The effect of inhibiting DNA replication in the one-cell mouse embryo

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography

1975 • 4,693 citations

Gene Activity in Early Development

1968 • 1,725 citations

A major developmental transition in early xenopus embryos: II. control of the onset of transcription

1982 • 1,065 citations

Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase-α

1978 • 904 citations

Culture of mouse ova.

1971 • 810 citations

Gene Activity in Early Development

1976 • 655 citations

The transition from maternal to embryonic control in the 2-cell mouse embryo.

1982 • 626 citations

Activation of mammalian oocytes by intracellular injection of calcium

1978 • 582 citations

Heat shock proteins, first major products of zygotic gene activity in mouse embryo

1983 • 401 citations

Interaction of oncodazole (R 17934), a new anti-tumoral drug, with rat brain tubulin

1976 • 366 citations

A cytoplasmic clock with the same period as the division cycle in Xenopus eggs.

1980 • 358 citations

The Mechanism of Action of Inhibitors of DNA Synthesis

1977 • 330 citations

The relationship between cleavage, DNA replication, and gene expression in the mouse 2-cell embryo

1984 • 303 citations

Synchronization of HeLa cell cultures by inhibition of DNA polymerase a with aphidicolin

1980 • 291 citations

Segregation During Ascidian Embryogenesis of Egg Cytoplasmic Information for Tissue-Specific Enzyme Development

1973 • 278 citations

Sequence and regulation of morphological and molecular events during the first cell cycle of mouse embryogenesis

1985 • 249 citations

Two-dimensional gel patterns of protein synthesis before and after fertilization of sea urchin eggs

1976 • 159 citations

Factors affecting the time of formation of the mouse blastocoele

1977 • 147 citations

Evidence for expression of the paternal genome in the two-cell mouse embryo

1981 • 139 citations

The Cell Cycle and the Control of Cellular Reproduction

1976 • 132 citations

The timing of compaction: control of a major developmental transition in mouse early embryogenesis

1986 • 130 citations

A set of proteins showing cell cycle dependent modification in the early mouse embryo

1986 • 127 citations

Molecular Biology of the Sea Urchin Embryo

1982 • 125 citations

Changes in the quantity of histone and actin messenger RNA during the development of preimplantation mouse embryos

1983 • 109 citations

PERIODIC CHANGE IN THE TENSION AT THE SURFACE OF ACTIVATED NON‐NUCLEATE FRAGMENTS OF SEA‐URCHIN EGGS

1978 • 96 citations

Molecular and morphological differentiation of the mouse blastocyst after manipulations of compaction with cytochalasin D

1981 • 85 citations

Utilization of stored mRNA in Xenopus embryos and its replacement by newly synthesized transcripts: Histone H1 synthesis using interspecies hybrids

1979 • 85 citations

Poly(A) and synthesis of polyadenylated RNA in the preimplantation mouse embryo

1978 • 84 citations

Achromosomal cleavage of fertilized starfish eggs in the presence of aphidicolin

1981 • 83 citations

Differentiation of 2-cell and 8-cell mouse embryos arrested by cytoskeletal inhibitors

1980 • 81 citations

Timing Mechanisms in Early Embryonic Development

1982 • 74 citations

On the ‘clock’ mechanism determining the time of tissue-specific enzyme development during ascidian embryogenesis

1979 • 74 citations

A definite number of aphidicolin-sensitive cell-cyclic events are required for acetylcholinesterase development in the presumptive muscle cells of the ascidian embryos

1981 • 73 citations

On the ‘clock’ mechanism determining the time of tissue-specific enzyme development during ascidian embryogenesis II. Evidence for association of the clock with the cycle of DNA replication

1981 • 73 citations

Major loss of junctional coupling during mitosis in early mouse embryos.

1986 • 70 citations

Programmed development in the mouse embryo

1984 • 52 citations

Autonomous cortical activity in mouse eggs controlled by a cytoplasmic clock

1984 • 49 citations

DNA replication and compaction in the cleaving embryo of the mouse

1985 • 48 citations

Effect of delaying DNA replication on blastocyst formation in the mouse

1984 • 48 citations

Inhibition by aphidicolin of cell cycle progression and DNA replication in sea urchin embryos

1979 • 46 citations

Effects of α‐amanitin on RNA synthesis by mouse embryos in culture

1978 • 44 citations

Maturation promoting factor and cell cycle regulation

1985 • 42 citations

Uridine and guanosine incorporation by the mouse one-cell embryo

1978 • 32 citations

Inhibition of DNA replication in preimplantation mouse embryos by aphidicolin

1985 • 30 citations

Protein synthesis in mouse embryos with experimentally produced asynchrony between chromosome replication and cell division

1983 • 26 citations

Induction of cleft lip in cultured rat embryos by localized administration of tunicamycin

1981 • 25 citations

Studies on Differentiation without Cleavage in Chaetopterus: Effects of Inhibition of DNA Synthesis with Aphidicolin

1981 • 12 citations

Periodicity of Cytoplasmic Cycle in Nonnucleate Fragments of Sea Urchin and Starfish Eggs*

1985 • 9 citations

Dihydrofolate Reductase in Starfish Oocytes and Embryos: Developmental Consequences of Its Inhibition by Methotrexate¹

1985 • 6 citations