Cytotypic Specialization of the Neuronal Cytoskeleton and the Cytomatrix: Implications for Neuronal Growth and Regeneration

Dynamic instability of microtubule growth

1984 • 3,187 citations

The period of susceptibility to the physiological effects of unilateral eye closure in kittens

1970 • 2,965 citations

Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ.

1983 • 1,162 citations

Intracellular transport in neurons.

1980 • 1,011 citations

The slow component of axonal transport. Identification of major structural polypeptides of the axon and their generality among mammalian neurons.

1975 • 937 citations

Microtubules containing acetylated alpha-tubulin in mammalian cells in culture.

1987 • 833 citations

ULTRASTRUCTURE AND FUNCTION OF GROWTH CONES AND AXONS OF CULTURED NERVE CELLS

1971 • 769 citations

Cross-linker system between neurofilaments, microtubules and membranous organelles in frog axons revealed by the quick-freeze, deep-etching method

1982 • 672 citations

A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs).

1982 • 553 citations

Distinct populations of microtubules: Tyrosinated and nontyrosinated alpha tubulin are distributed differently in vivo

1984 • 532 citations

Axon caliber related to neurofilaments and microtubules in sciatic nerve fibers of rats and mice

1970 • 525 citations

The periodic association of MAP2 with brain microtubules in vitro.

1979 • 510 citations

Organization of mammalian neurofilament polypeptides within the neuronal cytoskeleton.

1984 • 496 citations

Chlamydomonas .alpha.-tubulin is posttranslationally modified by acetylation on the .epsilon.-amino group of a lysine

1985 • 464 citations

Microtubules

1984 • 405 citations

Differential expression of neurofilament triplet proteins in brain development

1982 • 397 citations

Distribution of microtubule-associated protein 2 in the nervous system of the rat studied by immunofluorescence

1984 • 378 citations

High molecular weight microtubule-associated proteins are preferentially associated with dendritic microtubules in brain.

1981 • 363 citations

Differential subcellular localization of tubulin and the microtubule- associated protein MAP2 in brain tissue as revealed by immunocytochemistry with monoclonal hybridoma antibodies

1984 • 346 citations

Differences in the cellular distributions of two microtubule-associated proteins, MAP1 and MAP2, in rat brain

1984 • 326 citations

Slow components of axonal transport: two cytoskeletal networks.

1980 • 318 citations

MAP2 is localized to the dendrites of hippocampal neurons which develop in culture

1984 • 313 citations

An immunofluorescence microscopical study of the neurofilament triplet proteins, vimentin and glial fibrillary acidic protein within the adult rat brain.

1981 • 304 citations

The testis-specific β-tubulin subunit in drosophila melanogaster has multiple functions in spermatogenesis

1982 • 285 citations

Radioimmunoassay for tubulin: a quantitative comparison of the tubulin content of different established tissue culture cells and tissues

1978 • 253 citations

Organization of neuronal microtubules in the nematode Caenorhabditis elegans.

1979 • 247 citations

Widespread distribution of the major polypeptide component of MAP 1 (microtubule-associated protein 1) in the nervous system.

1984 • 238 citations

Heterogeneity of microtubule-associated protein 2 during rat brain development.

1984 • 236 citations

Biochemical and immunological analyses of cytoskeletal domains of neurons.

1986 • 230 citations

Changes in neurofilament transport coincide temporally with alterations in the caliber of axons in regenerating motor fibers.

1985 • 228 citations

Movement and extension of isolated growth cones

1977 • 213 citations

Cyclic Adenosine 3′:5′-Monophosphate-Stimulated Phosphorylation of Isolated Neurotubule Subunits

1970 • 206 citations

Regulation of tubulin and actin mRNA production in rat brain: expression of a new beta-tubulin mRNA with development.

1983 • 205 citations

Identification of two human beta-tubulin isotypes.

1983 • 203 citations

Modulations of neurofilament axonal transport during the development of rabbit retinal ganglion cells

1983 • 193 citations

Polarity of axoplasmic microtubules in the olfactory nerve of the frog.

1981 • 188 citations

Correlation of axonal regeneration and slow component B in two branches of a single axon

1983 • 178 citations

Axonal tubulin and axonal microtubules: biochemical evidence for cold stability.

1984 • 167 citations

Development of synaptic patterns in the superior colliculus of the rat

1972 • 165 citations

Studies on the expression of the microtubule-associated protein, tau, during mouse brain development, with newly isolated complementary DNA probes.

1984 • 164 citations

Changes in composition and activity of microtubule-associated proteins during brain development

1980 • 159 citations

Heterogeneity of Microtubule‐Associated Proteins and Brain Development

1982 • 156 citations

Mutation in a testis-specific β-tubulin in Drosophila: Analysis of its effects on meiosis and map location of the gene

1980 • 152 citations

Intermediate Filaments

1985 • 147 citations

Polymerization of tubulin in vivo: direct evidence for assembly onto microtubule ends and from centrosomes.

1985 • 142 citations

Slowing of neurofilament transport and the radial growth of developing nerve fibers

1985 • 139 citations

Biological Functions of Microtubules and Related Structures

1982 • 138 citations

Cytotypic differences in the protein composition of the axonally transported cytoskeleton in mammalian neurons

1987 • 130 citations

Plasticity in the developing visual system: The effects of retinal lesions made in young rats

1976 • 130 citations

Mechanisms of Intracellular Organelle Transport

1984 • 128 citations

Slowing of the axonal transport of neurofilament proteins during development

1983 • 127 citations

Differential Expression of Two Neural Cell-Specific β-Tubulin mRNAs During Rat Brain Development

1984 • 114 citations

Studies on the pathogenesis of vincristine‐induced neuropathy

1987 • 112 citations

Nerve, organ, and tissue regeneration : research perspectives

1983 • 109 citations

Subfractionation of Chlamydomonas 18 S dynein into two unique subunits containing ATPase activity.

