Phase II trial of 5-fluorouracil and folinic acid in the treatment of advanced breast cancer

Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma.

1989 • 911 citations

The modulation of fluorouracil with leucovorin in metastatic colorectal carcinoma: a prospective randomized phase III trial. Gastrointestinal Tumor Study Group.

1989 • 561 citations

A randomized trial of fluorouracil and folinic acid in patients with metastatic colorectal carcinoma.

1988 • 513 citations

A randomized trial of two dose levels of cyclophosphamide, methotrexate, and fluorouracil chemotherapy for patients with metastatic breast cancer.

1988 • 354 citations

The Modulation of Fluorouracil With Leucovorin in Metastatic Colorectal Carcinoma

1990 • 287 citations

Effect of excess folates and deoxyinosine on the activity and site of action of 5-fluorouracil.

1981 • 287 citations

Inhibition of fluorouracil-induced stomatitis by oral cryotherapy.

1991 • 255 citations

Fluorouracil and high-dose leucovorin in previously treated patients with metastatic breast cancer.

1989 • 246 citations

A randomized comparison of single-agent doxorubicin and epirubicin as first-line cytotoxic therapy in advanced breast cancer.

1991 • 117 citations

A randomized multicenter trial comparing mitoxantrone, cyclophosphamide, and fluorouracil with doxorubicin, cyclophosphamide, and fluorouracil in the therapy of metastatic breast carcinoma.

1988 • 110 citations

Relationship of cellular folate cofactor pools to the activity of 5-fluorouracil.

1983 • 96 citations

A controlled evaluation of an allopurinol mouthwash as prophylaxis against 5-fluorouracil-induced stomatitis

1990 • 95 citations

A prospective randomized trial comparing epirubicin monochemotherapy to two fluorouracil, cyclophosphamide, and epirubicin regimens differing in epirubicin dose in advanced breast cancer patients. The French Epirubicin Study Group.

1991 • 82 citations

Breast Cancer: Diagnosis and Management

1985 • 82 citations

The effect on survival of initial chemotherapy in advanced breast cancer: polychemotherapy versus single drug.

1987 • 64 citations

Refractory metastatic breast cancer: salvage therapy with fluorouracil and high-dose continuous infusion leucovorin calcium.

1989 • 62 citations

5-Fluorouracil by Protracted Venous Infusion: A Review of Recent Clinical Studies

1991 • 51 citations

5-Fluorouracil and High-Dose Folinic Acid as Salvage Treatment of Advanced Breast Cancer: An Update

1987 • 37 citations

5-fluorouracil with leucovorin in breast cancer

1989 • 26 citations

Cyclophosphamide, epirubicin, high-dose folinic acid and 5-fluorouracil (super-FEC) as first-line chemotherapy for advanced breast cancer: Preliminary results

1989 • 12 citations

Sequential Administration of Cyclophosphamide, Methotrexate, 5-Fluorouracil, and Folinic Acid as Salvage Treatment in Metastatic Breast Cancer

1987 • 8 citations

Allopurinol mouthwash for prevention of fluorouracil-induced stomatitis.

1989 • 6 citations