Cleavage of the Serum Response Factor during Death Receptor-induced Apoptosis Results in an Inhibition of the c-FOS Promoter Transcriptional Activity

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

1997 • 5,665 citations

The Bcl-2 Protein Family: Arbiters of Cell Survival

1998 • 5,359 citations

Two CD95 (APO-1/Fas) signaling pathways

1998 • 3,045 citations

Bcl-2 and the regulation of programmed cell death

1994 • 2,346 citations

Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms

1999 • 1,897 citations

The proto-oncogene Bcl-2 and its role in regulating apoptosis

1997 • 1,768 citations

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1997 • 1,305 citations

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL

1997 • 1,119 citations

PRIMARY RESPONSE GENES INDUCED BY GROWTH FACTORS AND TUMOR PROMOTERS

1991 • 1,078 citations

Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

1996 • 980 citations

Integration of MAP Kinase Signal Transduction Pathways at the Serum Response Element

1995 • 935 citations

Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

1995 • 835 citations

The MADS-Box Family of Transcription Factors

1995 • 780 citations

Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus

1995 • 758 citations

Involvement of an ICE-like protease in Fas-mediated apoptosis

1995 • 757 citations

Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element

1992 • 688 citations

Ternary complex factors: growth factor regulated transcriptional activators

1994 • 686 citations

ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation.

1995 • 667 citations

The MADS-Box Family of Transcription Factors

1995 • 645 citations

Activation of ternary complex factor Elk-1 by MAP kinases.

1993 • 561 citations

The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoter

1989 • 495 citations

Withdrawal of Survival Factors Results in Activation of the JNK Pathway in Neuronal Cells Leading to Fas Ligand Induction and Cell Death

1999 • 472 citations

Role of p38 and JNK Mitogen-Activated Protein Kinases in the Activation of Ternary Complex Factors

1997 • 467 citations

The serum response element

1992 • 458 citations

Ets-related protein Elk-1 is homologous to the c-fos regulatory factor p62TCF

1991 • 447 citations

Caspase-dependent Cleavage of Signaling Proteins during Apoptosis

1998 • 420 citations

Journey to the surface of the cell: Fos regulation and the SRE.

1995 • 376 citations

Serum response factor is essential for mesoderm formation during mouse embryogenesis

1998 • 364 citations

Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET).

1995 • 255 citations

A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity.

1993 • 253 citations

p90RSK Blocks Bad-mediated Cell Death via a Protein Kinase C-dependent Pathway

1999 • 234 citations

Differential activation of c-fos promoter elements by serum, lysophosphatidic acid, G proteins and polypeptide growth factors.

1995 • 226 citations

Convergence of MAP kinase pathways on the ternary complex factor Sap-1a

1997 • 226 citations

A caspase inhibitor fully protects rats against lethal normothermic liver ischemia by inhibition of liver apoptosis

1999 • 224 citations

Net, a new ets transcription factor that is activated by Ras.

1994 • 216 citations

Spatial flexibility in ternary complexes between SRF and its accessory proteins.

1992 • 175 citations

Pivotal role of a DEVD-sensitive step in etoposide-induced and Fas-mediated apoptotic pathways.

1996 • 167 citations

Involvement of CPP32/Yama(-like) proteases in Fas-mediated apoptosis.

1996 • 165 citations

The transcription factors Elk-1 and serum response factor interact by direct protein-protein contacts mediated by a short region of Elk-1.

1994 • 145 citations

Regulation of MCL1 through a Serum Response Factor/Elk-1-mediated Mechanism Links Expression of a Viability-promoting Member of the BCL2 Family to the Induction of Hematopoietic Cell Differentiation

1999 • 122 citations

Suppression of Fas/APO-1-Mediated Apoptosis by Mitogen-Activated Kinase Signaling

1998 • 106 citations

Cleavage and relocation of the tyrosine kinase P59FYN during Fas-mediated apoptosis in T lymphocytes

1999 • 30 citations