A major role for VCAM-1, but not ICAM-1, in early atherosclerosis

Atherosclerosis — An Inflammatory Disease

1999 • 21,494 citations

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Decreased lesion formation in CCR2−/− mice reveals a role for chemokines in the initiation of atherosclerosis

1998 • 1,943 citations

Endothelial Expression of a Mononuclear Leukocyte Adhesion Molecule During Atherogenesis

1991 • 1,703 citations

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.

1993 • 1,578 citations

Absence of Monocyte Chemoattractant Protein-1 Reduces Atherosclerosis in Low Density Lipoprotein Receptor–Deficient Mice

1998 • 1,569 citations

Simplified mammalian DNA isolation procedure

1991 • 1,508 citations

Upregulation of VCAM-1 and ICAM-1 at Atherosclerosis-Prone Sites on the Endothelium in the ApoE-Deficient Mouse

1998 • 890 citations

Cell adhesion events mediated by α4 integrins are essential in placental and cardiac development

1995 • 792 citations

Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis.

1991 • 628 citations

Patterns of Vascular Cell Adhesion Molecule-1 and Intercellular Adhesion Molecule-1 Expression in Rabbit and Mouse Atherosclerotic Lesions and at Sites Predisposed to Lesion Formation

1999 • 618 citations

Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1.

1993 • 563 citations

Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice

1995 • 554 citations

A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice.

1998 • 525 citations

Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice.

1994 • 492 citations

P-Selectin or Intercellular Adhesion Molecule (Icam)-1 Deficiency Substantially Protects against Atherosclerosis in Apolipoprotein E–Deficient Mice

2000 • 472 citations

The combined role of P- and E-selectins in atherosclerosis.

1998 • 444 citations

Requirement for CD154 in the progression of atherosclerosis

1999 • 437 citations

Vascular cell adhesion molecule-1 expressed by bone marrow stromal cells mediates the binding of hematopoietic progenitor cells

1992 • 417 citations

Roles for the integrin VLA-4 and its counter receptor VCAM-1 in myogenesis

1992 • 404 citations

A VCAM-like adhesion molecule on murine bone marrow stromal cells mediates binding of lymphocyte precursors in culture.

1991 • 399 citations

Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation.

1995 • 393 citations

Vascular cell adhesion molecule-1 expressed by bone marrow stromal cells mediates the binding of hematopoietic progenitor cells

1992 • 300 citations

Adhesion of Human B Cells to Germinal Centers in Vitro Involves VLA-4 and INCAM-110

1990 • 295 citations

Direct Demonstration of P-Selectin– and VCAM-1–Dependent Mononuclear Cell Rolling in Early Atherosclerotic Lesions of Apolipoprotein E–Deficient Mice

1999 • 266 citations

Prominent Role of P-Selectin in the Development of Advanced Atherosclerosis in ApoE-Deficient Mice

2000 • 262 citations

Absence of P-selectin delays fatty streak formation in mice.

1997 • 241 citations

Role of Vascular Cell Adhesion Molecule-1 and Fibronectin Connecting Segment-1 in Monocyte Rolling and Adhesion on Early Atherosclerotic Lesions

2000 • 231 citations

Gene structure, chromosomal location, and basis for alternative mRNA splicing of the human VCAM1 gene.

1991 • 186 citations

Hyperlipidemia and Atherosclerotic Lesion Development in LDL Receptor–Deficient Mice Fed Defined Semipurified Diets With and Without Cholate

1999 • 174 citations

Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4.

1994 • 165 citations

ICAM-1 Deficiency Reduces Atherosclerotic Lesions in Double-Knockout Mice (ApoE ^{− /−} /ICAM-1 ^{− /−} ) Fed a Fat or a Chow Diet

2000 • 153 citations

Simplified northern blot hybridization using 5% sodium dodecyl sulfate.

1990 • 149 citations

Novel isoforms of murine intercellular adhesion molecule-1 generated by alternative RNA splicing.

1995 • 146 citations

Arrangement of domains, and amino acid residues required for binding of vascular cell adhesion molecule-1 to its counter-receptor VLA-4 (alpha 4 beta 1)

1994 • 142 citations

Morphology and cell kinetics of fatty streak lesion formation in the hypercholesterolemic rabbit.

1986 • 76 citations

Activation‐Dependent Isolation and Culture of Murine Pulmonary Microvascular Endothelium

1995 • 67 citations

Circulating forms of intercellular adhesion molecule (ICAM)-1 in mice lacking membranous ICAM-1

2000 • 65 citations

Differential up-regulation of circulating soluble and endothelial cell intercellular adhesion molecule-1 in mice.

1997 • 46 citations

Vascular cell adhesion molecule‐1 expression by hematopoiesis‐supporting stromal cells is not essential for lymphoid or myeloid differentiation in vivo or in vitro

1996 • 44 citations

Mouse Chromosome 9

1992 • 39 citations

Structure of the Murine VCAM1 Gene

1993 • 35 citations

Mouse models of atherosclerosis.

1998 • 34 citations

Improved nonradioactive cell surface labeling technique for immunoprecipitation.

1995 • 18 citations