Intact LIM 3 and LIM 4 Domains of Paxillin Are Required for the Association to a Novel Polyproline Region (Pro 2) of Protein-Tyrosine Phosphatase-PEST

Cell Migration: A Physically Integrated Molecular Process

1996 • 3,909 citations

Integrins and Signal Transduction Pathways: the Road Taken

1995 • 3,002 citations

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1995 • 1,810 citations

Development of “substrate-trapping” mutants to identify physiological substrates of protein tyrosine phosphatases

1997 • 774 citations

Protein tyrosine phosphatases in signal transduction

1997 • 766 citations

LIM domains: multiple roles as adapters and functional modifiers in protein interactions

1998 • 592 citations

pp125^FAK-Dependent Tyrosine Phosphorylation of Paxillin Creates a High-Affinity Binding Site for Crk

1995 • 534 citations

From Form to Function: Signaling by Protein Tyrosine Phosphatases

1996 • 526 citations

Signaling through focal adhesion kinase

1997 • 468 citations

Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding.

1996 • 347 citations

Characterization of Tyrosine Phosphorylation of Paxillin in Vitro by Focal Adhesion Kinase

1995 • 334 citations

The LIM domain: a new structural motif found in zinc-finger-like proteins

1994 • 327 citations

Primary sequence of paxillin contains putative SH2 and SH3 domain binding motifs and multiple LIM domains: identification of a vinculin and pp125Fak- binding region

1994 • 311 citations

Protein Tyrosine Phosphatase-PEST Regulates Focal Adhesion Disassembly, Migration, and Cytokinesis in Fibroblasts

1999 • 284 citations

Direct Binding of the Proline-rich Region of Protein Tyrosine Phosphatase 1B to the Src Homology 3 Domain of p130Cas

1996 • 272 citations

Identification of p130^cas as a Substrate for the Cytosolic Protein Tyrosine Phosphatase PTP-PEST

1996 • 263 citations

Direct association of pp125FAK with paxillin, the focal adhesion-targeting mechanism of pp125FAK.

1995 • 261 citations

Epidermal Growth Factor Receptor and the Adaptor Protein p52^Shc Are Specific Substrates of T-Cell Protein Tyrosine Phosphatase

1998 • 226 citations

Identification of Major Binding Proteins and Substrates for the SH2-Containing Protein Tyrosine Phosphatase SHP-1 in Macrophages

1998 • 201 citations

Direct Association of Protein-tyrosine Phosphatase PTP-PEST with Paxillin

1998 • 176 citations

Characterization of the WW Domain of Human Yes-associated Protein and Its Polyproline-containing Ligands

1997 • 175 citations

PSTPIP: A Tyrosine Phosphorylated Cleavage Furrow–associated Protein that Is a Substrate for a PEST Tyrosine Phosphatase

1997 • 169 citations

Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition

1997 • 156 citations

Tyrosine Phosphorylation of Crk-associated Substrates by Focal Adhesion Kinase

1997 • 155 citations

Requirements for Localization of p130^cas to Focal Adhesions

1997 • 149 citations

Inhibitory Tyrosine Protein Kinase p50 Is Associated with Protein-tyrosine Phosphatase PTP-PEST in Hemopoietic and Non-hemopoietic Cells

1997 • 139 citations

Regulation of Fibroblast Motility by the Protein Tyrosine Phosphatase PTP-PEST

1999 • 136 citations

Serine and Threonine Phosphorylation of the Paxillin LIM Domains Regulates Paxillin Focal Adhesion Localization and Cell Adhesion to Fibronectin

1998 • 136 citations

Paxillin LD motifs may define a new family of protein recognition domains

1998 • 112 citations

Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin

1997 • 112 citations

Specificity of LIM Domain Interactions with Receptor Tyrosine Kinases

1996 • 108 citations

Combination of Gene Targeting and Substrate Trapping to Identify Substrates of Protein Tyrosine Phosphatases Using PTP-PEST as a Model

1998 • 105 citations

Induction of Senescence-Like Phenotypes by Forced Expression of hic-5, Which Encodes a Novel LIM Motif Protein, in Immortalized Human Fibroblasts

1997 • 97 citations

Leupaxin Is a Novel LIM Domain Protein That Forms a Complex with PYK2

1998 • 92 citations

Hic-5, a Paxillin Homologue, Binds to the Protein-tyrosine Phosphatase PEST (PTP-PEST) through Its LIM 3 Domain

1999 • 89 citations

Phosphotyrosine-independent Binding of SHC to the NPLH Sequence of Murine Protein-tyrosine Phosphatase-PEST

1996 • 78 citations

Murine protein tyrosine phosphatase-PEST, a stable cytosolic protein tyrosine phosphatase

1995 • 70 citations

Activators of protein kinase C stimulate association of Shc and the PEST tyrosine phosphatase.

1994 • 62 citations

Coupling of the murine protein tyrosine phosphatase PEST to the epidermal growth factor (EGF) receptor through a Src homology 3 (SH3) domain-mediated association with Grb2

1997 • 50 citations