Measurement of kynurenic acid in mammalian brain extracts and cerebrospinal fluid by high-performance liquid chromatography with fluorometric and coulometric electrode array detection

Glycine potentiates the NMDA response in cultured mouse brain neurons

1987 • 3,116 citations

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

1984 • 1,689 citations

Fluorometric assay of proteins in the nanogram range

1973 • 1,640 citations

Requirement for Glycine in Activation of NMDA-Receptors Expressed in Xenopus Oocytes

1988 • 1,415 citations

Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid

1986 • 1,283 citations

Lesion of striatal neurons with kainic acid provides a model for Huntington's chorea

1976 • 1,247 citations

Quinoxalinediones: Potent Competitive Non-NMDA Glutamate Receptor Antagonists

1988 • 1,202 citations

An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid

1982 • 834 citations

Duplication of biochemical changes of Huntington's chorea by intrastriatal injections of glutamic and kainic acids

1976 • 832 citations

A Glycine Site Associated with N‐Methyl‐<scp>d</scp>‐Aspartic Acid Receptors: Characterization and Identification of a New Class of Antagonists

1989 • 723 citations

Hypoglycemia-Induced Neuronal Damage Prevented by an N -Methyl-D-Aspartate Antagonist

1985 • 673 citations

HUNTINGTON'S CHOREA

1974 • 527 citations

II. Excitotoxic models for neurodegenerative disorders

1984 • 469 citations

Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid

1984 • 416 citations

Regulation of NMDA receptor desensitization in mouse hippocampal neurons by glycine

1989 • 408 citations

Quinolinic acid and other kynurenines in the central nervous system

1985 • 311 citations

Kynurenic acid inhibits synaptic and acidic amino acid-induced responses in the rat hippocampus and spinal cord

1983 • 307 citations

Kynurenic acid antagonises responses to NMDA via an action at the strychnine-insensitive glycine receptor

1988 • 307 citations

l-Kynurenine Its synthesis and possible regulatory function in brain

1980 • 299 citations

Presence of Kynurenic Acid in the Mammalian Brain

1988 • 273 citations

Glycine enhances NMDA-receptor mediated synaptic potentials in neocortical slices

1989 • 234 citations

NMDA receptors and ligands in the vertebrate CNS

1988 • 226 citations

Rat Brain Slices Produce and Liberate Kynurenic Acid upon Exposure to <scp>l</scp>‐Kynurenine

1989 • 221 citations

Identification and quantification of kynurenic acid in human brain tissue

1988 • 217 citations

Excitatory Amino Acids and Epilepsy

1986 • 204 citations

n-Electrode three-dimensional liquid chromatography with electrochemical detection for determination of neurotransmitters.

1984 • 203 citations

6,7-Dinitro-quinoxaline-2,3-dion and 6-nitro,7-cyano-quinoxaline-2,3-dion antagonise responses to NMDA in the rat spinal cord via an action at the strychnine-insensitive glycine receptor

1988 • 197 citations

Differential sparing of somatostatin‐neuropeptide y and cholinergic neurons following striatal excitotoxin lesions

1989 • 197 citations

Ion-pair high-performance liquid chromatography

1978 • 190 citations

SYNTHESIS AND METABOLISM OF <scp>l</scp>‐KYNURENINE IN RAT BRAIN

1978 • 173 citations

Practical Aspects off Reverse Phase Ion Pair Chromatography

1977 • 173 citations

Kynurenate and FG9041 have both competitive and non-competitive antagonist actions at excitatory amino acid receptors

1988 • 163 citations

Seizure-like activity and cellular damage in rat hippocampal neurons in cell culture

1989 • 156 citations

Modulation of excitatory synaptic transmission by glycine and zinc in cultures of mouse hippocampal neurons

1988 • 146 citations

Interaction of 6-cyano-7-nitroquinoxaline-2,3-dione with the N-methyl-D-aspartate receptor-associated glycine binding site.

1989 • 143 citations

Fluorimetric micro-determination of kynurenic acid, an endogenous blocker of neurotoxicity, by high-performance liquid chromatography

1988 • 142 citations

HA-966 antagonizes N-methyl-D-aspartate receptors through a selective interaction with the glycine modulatory site

1989 • 128 citations

Post‐mortem stability of dopamine. glutamate decarboxylase and choline acetyltransferase in the mouse brain under conditions simulating the handling of human autopsy material

1978 • 122 citations

Kynurenic acid is present in the rat brain and its content increases during development and aging processes

1988 • 113 citations

High-affinity uptake of L-kynurenine by a Na+-independent transporter of neutral amino acids in astrocytes

1989 • 107 citations

EC array sensor concepts and data

1987 • 93 citations

Actions of kynurenic acid and quinolinic acid in the rat hippocampus in vivo

1985 • 90 citations

Estrogen-Enzyme Interactions: Inhibition and Protection of Kynurenine Transaminase by the Sulfate Esters of Diethylstilbestrol, Estradiol, and Estrone

1960 • 84 citations

THE KYNURENINE TRANSAMINASE OF RAT KIDNEY

1954 • 80 citations

TRYPTOPHAN METABOLISM

1949 • 77 citations

Cerebral tryptophan‐2,3‐dioxygenase (pyrrolase) and its induction in rat brain

1974 • 69 citations

KYNURENINE TRANSAMINASE OF RAT KIDNEY: A STUDY OF COENZYME DISSOCIATION

1957 • 62 citations

Glycine maintains excitement

1989 • 61 citations

Increase in Kynurenic Acid in Huntington's Disease Motor Cortex

1989 • 57 citations

Kynurenate and 2-amino-5-phosphonovalerate interact with multiple binding sites of the glutamate receptor domain

1989 • 52 citations

Die Entstehung der Kynurensäure.

1905 • 49 citations

Identification and measurement of kynurenic acid in the rat brain and other organs

1988 • 44 citations

Kynurenine Transaminase: A Study of Inhibitors and Their Relationship to the Active Site

1959 • 41 citations

Crystallization and characterization of human liver kynurenine–glyoxylate aminotransferase. Identity with alanine–glyoxylate aminotransferase and serine–pyruvate aminotransferase

1980 • 39 citations

Kynurenine pyruvate transaminase in rat brain

1974 • 32 citations

Glycine reverses 7-Cl kynurenate blockade of glutamate neurotoxicity in cell culture

1989 • 29 citations

Quisqualate receptor antagonists

1988 • 26 citations

THE CONSTITUTION OF KYNURENIC ACID

1914 • 22 citations

Kynurenine pyruvate transaminase and its inhibitor in rat intestine

1973 • 19 citations