T-cell regulation of macrophage function
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Abstract
References (42)
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IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells.
1991 • 1,880 citations
Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.
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Cloning of a T Cell Growth Factor that Interacts with the β Chain of the Interleukin-2 Receptor
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1991 • 1,253 citations
The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor.
1994 • 990 citations
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1994 • 888 citations
IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression.
1993 • 862 citations
Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.
1993 • 792 citations
The role of IL-10 in crossregulation of TH1 and TH2 responses
1991 • 775 citations
IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages.
1992 • 709 citations
Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10.
1993 • 657 citations
Direct effects of IL-10 on subsets of human CD4+ T cell clones and resting T cells. Specific inhibition of IL-2 production and proliferation.
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Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation.
1993 • 569 citations
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1993 • 393 citations
B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation.
1994 • 367 citations
Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells.
1994 • 367 citations
Interleukin‐13 alters the activation state of murine macrophages in vitro: Comparison with interleukin‐4 and interferon‐γ
1994 • 298 citations
CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help.
1993 • 274 citations
Modulation of murine macrophage function by IL-13.
1993 • 251 citations
Interleukin‐12/T cell stimulating factor, a cytokine with multiple effects on T helper type 1 (Th1) but not on Th2 cells
1993 • 241 citations
Differential effects of blockade of CD28-B7 on the development of Th1 or Th2 effector cells in experimental leishmaniasis.
1994 • 234 citations
Mechanisms generating functionally heterogeneous macrophages: chaos revisited
1993 • 221 citations
CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production.
1994 • 210 citations
Immunological regulation of experimental cutaneous leishmaniasis. IV. Prophylactic effect of sublethal irradiation as a result of abrogation of suppressor T cell generation in mice genetically susceptible to leishmania tropica
1981 • 199 citations
Ligation of B7 with CD28/CTLA‐4 on T cells results in CD40 ligand expression, interleukin‐4 secretion and efficient help for antibody production by B cells
1993 • 153 citations
IL-4 treatment of small splenic B cells induces costimulatory molecules B7-1 and B7-2.
1994 • 126 citations
IL-2. A cofactor for induction of activated macrophage resistance to infection.
1990 • 78 citations
Keratinocyte-derived T cell costimulation induces preferential production of IL-2 and IL-4 but not IFN-gamma.
1994 • 75 citations
IL-10 inhibits the synthesis of migration inhibitory factor and migration inhibitory factor-mediated macrophage activation.
1993 • 71 citations
CD2/LFA-3 or LFA-l/ICAM-1 but not CD28/B7 interactions can augment cytotoxicity by virus-specific CD8+ cytotoxic T lymphocytes
1993 • 61 citations
Role of IL-6, IL-1, and CD28 signaling in responses of mouse CD4+ T cells to immobilized anti-TCR monoclonal antibody.
1994 • 39 citations
Monocytes provide a novel costimulatory signal to T cells that is not mediated by the CD28/B7 interaction.
1994 • 32 citations
Mechanistic differences between migration inhibitory factor (MIF) and IFN-gamma for macrophage activation. MIF and IFN-gamma synergize with lipid A to mediate migration inhibition but only IFN-gamma induces production of TNF-alpha and nitric oxide.
1993 • 30 citations
Ligation of CD28 on resting T cells by its ligand B7 results in the induction of both Th1- and Th2-type cytokines.
1994 • 27 citations
Interleukin-1 and B7/CD28 Interaction Regulate Interleukin-6 Production by Human T Cells
1994 • 26 citations
Expression and Functional Analysis of Murine B7 Delineated by a Novel Monoclonal Antibody
1994 • 25 citations
Transforming growth factor β1 regulation of macrophage activation depends on the triggering stimulus
1993 • 23 citations
Inhibitory cytokine circuits involving transforming growth factor-beta, interferon-gamma, and interleukin-2 in human monocyte activation
1994 • 23 citations
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