1975 • 34 citations

Altered responsiveness of adenosine 3′,5′-monophosphate-generating systems in rat cortical slices after lesions of the medial forebrain bundle

1975 • 32 citations

Altered responsiveness of adenosine 3′,5′-monophosphate-generating systems in brain slices from adult rats after neonatal treatment with 6-hydroxydopamine

1975 • 18 citations