Molecular motors in axonal transport

Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

1985 • 1,930 citations

X-Ray Structure of the GCN4 Leucine Zipper, a Two-Stranded, Parallel Coiled Coil

1991 • 1,433 citations

Intracellular transport in neurons.

1980 • 1,011 citations

The slow component of axonal transport. Identification of major structural polypeptides of the axon and their generality among mammalian neurons.

1975 • 937 citations

Movement of microtubules by single kinesin molecules

1989 • 878 citations

Basic Neurochemistry: Molecular, Cellular, and Medical Aspects

1989 • 837 citations

Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic

1991 • 757 citations

Cross-linker system between neurofilaments, microtubules and membranous organelles in frog axons revealed by the quick-freeze, deep-etching method

1982 • 672 citations

A novel brain ATPase with properties expected for the fast axonal transport motor

1985 • 604 citations

Retrograde transport by the microtubule-associated protein MAP 1C

1987 • 547 citations

Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis

1991 • 543 citations

Fodrin: axonally transported polypeptides associated with the internal periphery of many cells.

1981 • 480 citations

Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro

1985 • 463 citations

Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration

1989 • 460 citations

Gliding movement of and bidirectional transport along single native microtubules from squid axoplasm: evidence for an active role of microtubules in cytoplasmic transport.

1985 • 440 citations

Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubules

1989 • 436 citations

Video‐enhanced contrast, differential interference contrast (AVEC‐DIC) microscopy: A new method capable of analyzing microtubule‐related motility in the reticulopodial network of allogromia laticollaris

1981 • 419 citations

A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses

1989 • 392 citations

Single microtubules from squid axoplasm support bidirectional movement of organelles

1985 • 363 citations

Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins

1990 • 352 citations

Microtubule behavior in the growth cones of living neurons during axon elongation.

1991 • 343 citations

Dynein is the motor for retrograde axonal transport of organelles.

1989 • 334 citations

Fast Axonal Transport in Extruded Axoplasm from Squid Giant Axon

1982 • 333 citations

Slow components of axonal transport: two cytoskeletal networks.

1980 • 318 citations

Cytoplasmic dynein is a minus end-directed motor for membranous organelles

1989 • 313 citations

Native structure and physical properties of bovine brain kinesin and identification of the ATP-binding subunit polypeptide

1988 • 284 citations

Assembly of microtubules at the tip of growing axons

1986 • 277 citations

Thrombospondin modulates focal adhesions in endothelial cells.

1989 • 271 citations

Mechanisms of Fast and Slow Axonal Transport

1991 • 269 citations

Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells.

1989 • 261 citations

Multiple fates of newly synthesized neurofilament proteins: evidence for a stationary neurofilament network distributed nonuniformly along axons of retinal ganglion cell neurons.

1986 • 248 citations

Identification of globular mechanochemical heads of kinesin

1989 • 231 citations

Multiple nucleotide-binding sites in the sequence of dynein β heavy chain

1991 • 229 citations

Evidence that the Head of Kinesin Is Sufficient for Force Generation and Motility in Vitro

1990 • 225 citations

The Polypeptide Composition of Intra-axonally Transported Proteins: Evidence for Four Transport Velocities

1974 • 223 citations

Microtubule behavior during guidance of pioneer neuron growth cones in situ.

1991 • 218 citations

Stable polymers of the axonal cytoskeleton: the axoplasmic ghost.

1982 • 216 citations

Bovine brain kinesin is a microtubule-activated ATPase.

1986 • 215 citations

The neural network underlying locomotion in lamprey-synaptic and cellular mechanisms

1991 • 203 citations

Video microscopy of fast axonal transport in extruded axoplasm: A new model for study of molecular mechanisms

1985 • 193 citations

Cross-bridges mediate anterograde and retrograde vesicle transport along microtubules in squid axoplasm.

1985 • 187 citations

Attachment of transported vesicles to microtubules in axoplasm is facilitated by AMP-PNP

1985 • 184 citations

Axonal Transport: Each Major Rate Component Reflects the Movement of Distinct Macromolecular Complexes

1981 • 179 citations

The quaternary structure of bovine brain kinesin.

1988 • 178 citations

Four ATP-binding sites in the midregion of the β heavy chain of dynein

1991 • 175 citations

Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued

1991 • 174 citations

Targeting proteins into mitochondria

1986 • 171 citations

Microtubule polymer assembly and transport during axonal elongation.

1991 • 164 citations

Nerve-specific enolase and creatine phosphokinase in axonal transport: soluble proteins and the axoplasmic matrix

1981 • 156 citations

Characterization of the microtubule movement produced by sea urchin egg kinesin.

1987 • 153 citations

Squid as Experimental Animals

1990 • 147 citations

Characterization of the microtubule-activated ATPase of brain cytoplasmic dynein (MAP 1C).

