The Promoter of the Human Type I 5′‐Deiodinase Gene — Mapping of the Transcription Start Site and Identification of a DR+4 Thyroid‐Hormone‐Responsive Element

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

1991 • 1,725 citations

Thyroid Hormone Receptors: Multiple Forms, Multiple Possibilities*

1993 • 1,009 citations

Differential Recognition of Target Genes by Nuclear Receptor Monomers, Dimers, and Heterodimers*

1994 • 789 citations

Depletion of L-3,5,3'-Triiodothyronine and L-Thyroxine in Euthyroid Calf Serum for Use in Cell Culture Studies of the Action of Thyroid Hormone*

1979 • 653 citations

Identification of type I iodothyronine 5′-deiodinase as a selenoenzyme

1990 • 407 citations

Oligodeoxyribonucleotide ligation to single-stranded cDNAs: a new tool for cloning 5′ ends of mRNAs and for constructing cDNA libraries byin vitroamplification

1991 • 312 citations

A pituitary-specific trans-acting factor can stimulate transcription from the growth hormone promoter in extracts of nonexpressing cells

1987 • 301 citations

Tissue-specific regulation of selenoenzyme gene expression during selenium deficiency in rats

1995 • 290 citations

Euthyroid Sick Syndrome: An Overview

1997 • 259 citations

Widely Spaced, Directly Repeated PuGGTCA Elements Act as Promiscuous Enhancers for Different Classes of Nuclear Receptors

1995 • 167 citations

A Novel Retinoid X Receptor-Independent Thyroid Hormone Response Element Is Present in the Human Type 1 Deiodinase Gene

1995 • 145 citations

The thyroid gland is a major source of circulating T3 in the rat.

1993 • 137 citations

Retinoids stimulate type I iodothyronine 5'-deiodinase activity in human follicular thyroid carcinoma cell lines.

1994 • 118 citations

A Family of POU-Domain and Pit-1 Tissue-Specific Transcription Factors in Pituitary and Neuroendocrine Development

1990 • 115 citations

Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase.

1992 • 111 citations

The Role of Selenium in Thyroid Hormone Action*

1992 • 108 citations

Thyroid hormone deiodinases--a selenoenzyme family acting as gate keepers to thyroid hormone action.

1996 • 93 citations

The role of cytokines in the lipopolysaccharide-induced sick euthyroid syndrome in mice

1995 • 88 citations

Differential selenium-dependent expression of type I 5′-deiodinase and glutathione peroxidase in the porcine epithelial kidney cell line LLC-PK1

1995 • 82 citations

Structural and functional differences in the dio1 gene in mice with inherited type 1 deiodinase deficiency.

1995 • 77 citations

Continuous growth of proximal tubular kidney epithelial cells in hormone-supplemented serum-free medium.

1982 • 70 citations

Characterization of a functional promoter for the human retinoic acid receptor-alpha (hRAR-α)

1990 • 70 citations

Activation of the transcription factor NF-kappa B in human tracheobronchial epithelial cells by inflammatory stimuli

1995 • 55 citations

Cytokines modulate type I iodothyronine deiodinase mRNA levels and enzyme activity in FRTL-5 rat thyroid cells

1994 • 53 citations

Retinoids stimulate type I iodothyronine 5'-deiodinase activity in human follicular thyroid carcinoma cell lines

1994 • 51 citations

Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase

1992 • 50 citations

Rapid stimulation of type I 5′-deiodinase in rat pituitaries by 3,3′,5-triiodo-l-thyronine

1995 • 44 citations

Structure of the Human Type I Iodothyronine 5′-Deiodinase Gene and Localization to Chromosome 1p32–p33

1997 • 41 citations

Promoter independent down-regulation of the firefly luciferase gene by T3 and T3 receptor in CV1 cells

1993 • 37 citations

Structural and functional differences in the dio1 gene in mice with inherited type 1 deiodinase deficiency

1995 • 34 citations

Thyrotropin (TSH) action on thyroid hormone deiodination and secretion: one aspect of thyrotropin regulation of thyroid cell biology.

1990 • 32 citations

Thyrotropin and triiodothyronine regulate iodothyronine 5'-deiodinase messenger ribonucleic acid levels in FRTL-5 rat thyroid cells.

1992 • 30 citations

Is There a Negative TRE in the Luciferase Reporter cDNA?

1996 • 28 citations

Identification ofCis-Acting Promoter Elements Important for Expression of the Mouse Glycoprotein Hormone α-Subunit Gene in Thyrotropes

1990 • 26 citations

Thyrotropin and triiodothyronine regulate iodothyronine 5'-deiodinase messenger ribonucleic acid levels in FRTL-5 rat thyroid cells

1992 • 23 citations

Activation of the transcription factor NF-KB in GH3 pituitary cells

1994 • 23 citations

Effects of ritanserin, a novel serotonin-s2 receptor antagonist, on the secretion of pituitary hormones in normal humans

1994 • 14 citations

The structure of the coding and 5'-flanking region of the type 1 iodothyronine deiodinase (dio1) gene is normal in a patient with suspected congenital dio1 deficiency.

1996 • 11 citations

The structure of the coding and 5'-flanking region of the type 1 iodothyronine deiodinase (dio1) gene is normal in a patient with suspected congenital dio1 deficiency

1996 • 3 citations