The Oxygen and Carbon Monoxide Reactions of Heme Oxygenase

Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications

1988 • 1,699 citations

Microsomal Heme Oxygenase

1969 • 1,348 citations

Mechanisms of Ligand Recognition in Myoglobin

1994 • 746 citations

The effects of amino acid substitution at position E7 (residue 64) on the kinetics of ligand binding to sperm whale myoglobin.

1990 • 288 citations

Purification and properties of heme oxygenase from pig spleen microsomes.

1978 • 189 citations

Analysis of the kinetic barriers for ligand binding to sperm whale myoglobin using site-directed mutagenesis and laser photolysis techniques.

1990 • 183 citations

Features of the reaction of heme degradation catalyzed by the reconstituted microsomal heme oxygenase system.

1978 • 163 citations

Characterization of recombinant soybean leghemoglobin a and apolar distal histidine mutants

1997 • 138 citations

Oxygenated form of heme . heme oxygenase complex and requirement for second electron to initiate heme degradation from the oxygenated complex.

1980 • 127 citations

Purification and properties of heme oxygenase from rat liver microsomes.

1979 • 112 citations

Heme-heme oxygenase complex. Structure of the catalytic site and its implication for oxygen activation.

1994 • 110 citations

Identification of Histidine 25 as the Heme Ligand in Human Liver Heme Oxygenase

1994 • 102 citations

Oxygen and One Reducing Equivalent Are Both Required for the Conversion of α-Hydroxyhemin to Verdoheme in Heme Oxygenase

1996 • 101 citations

Oxygen-Bound Heme-Heme Oxygenase Complex: Evidence for a Highly Bent Structure of the Coordinated Oxygen

1995 • 87 citations

Heme Oxygenase-2

1995 • 85 citations

Heme-Heme Oxygenase Complex: Structure and Properties of the Catalytic Site from Resonance Raman Scattering

1994 • 82 citations

Functional effects of heme orientational disorder in sperm whale myoglobin.

1987 • 80 citations

Structural characterization of verdoheme analogs. Iron complexes of octaethyloxoporphyrin

1993 • 74 citations

The step of carbon monoxide liberation in the sequence of heme degradation catalyzed by the reconstituted microsomal heme oxygenase system.

1982 • 72 citations

Demonstration That Histidine-25, But Not Histidine-132, Is the Axial Heme Ligand in Rat Heme Oxygenase-1

1995 • 59 citations

Kinetic and equilibrium studies of the reactions of heme-substituted horse heart myoglobins with oxygen and carbon monoxide.

1976 • 49 citations

Proton NMR Investigation of Substrate-Bound Heme Oxygenase: Evidence for Electronic and Steric Contributions to Stereoselective Heme Cleavage

1994 • 46 citations

Histidine-132 Does Not Stabilize a Distal Water Ligand and Is Not an Important Residue for the Enzyme Activity in Heme Oxygenase-1

1997 • 45 citations

Resonance Raman Spectroscopic Characterization of α-Hydroxyheme and Verdoheme Complexes of Heme Oxygenase

1997 • 39 citations

A New Intermediate of Heme Degradation Catalyzed by the Heme Oxygenase System1

1980 • 34 citations

Heme degradation by the microsomal heme oxygenase system

1980 • 26 citations

Photo-Reversal by Monochromatic Light of the Carbon Monoxide-Inhibited Heme Degradation Catalyzed by the Reconstituted Heme Oxygenase System1

1981 • 7 citations