1988 • 142 citations

Molecular motors in the nervous system

1991 • 141 citations

Axonal transport of actin: Slow component b is the principal source of actin for the axon

1979 • 137 citations

Association of kinesin with characterized membrane‐bounded organelles

1992 • 135 citations

Mechanisms of Intracellular Organelle Transport

1984 • 128 citations

Drosophila kinesin: characterization of microtubule motility and ATPase.

1988 • 120 citations

Molecular genetics of kinesin light chains: generation of isoforms by alternative splicing.

1991 • 119 citations

Subcellular localization and sequence of sea urchin kinesin heavy chain: evidence for its association with membranes in the mitotic apparatus and interphase cytoplasm [published erratum appears in J Cell Biol 1991 Aug;114(4):following 863]

1991 • 112 citations

Quantitative analysis of sea urchin egg kinesin-driven microtubule motility

1989 • 111 citations

Detection of single microtubules in living cells: particle transport can occur in both directions along the same microtubule.

1984 • 110 citations

Correlation between the ATPase and microtubule translocating activities of sea urchin egg kinesin

1987 • 110 citations

RAPID INTRACELLULAR TRANSPORT OF FUCOSE‐CONTAINING GLYCOPROTEINS IN RETINAL GANGLION CELLS

1971 • 105 citations

Gelsolin inhibition of fast axonal transport indicates a requirement for actin microfilaments

1984 • 104 citations

The role of dynein in retrograde axonal transport

1989 • 101 citations

Isolation of a 45-kDa Fragment from the Kinesin Heavy Chain with Enhanced ATPase and Microtubule-binding Activities

1989 • 96 citations

Isolation and characterization of the gene encoding the heavy chain of Drosophila kinesin.

1988 • 92 citations

The primary structure and analysis of the squid kinesin heavy chain.

1990 • 92 citations

Axonal transport of a subclass of tau proteins: evidence for the regional differentiation of microtubules in neurons.

1984 • 91 citations

Copurification of kinesin polypeptides with microtubule‐stimulated Mg‐ATPase activity and kinetic analysis of enzymatic properties

1989 • 90 citations

Axonal transport of actin in rabbit retinal ganglion cells.

1979 • 89 citations

Motor proteins for cytoplasmic microtubules

1992 • 87 citations

Axonal transport of calmodulin: a physiologic approach to identification of long-term associations between proteins.

1981 • 82 citations

Clathrin is axonally transported as part of slow component b: the microfilament complex.

1981 • 81 citations

A dynamin-like protein encoded by the yeast sporulation gene SP015

1991 • 80 citations

TRANSPORT OF MICROTUBULAR PROTEIN IN AXONS OF RETINAL GANGLION CELLS

1971 • 76 citations

Chapter 18 Axonal Transport: A Cell-Biological Method for Studying Proteins That Associate with the Cytoskeleton

1982 • 70 citations

Targeting proteins into mitochondria.

1986 • 70 citations

Identification of a MAP 2-like ATP-binding protein associated with axoplasmic vesicles that translocate on isolated microtubules.

1986 • 65 citations

Cohesive axonal transport of the slow component b complex of polypeptides

1982 • 62 citations

Membrane delivery by fast axonal transport

1982 • 61 citations

The identification of two intra-axonally transported polypeptides resembling myosin in some respects in the rabbit visual system.

1977 • 56 citations

Slow Transport of Tubulin in the Neurites of Differentiated PC12 Cells

1987 • 53 citations

Chick brain actin and myosin. Isolation and characterization.

1979 • 49 citations

Witold Drabikowski (1925–1983)

1984 • 44 citations

Purification and characterization of kinesin from bovine adrenal medulla.

1988 • 40 citations

Slow axonal transport models come full circle: Evidence that microtubule sliding mediates axon elongation and tubulin transport

1991 • 40 citations

Investigation of the Axonal Transport of Three Acidic, Soluble Proteins (14‐3‐2, 14‐3‐3, and S‐100) in the Rabbit Visual System

1980 • 39 citations

Evidence that the 116 kDa component of kinesin binds and hydrolyses ATP

1987 • 32 citations

General Neurochemical Techniques

1986 • 19 citations

Axonal Transport Methods and Applications

2003 • 17 citations

Fast axonal transport in auditory neurons of the guinea pig: a rapidly turned-over glycoprotein.

1980 • 15 citations

Microtubule gelation‐contraction in vitro and its relationship to component a of slow axonal transport

1988 • 9 citations

The recovery of organelle transport and microtubule integrity in myelinated axons that are frozen and thawed

1985 • 8 citations

Cytotypic Specialization of the Neuronal Cytoskeleton and the Cytomatrix: Implications for Neuronal Growth and Regeneration

1988 • 7 citations

Cytoplasm and cell motility Editorial overview

1992 • 2 citations