1984 • 108 citations

Developmental changes in microtubule protein of chick brain

1973 • 107 citations

Four unique genes required for β tubulin expression in vertebrates

1983 • 105 citations

AXON‐SCHWANN CELL RELATIONSHIPS IN NEUROPATHIES OF MUTANT MICE *

1979 • 105 citations

The dynamic ordering of neuronal cytoskeletons.

1981 • 104 citations

Diversity in the axonal transport of structural proteins: major differences between optic and spinal axons in the rat

1986 • 104 citations

Polymorphism of brain tubulin

1981 • 100 citations

Axonal transport of a subclass of tau proteins: evidence for the regional differentiation of microtubules in neurons.

1984 • 91 citations

Biological structures and coupled flows

1984 • 88 citations

Molecular analysis of cytoplasmic microtubules in situ: Identification of both widespread and specific proteins

1981 • 83 citations

Solubility properties of neuronal tubulin: Evidence for labile and stable microtubules

1984 • 81 citations

Heterogeneity of vertebrate brain tubulins.

1984 • 80 citations

Translocation of the neuronal cytoskeleton and axonal locomotion

1982 • 77 citations

Chapter 15 The Cyclic Tyrosination/Detyrosination of Alpha Tubulin

1982 • 77 citations

Structure and Function in Excitable Cells

1983 • 76 citations

MAP3: characterization of a novel microtubule-associated protein.

1985 • 75 citations

Axonal Transport in Neuronal Growth and Regeneration

1984 • 74 citations

Differences in surface morphology of microtubules reconstituted from pure brain tubulin using two different microtubule-associated proteins: the high molecular weight MAP 2 proteins and tau proteins.

1979 • 70 citations

The tubulins: From DNA to RNA to protein and back again

1983 • 63 citations

Tubulin Isotypes and the Multigene Tubulin Families

1983 • 62 citations

Spatial organization of axonal microtubules.

1984 • 61 citations

Differential expression of two neural cell-specific beta-tubulin mRNAs during rat brain development.

1984 • 58 citations

Axonal tubulin and microtubules: Morphologic evidence for stable regions on axonal microtubules

1987 • 56 citations

Microtubule-associated proteins of neurons.

1983 • 56 citations

Two Populations of Axonally Transported Tubulin Differentiated by Their Interactions with Neurofilaments

1984 • 55 citations

The cytoskeleton of neurites after microtubule depolymerization

1986 • 53 citations

Increased tubulin messenger RNA in the goldfish retina during optic nerve regeneration

1979 • 52 citations

Analysis of microtubule number and length in cytoskeletons of cultured chick sensory neurons

1982 • 51 citations

ROLE OF THE AXONAL CYTOSKELETON IN THE REGENERATING NERVOUS SYSTEM

1983 • 49 citations

Labeling of Chlamydomonas 18 S dynein polypeptides by 8-azidoadenosine 5'-triphosphate, a photoaffinity analog of ATP.

1985 • 45 citations

Witold Drabikowski (1925–1983)

1984 • 44 citations

Axonal Transport of Microtubule Proteins: Cytotypic Variation of Tubulin and MAPs in Neuronsa

1986 • 41 citations

Intracellular control of axial shape in non-uniform neurites: a serial electron microscopic analysis of organelles and microtubules in AI and AII retinal amacrine neurites.

1984 • 40 citations

Post-translational modification of neuronal proteins: evidence for transglutaminase activity in R2, the giant cholinergic neuron of Aplysia.

1982 • 40 citations

Packing volume of sedimented microtubules: regulation and potential relationship to an intracellular matrix.

1985 • 39 citations

Axonal sub-populations in the central nervous system demonstrated using monoclonal antibodies against alpha-tubulin.

1983 • 38 citations

The structure and amount of tubulin in cells and tissues

1979 • 36 citations

Effect of changes in neurofilament content on caliber of small axons: the beta,beta'-iminodipropionitrile model

1987 • 30 citations

Comparison of the effects of microtubule-associated protein 2 and tau on the packing density of in vitro assembled microtubules.

1987 • 28 citations

Tubulin in the nervous system

1982 • 27 citations

Neurotubules: Different densities in peripheral motor and sensory nerve fibres

1975 • 26 citations

Differential Expression of the Three Neurofilament Polypeptides^a

1985 • 23 citations

Subunit composition specific to axonally transported tubulin

1983 • 21 citations

THE MICROTUBULE-NEUROFILAMENT NETWORK: THE BALANCE BETWEEN PLASTICITY AND STABILITY IN THE NERVOUS SYSTEM

1982 • 19 citations

Axonally Transported Proteins in Axon Development, Maintenance, and Regeneration

1983 • 15 citations

Metabolism and Axonal Transport of Polyamines in a Single Identified Neuron of Aplysia californica

1982 • 14 citations

The Neuroplasmic Lattice

1983 • 14 citations

Isolation and Characterization of Two Rat Alpha‐Tubulin Isotypesa

1986 • 12 citations

Basic Properties of Fast Axonal Transport and the Role of Fast Transport in Axonal Growth

1984 • 12 citations

α-Tubulin is not detyrosylated during axonal transport

1986 • 11 citations

<b>TWO DISTINCT COMPONENTS OF TUBULIN TRANSPORT IN SENSORY AXONS OF THE RAT RECOGNISED BY DIMETHYL SULFOXIDE </b><b>TREATMENT </b>

1983 • 10 citations

Determinants of neuronal form

1984 • 9 citations

Slow Axonal Transport in Nerve from Mice with a Genetic Myelin Deficiency (Trembler)

1988 • 1 citations